| Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells J Kath, W Du, A Pruene, T Braun, B Thommandru, R Turk, ML Sturgeon, ... Molecular Therapy-Methods & Clinical Development 25, 311-330, 2022 | 40* | 2022 |
| Association between subcutaneous adipose tissue inflammation, insulin resistance, and calorie restriction in obese females J Sbierski-Kind, K Mai, J Kath, A Jurisch, M Streitz, L Kuchenbecker, ... The Journal of Immunology 205 (1), 45-55, 2020 | 21 | 2020 |
| Distinct housing conditions reveal a major impact of adaptive immunity on the course of obesity-induced type 2 diabetes J Sbierski-Kind, J Kath, S Brachs, M Streitz, MG Von Herrath, AA Kühl, ... Frontiers in immunology 9, 1069, 2018 | 18 | 2018 |
| Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells V Glaser, C Flugel, J Kath, W Du, V Drosdek, C Franke, M Stein, A Pruß, ... Genome Biology 24 (1), 89, 2023 | 14 | 2023 |
| Non-viral TRAC-knocked-in CD19KICAR-T and gp350KICAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV infection: In vivo cellular dynamics … T Braun, A Pruene, M Darguzyte, AF Vom Stein, PH Nguyen, DL Wagner, ... Frontiers in Immunology 14, 1086433, 2023 | 5 | 2023 |
| CAR NK-92 cell–mediated depletion of residual TCR+ cells for ultrapure allogeneic TCR-deleted CAR T-cell products J Kath, W Du, S Martini, M Elsallab, C Franke, L Hartmann, V Drosdek, ... Blood Advances 7 (15), 4124-4134, 2023 | 3 | 2023 |
| IRAK1 Duplication in MECP2 Duplication Syndrome Does Not Increase Canonical NF-κB–Induced Inflammation I Gottschalk, U Kölsch, DL Wagner, J Kath, S Martini, R Krüger, A Puel, ... Journal of Clinical Immunology 43 (2), 421-439, 2023 | 2 | 2023 |
| Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells J Kath, C Franke, V Drosdek, W Du, V Glaser, C Fuster-Garcia, M Stein, ... Blood Journal, blood. 2023020973, 2024 | 1 | 2024 |
| White adipose tissue inflammation is not attenuated by short-term calorie restriction in obese humans J Sbierski-Kind, K Mai, J Kath, A Jurisch, M Streitz, L Kuchenbecker, ... medRxiv, 19005934, 2019 | 1 | 2019 |
| Gene editing of CD3 epsilon gene to redirect regulatory T cells for adoptive T cell transfer W Du, F Noyan, O McCallion, V Drosdek, J Kath, V Glaser, ... bioRxiv, 2024.03. 18.584896, 2024 | | 2024 |
| Reprogramming immune cells by targeted integration of zeta-deficient chimeric antigen receptor transgenes DL Wagner, JC Kath, M Schmück-henneresse, HD Volk, P Reinke US Patent App. 18/268,906, 2023 | | 2023 |
| PREVENTING TRANSLOCATIONS IN MULTIPLEX-EDITED ALLOGENEIC CAR T CELLS BY COMBINING DIFFERENT CRISPR NUCLEASES FOR SIMULTANEOUS KNOCK-IN AND BASE EDITING V Glaser, C Flugel, J Kath, W Du, V Drosdek, C Franke, M Stein, A Pruss, ... HUMAN GENE THERAPY 34 (21-22), A26-A26, 2023 | | 2023 |
| Matching or genetic engineering of HLA Class I and II facilitates successful allogeneic'off-the-shelf'regulatory T cell therapy O McCallion, W Du, V Glaser, K Milward, C Franke, J Kath, M Valkov, ... bioRxiv, 2023.08. 06.551956, 2023 | | 2023 |
| Complex gene editing of T cells without translocations V Glaser, C Flugel, J Kath, W Du, V Drosdek, C Franke, ... HUMAN GENE THERAPY 33 (23-24), A137-A137, 2022 | | 2022 |
| CD247 (CD3 zeta) gene editing as a novel platform technology for off-the-shelf Chimeric Antigen Receptor reprogrammed immune cells J Kath, W Du, C Franke, V Drosdek, V Glaser, M Stein, T Zittel, ... HUMAN GENE THERAPY 33 (23-24), A125-A126, 2022 | | 2022 |
| HER2/neu-specific CAR expression level in human T cells dictates antigen-independent differentiation during in vitro expansion V Drosdek, J Kath, H Abken, DL Wagner HUMAN GENE THERAPY 33 (23-24), A126-A126, 2022 | | 2022 |
| Generation of CD19-specific CAR NK cells using virus-free CRISPR-Cas9 gene editing C Franke, J Kath, V Glaser, W Du, V Drosdek, DL Wagner HUMAN GENE THERAPY 33 (23-24), A128-A128, 2022 | | 2022 |
| Improved non-viral CAR-reprogramming of human T cells using CRISPR-Cas and double-stranded DNA J Kath, W Du, V Glaser, B Thommandru, R Turk, M Stein, T Zittel, ... HUMAN GENE THERAPY 32 (19-20), A4-A4, 2021 | | 2021 |
| An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes J Sbierski-Kind, K Schmidt-Bleek, M Streitz, J Kath, J Spranger, HD Volk JoVE (Journal of Visualized Experiments), e59470, 2019 | | 2019 |
