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Hans-Ulrich Klein
Hans-Ulrich Klein
Columbia University Medical Center
Verified email at columbia.edu - Homepage
Title
Cited by
Cited by
Year
Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
T Haferlach, Y Nagata, V Grossmann, Y Okuno, U Bacher, G Nagae, ...
Leukemia 28 (2), 241-247, 2014
16432014
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
T Schenk, WC Chen, S Göllner, L Howell, L Jin, K Hebestreit, HU Klein, ...
Nature medicine 18 (4), 605-611, 2012
7002012
Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms
C Polprasert, I Schulze, MA Sekeres, H Makishima, B Przychodzen, ...
Cancer cell 27 (5), 658-670, 2015
4322015
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome
B Ng, CC White, HU Klein, SK Sieberts, C McCabe, E Patrick, J Xu, L Yu, ...
Nature neuroscience 20 (10), 1418-1426, 2017
3932017
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease
S Mostafavi, C Gaiteri, SE Sullivan, CC White, S Tasaki, J Xu, M Taga, ...
Nature Neuroscience 21 (6), 811, 2018
3912018
A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research
PL De Jager, Y Ma, C McCabe, J Xu, BN Vardarajan, D Felsky, HU Klein, ...
Scientific data 5 (1), 1-13, 2018
3502018
Next-generation sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in …
A Kohlmann, V Grossmann, HU Klein, S Schindela, T Weiss, B Kazak, ...
Journal of clinical oncology 28 (24), 3858-3865, 2010
3492010
Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype
V Grossmann, E Tiacci, AB Holmes, A Kohlmann, MP Martelli, W Kern, ...
Blood, The Journal of the American Society of Hematology 118 (23), 6153-6163, 2011
2832011
Detection of significantly differentially methylated regions in targeted bisulfite sequencing data
K Hebestreit, M Dugas, HU Klein
Bioinformatics 29 (13), 1647-1653, 2013
2482013
Tau activates transposable elements in Alzheimer’s disease
C Guo, HH Jeong, YC Hsieh, HU Klein, DA Bennett, PL De Jager, Z Liu, ...
Cell Reports 23 (10), 2874-2880, 2018
2452018
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia
S Göllner, T Oellerich, S Agrawal-Singh, T Schenk, HU Klein, C Rohde, ...
Nature medicine 23 (1), 69-78, 2017
2222017
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models
YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ...
Cell reports 32 (2), 2020
2052020
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer’s human brains
HU Klein, C McCabe, E Gjoneska, SE Sullivan, BJ Kaskow, A Tang, ...
Nature neuroscience 22 (1), 37-46, 2019
1942019
Novel Alzheimer disease risk loci and pathways in African American individuals using the African genome resources panel: a meta-analysis
BW Kunkle, M Schmidt, HU Klein, AC Naj, KL Hamilton-Nelson, ...
JAMA neurology 78 (1), 102-113, 2021
1632021
Multilineage dysplasia (MLD) in acute myeloid leukemia (AML) correlates with MDS-related cytogenetic abnormalities and a prior history of MDS or MDS/MPN but has no independent …
M Miesner, C Haferlach, U Bacher, T Weiss, K Macijewski, A Kohlmann, ...
Blood, The Journal of the American Society of Hematology 116 (15), 2742-2751, 2010
1482010
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia
F Zhou, Y Liu, C Rohde, C Pauli, D Gerloff, M Köhn, D Misiak, N Bäumer, ...
Nature cell biology 19 (7), 844-855, 2017
1422017
Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1)
B Falini, K Macijewski, T Weiss, U Bacher, S Schnittger, W Kern, ...
Blood, The Journal of the American Society of Hematology 115 (18), 3776-3786, 2010
1422010
The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium …
A Kohlmann, HU Klein, S Weissmann, S Bresolin, T Chaplin, H Cuppens, ...
Leukemia 25 (12), 1840-1848, 2011
1372011
Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells
E Bolton-Gillespie, M Schemionek, HU Klein, S Flis, G Hoser, T Lange, ...
Blood, The Journal of the American Society of Hematology 121 (20), 4175-4183, 2013
1332013
AML with translocation t (8; 16)(p11; p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features
T Haferlach, A Kohlmann, HU Klein, C Ruckert, M Dugas, PM Williams, ...
Leukemia 23 (5), 934-943, 2009
1252009
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