| How the ageing microenvironment influences tumour progression M Fane, AT Weeraratna Nature Reviews Cancer 20 (2), 89-106, 2020 | 489 | 2020 |
| Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility A Kaur, BL Ecker, SM Douglass, CH Kugel III, MR Webster, FV Almeida, ... Cancer discovery 9 (1), 64-81, 2019 | 298 | 2019 |
| Age correlates with response to anti-PD1, reflecting age-related differences in intratumoral effector and regulatory T-cell populations CH Kugel III, SM Douglass, MR Webster, A Kaur, Q Liu, X Yin, SA Weiss, ... Clinical Cancer Research 24 (21), 5347-5356, 2018 | 297 | 2018 |
| Age-related changes in HAPLN1 increase lymphatic permeability and affect routes of melanoma metastasis BL Ecker, A Kaur, SM Douglass, MR Webster, FV Almeida, GE Marino, ... Cancer discovery 9 (1), 82-95, 2019 | 113 | 2019 |
| Changes in aged fibroblast lipid metabolism induce age-dependent melanoma cell resistance to targeted therapy via the fatty acid transporter FATP2 GM Alicea, VW Rebecca, AR Goldman, ME Fane, SM Douglass, ... Cancer discovery 10 (9), 1282-1295, 2020 | 87 | 2020 |
| NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF ME Fane, Y Chhabra, DEJ Hollingsworth, JL Simmons, L Spoerri, TG Oh, ... EBioMedicine 16, 63-75, 2017 | 84 | 2017 |
| Stromal changes in the aged lung induce an emergence from melanoma dormancy ME Fane, Y Chhabra, GM Alicea, DA Maranto, SM Douglass, MR Webster, ... Nature 606 (7913), 396-405, 2022 | 81 | 2022 |
| P in1 promotes neuronal death in stroke by stabilizing N otch intracellular domain SH Baik, M Fane, JH Park, YL Cheng, D Yang‐Wei Fann, UJ Yun, Y Choi, ... Annals of neurology 77 (3), 504-516, 2015 | 69 | 2015 |
| BRN 2, a POU erful driver of melanoma phenotype switching and metastasis ME Fane, Y Chhabra, AG Smith, RA Sturm Pigment Cell & Melanoma Research 32 (1), 9-24, 2019 | 62 | 2019 |
| Paradoxical role for wild-type p53 in driving therapy resistance in melanoma MR Webster, ME Fane, GM Alicea, S Basu, AV Kossenkov, GE Marino, ... Molecular cell 77 (3), 633-644. e5, 2020 | 60 | 2020 |
| Nuclear factor one transcription factors as epigenetic regulators in cancer M Fane, L Harris, AG Smith, M Piper International Journal of Cancer 140 (12), 2634-2641, 2017 | 56 | 2017 |
| Genetic screening for single-cell variability modulators driving therapy resistance EA Torre, E Arai, S Bayatpour, CL Jiang, LE Beck, BL Emert, SM Shaffer, ... Nature genetics 53 (1), 76-85, 2021 | 55 | 2021 |
| Bad company: Microenvironmentally mediated resistance to targeted therapy in melanoma FV Almeida, SM Douglass, ME Fane, AT Weeraratna Pigment cell & melanoma research 32 (2), 237-247, 2019 | 45 | 2019 |
| Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells Y Goyal, GT Busch, M Pillai, J Li, RH Boe, EI Grody, M Chelvanambi, ... Nature 620 (7974), 651-659, 2023 | 42 | 2023 |
| Genetic variation in IRF 4 expression modulates growth characteristics, tyrosinase expression and interferon‐gamma response in melanocytic cells Y Chhabra, HXL Yong, ME Fane, A Soogrim, W Lim, DN Mahiuddin, ... Pigment cell & melanoma research 31 (1), 51-63, 2018 | 25 | 2018 |
| Pre-determined diversity in resistant fates emerges from homogenous cells after anti-cancer drug treatment Y Goyal, IP Dardani, GT Busch, B Emert, D Fingerman, A Kaur, N Jain, ... BioRxiv, 2021.12. 08.471833, 2021 | 23 | 2021 |
| ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ I Dardani, BL Emert, Y Goyal, CL Jiang, A Kaur, J Lee, SH Rouhanifard, ... Nature methods 19 (11), 1403-1410, 2022 | 22 | 2022 |
| sFRP2 supersedes VEGF as an age-related driver of angiogenesis in melanoma, affecting response to anti-VEGF therapy in older patients ME Fane, BL Ecker, A Kaur, GE Marino, GM Alicea, SM Douglass, ... Clinical Cancer Research 26 (21), 5709-5719, 2020 | 21 | 2020 |
| Normal aging and its role in cancer metastasis M Fane, AT Weeraratna Cold Spring Harbor Perspectives in Medicine 10 (9), a037341, 2020 | 19 | 2020 |
| Age-related changes in HAPLN1 increase lymphatic permeability and affect routes of melanoma metastasis. Cancer Discov. 2019; 9: 82–95. doi: 10.1158/2159-8290 BL Ecker, A Kaur, SM Douglass, MR Webster, FV Almeida, GE Marino, ... CD-18-0168.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 19 | |
Ashani WeeraratnaBloomberg Distinguished Professor of Cancer BiologyVerified email at jhu.edu
