Alterations in cholesterol metabolism as a risk factor for developing Alzheimer’s disease: Potential novel targets for treatment R Loera-Valencia, J Goikolea, C Parrado-Fernandez, P Merino-Serrais, ... The Journal of steroid biochemistry and molecular biology 190, 104-114, 2019 | 191 | 2019 |
Cross-disease analysis of Alzheimer’s disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases L Caberlotto, TP Nguyen, M Lauria, C Priami, R Rimondini, S Maioli, ... Scientific reports 9 (1), 3965, 2019 | 82 | 2019 |
27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation MAM Ismail, L Mateos, S Maioli, P Merino-Serrais, Z Ali, M Lodeiro, ... Journal of Experimental Medicine 214 (3), 699-717, 2017 | 75 | 2017 |
The composition of polypharmacy: a register-based study of Swedes aged 75 years and older JW Wastesson, A Cedazo Minguez, J Fastbom, S Maioli, K Johnell PloS one 13 (3), e0194892, 2018 | 72 | 2018 |
Aggregation of the inflammatory S100A8 precedes Aβ plaque formation in transgenic APP mice: positive feedback for S100A8 and Aβ productions M Lodeiro, E Puerta, MAM Ismail, P Rodriguez-Rodriguez, A Rönnbäck, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017 | 71 | 2017 |
Is it possible to improve memory function by upregulation of the cholesterol 24S-hydroxylase (CYP46A1) in the brain? S Maioli, A Båvner, Z Ali, M Heverin, MAM Ismail, E Puerta, M Olin, ... PloS one 8 (7), e68534, 2013 | 70 | 2013 |
Estrogen receptors and the aging brain S Maioli, K Leander, P Nilsson, I Nalvarte Essays in Biochemistry 65 (6), 913-925, 2021 | 69 | 2021 |
27-hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice M Heverin, S Maioli, T Pham, L Mateos, E Camporesi, Z Ali, B Winblad, ... Behavioural brain research 278, 356-359, 2015 | 69 | 2015 |
Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease S Maioli, M Lodeiro, P Merino‐Serrais, F Falahati, W Khan, E Puerta, ... Aging cell 14 (1), 122-129, 2015 | 68 | 2015 |
27-Hydroxycholesterol induces aberrant morphology and synaptic dysfunction in hippocampal neurons P Merino-Serrais, R Loera-Valencia, P Rodriguez-Rodriguez, ... Cerebral cortex 29 (1), 429-446, 2019 | 60 | 2019 |
Combination of apolipoprotein E4 and high carbohydrate diet reduces hippocampal BDNF and arc levels and impairs memory in young mice S Maioli, E Puerta, P Merino-Serrais, L Fusari, F Gil-Bea, R Rimondini, ... Journal of Alzheimer's Disease 32 (2), 341-355, 2012 | 57 | 2012 |
Brain renin–angiotensin system as novel and potential therapeutic target for Alzheimer’s disease R Loera-Valencia, F Eroli, S Garcia-Ptacek, S Maioli International journal of molecular sciences 22 (18), 10139, 2021 | 42 | 2021 |
Apolipoprotein E4 elicits lysosomal cathepsin D release, decreased thioredoxin-1 levels, and apoptosis T Persson, F Lattanzio, J Calvo-Garrido, R Rimondini, M Rubio-Rodrigo, ... Journal of Alzheimer's Disease 56 (2), 601-617, 2017 | 40 | 2017 |
Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in AppNL-G-F/NL-G-F mice C Emre, LE Arroyo-García, KV Do, B Jun, M Ohshima, SG Alcalde, ... Communications biology 5 (1), 245, 2022 | 33 | 2022 |
Hypercholesterolemia and 27-hydroxycholesterol increase S100A8 and RAGE expression in the brain: a link between cholesterol, Alarmins, and neurodegeneration R Loera-Valencia, MAM Ismail, J Goikolea, M Lodeiro, L Mateos, ... Molecular neurobiology 58 (12), 6063-6076, 2021 | 24 | 2021 |
Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations J Wanngren, P Lara, K Öjemalm, S Maioli, N Moradi, L Chen, ... FEBS open bio 4, 393-406, 2014 | 23 | 2014 |
5-HT1B and other related serotonergic proteins are altered in APPswe mutation W Tajeddinn, T Persson, S Maioli, J Calvo-Garrido, C Parrado-Fernandez, ... Neuroscience Letters 594, 137-143, 2015 | 21 | 2015 |
Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD J Goikolea, G Gerenu, M Daniilidou, F Mangialasche, P Mecocci, ... Alzheimer's Research & Therapy 14 (1), 37, 2022 | 14 | 2022 |
Chronic polypharmacy impairs explorative behavior and reduces synaptic functions in young adult mice F Eroli, K Johnell, ML Leal, C Adamo, S Hilmer, JW Wastesson, ... Aging (Albany NY) 12 (11), 10147, 2020 | 13 | 2020 |
Pharmacological modulations of the serotonergic system in a cell-model of familial Alzheimer’s disease W Tajeddinn, T Persson, J Calvo-Garrido, M Seed Ahmed, S Maioli, ... Journal of Alzheimer's Disease 53 (1), 349-361, 2016 | 11 | 2016 |