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Melissa Spencer
Melissa Spencer
Professor of Neurology, David Geffen School of Medicine at UCLA
Verified email at mednet.ucla.edu
Title
Cited by
Cited by
Year
A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice
M Wehling, MJ Spencer, JG Tidball
The Journal of cell biology 155 (1), 123-132, 2001
6392001
Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy.
WJ Chang, ST Iannaccone, KS Lau, BS Masters, TJ Mccabe, K Mcmillan, ...
Proceedings of the National Academy of Sciences 93 (17), 9142-9147, 1996
4271996
A single CRISPR-Cas9 deletion strategy that targets the majority of DMD patients restores dystrophin function in hiPSC-derived muscle cells
CS Young, MR Hicks, NV Ermolova, H Nakano, M Jan, S Younesi, ...
Cell stem cell 18 (4), 533-540, 2016
4042016
Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-β
SA Vetrone, E Montecino-Rodriguez, E Kudryashova, I Kramerova, ...
The Journal of clinical investigation 119 (6), 1583-1594, 2009
3302009
Helper (CD4+) and cytotoxic (CD8+) T cells promote the pathology of dystrophin-deficient muscle
MJ Spencer, E Montecino-Rodriguez, K Dorshkind, JG Tidball
Clinical immunology 98 (2), 235-243, 2001
3262001
Apoptosis precedes necrosis of dystrophin-deficient muscle
JG Tidball, DE Albrecht, BE Lokensgard, MJ Spencer
Journal of cell science 108 (6), 2197-2204, 1995
2901995
Mechanical loading regulates NOS expression and activity in developing and adult skeletal muscle
JG Tidball, E Lavergne, KS Lau, MJ Spencer, JT Stull, M Wehling
American Journal of Physiology-Cell Physiology 275 (1), C260-C266, 1998
2801998
Expression of a calpastatin transgene slows muscle wasting and obviates changes in myosin isoform expression during murine muscle disuse
JG Tidball, MJ Spencer
The Journal of physiology 545 (3), 819-828, 2002
2742002
Calpains are activated in necrotic fibers from mdx dystrophic mice
MJ Spencer, DE Croall, JG Tidball
Journal of Biological Chemistry 270 (18), 10909-10914, 1995
2741995
Regulatory T cells suppress muscle inflammation and injury in muscular dystrophy
SA Villalta, W Rosenthal, L Martinez, A Kaur, T Sparwasser, JG Tidball, ...
Science translational medicine 6 (258), 258ra142-258ra142, 2014
2562014
Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin
E Kudryashova, D Kudryashov, I Kramerova, MJ Spencer
Journal of molecular biology 354 (2), 413-424, 2005
2482005
Do immune cells promote the pathology of dystrophin-deficient myopathies?
MJ Spencer, JG Tidball
Neuromuscular Disorders 11 (6-7), 556-564, 2001
2402001
Null mutation of calpain 3 (p94) in mice causes abnormal sarcomere formation in vivo and in vitro
I Kramerova, E Kudryashova, JG Tidball, MJ Spencer
Human molecular genetics 13 (13), 1373-1388, 2004
2372004
Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology
MJ Spencer, RL Mellgren
Human molecular genetics 11 (21), 2645-2655, 2002
2342002
Myonuclear apoptosis in dystrophic mdx muscle occurs by perforin-mediated cytotoxicity.
MJ Spencer, CM Walsh, KA Dorshkind, EM Rodriguez, JG Tidball
The Journal of clinical investigation 99 (11), 2745-2751, 1997
2121997
Calpain 3 participates in sarcomere remodeling by acting upstream of the ubiquitin–proteasome pathway
I Kramerova, E Kudryashova, G Venkatraman, MJ Spencer
Human Molecular Genetics 14 (15), 2125-2134, 2005
1922005
Calpains and muscular dystrophies
JG Tidball, MJ Spencer
The international journal of biochemistry & cell biology 32 (1), 1-5, 2000
1852000
Calpain 3, the “gatekeeper” of proper sarcomere assembly, turnover and maintenance
JS Beckmann, M Spencer
Neuromuscular Disorders 18 (12), 913-921, 2008
1752008
ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs
MR Hicks, J Hiserodt, K Paras, W Fujiwara, A Eskin, M Jan, H Xi, ...
Nature cell biology 20 (1), 46-57, 2018
1652018
Structure, organization, and expression of the rat cardiac myosin light chain-2 gene: identification of a 250-base pair fragment which confers cardiac-specific expression
SA Henderson, M Spencer, A Sen, C Kumar, MAQ Siddiqui, KR Chien
Journal of Biological Chemistry 264 (30), 18142-18148, 1989
1621989
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