| Discovery and preclinical validation of drug indications using compendia of public gene expression data M Sirota, JT Dudley, J Kim, AP Chiang, AA Morgan, A Sweet-Cordero, ... Science translational medicine 3 (96), 96ra77-96ra77, 2011 | 888 | 2011 |
| An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis A Sweet-Cordero, S Mukherjee, A Subramanian, H You, JJ Roix, ... Nature genetics 37 (1), 48-55, 2005 | 497 | 2005 |
| Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma PK Mazur, A Herner, SS Mello, M Wirth, S Hausmann, FJ Sánchez-Rivera, ... Nature medicine 21 (10), 1163-1171, 2015 | 391 | 2015 |
| Genome-informed targeted therapy for osteosarcoma LC Sayles, MR Breese, AL Koehne, SG Leung, AG Lee, HY Liu, ... Cancer discovery 9 (1), 46-63, 2019 | 324 | 2019 |
| Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma BE Schaffer, KS Park, G Yiu, JF Conklin, C Lin, DL Burkhart, AN Karnezis, ... Cancer research 70 (10), 3877-3883, 2010 | 257 | 2010 |
| Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer TG Oliver, KL Mercer, LC Sayles, JR Burke, D Mendus, KS Lovejoy, ... Genes & development 24 (8), 837-852, 2010 | 247 | 2010 |
| Oncogenic KRAS regulates amino acid homeostasis and asparagine biosynthesis via ATF4 and alters sensitivity to L-asparaginase DM Gwinn, AG Lee, M Briones-Martin-del-Campo, CS Conn, DR Simpson, ... Cancer cell 33 (1), 91-107. e6, 2018 | 211 | 2018 |
| The genomic landscape of pediatric cancers: Implications for diagnosis and treatment EA Sweet-Cordero, JA Biegel Science 363 (6432), 1170-1175, 2019 | 199 | 2019 |
| Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models S Vicent, R Chen, LC Sayles, C Lin, RG Walker, AK Gillespie, ... The Journal of clinical investigation 120 (11), 3940-3952, 2010 | 164 | 2010 |
| A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma R Chen, P Khatri, PK Mazur, M Polin, Y Zheng, D Vaka, CD Hoang, ... Cancer research 74 (10), 2892-2902, 2014 | 162 | 2014 |
| A rare population of CD24+ ITGB4+ Notchhi cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal Y Zheng, CC de la Cruz, LC Sayles, C Alleyne-Chin, D Vaka, TD Knaak, ... Cancer cell 24 (1), 59-74, 2013 | 161 | 2013 |
| Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis CH Chuang, PG Greenside, ZN Rogers, JJ Brady, D Yang, RK Ma, ... Nature medicine 23 (3), 291-300, 2017 | 159 | 2017 |
| HIF-2α deletion promotes Kras-driven lung tumor development J Mazumdar, MM Hickey, DK Pant, AC Durham, A Sweet-Cordero, ... Proceedings of the National Academy of Sciences 107 (32), 14182-14187, 2010 | 157 | 2010 |
| An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer A Vallejo, N Perurena, E Guruceaga, PK Mazur, S Martinez-Canarias, ... Nature communications 8 (1), 14294, 2017 | 150 | 2017 |
| Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for Clcf1 and Il-6 in non–small cell lung cancer in vivo S Vicent, LC Sayles, D Vaka, P Khatri, O Gevaert, R Chen, Y Zheng, ... Cancer research 72 (22), 5744-5756, 2012 | 136 | 2012 |
| Hypoxia in models of lung cancer: implications for targeted therapeutics EE Graves, M Vilalta, IK Cecic, JT Erler, PT Tran, D Felsher, L Sayles, ... Clinical Cancer Research 16 (19), 4843-4852, 2010 | 106 | 2010 |
| Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group RD Roberts, MM Lizardo, DR Reed, P Hingorani, J Glover, ... Cancer 125 (20), 3514-3525, 2019 | 104 | 2019 |
| An Arntl2-driven secretome enables lung adenocarcinoma metastatic self-sufficiency JJ Brady, CH Chuang, PG Greenside, ZN Rogers, CW Murray, ... Cancer cell 29 (5), 697-710, 2016 | 97 | 2016 |
| Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis MM Howarth, D Simpson, SP Ngok, B Nieves, R Chen, Z Siprashvili, ... The Journal of clinical investigation 124 (12), 5275-5290, 2014 | 96 | 2014 |
| Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model TZ Minas, D Surdez, T Javaheri, M Tanaka, M Howarth, HJ Kang, J Han, ... Oncotarget 8 (21), 34141, 2017 | 93 | 2017 |
