Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity SS Ng, KL Kavanagh, MA McDonough, D Butler, ES Pilka, BMR Lienard, ... Nature 448 (7149), 87-91, 2007 | 348 | 2007 |
Closing the cohesin ring: structure and function of its Smc3-kleisin interface TG Gligoris, JC Scheinost, F Bürmann, N Petela, KL Chan, P Uluocak, ... Science 346 (6212), 963-967, 2014 | 287 | 2014 |
The cohesin ring uses its hinge to organize DNA using non-topological as well as topological mechanisms M Srinivasan, JC Scheinost, NJ Petela, TG Gligoris, M Wissler, S Ogushi, ... Cell 173 (6), 1508-1519. e18, 2018 | 135 | 2018 |
Releasing activity disengages cohesin’s Smc3/Scc1 interface in a process blocked by acetylation F Beckouet, M Srinivasan, MB Roig, KL Chan, JC Scheinost, P Batty, B Hu, ... Molecular cell 61 (4), 563-574, 2016 | 129 | 2016 |
Sister DNA entrapment between juxtaposed smc heads and kleisin of the cohesin complex C Chapard, R Jones, T van Oepen, JC Scheinost, K Nasmyth Molecular cell 75 (2), 224-237. e5, 2019 | 68 | 2019 |
Adduction of cholesterol 5, 6-secosterol aldehyde to membrane-bound myelin basic protein exposes an immunodominant epitope NK Cygan, JC Scheinost, TD Butters, P Wentworth Jr Biochemistry 50 (12), 2092-2100, 2011 | 38 | 2011 |
Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 M Srinivasan, NJ Petela, JC Scheinost, J Collier, M Voulgaris, M B Roig, ... Elife 8, e44736, 2019 | 35 | 2019 |
Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 M Srinivasan, NJ Petela, JC Scheinost, J Collier, M Voulgaris, M B Roig, ... Elife 8, e44736, 2019 | 35 | 2019 |
Cholesterol seco-sterol-induced aggregation of methylated amyloid-beta peptides--insights into aldehyde-initiated fibrillization of amyloid-beta JC Scheinost, H Wang, GE Boldt, J Offer, P Wentworth Angew Chem Int Ed Engl 47 (21), 3919-3922, 2008 | 28 | 2008 |
The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein T Whitfield, AJ Miles, JC Scheinost, J Offer, P Wentworth Jr, RA Dwek, ... Molecular Membrane Biology 28 (5), 254-264, 2011 | 24 | 2011 |
Bü rmann F, Petela N, Chan KL, Uluocak P, Beckouë t F, Gruber S, Nasmyth K, Lowe J. 2014. Closing the cohesin ring: structure and function of its Smc3-kleisin interface TG Gligoris, JC Scheinost Science 346, 963-967, 0 | 16 | |
Cholesterol secosterol adduction inhibits the misfolding of a mutant prion protein fragment that induces neurodegeneration JC Scheinost, DP Witter, GE Boldt, J Offer, P Wentworth Angewandte Chemie International Edition 48 (50), 9469-9472, 2009 | 14 | 2009 |
The topology of DNA entrapment by cohesin rings C Chapard, R Jones, T van Oepen, JC Scheinost, K Nasmyth bioRxiv, 495762, 2018 | 4 | 2018 |
Covalent attachment of peptides and biological molecules to luminescent semiconductor nanocrystals HM Mattoussi, PE Dawson, HT Uyeda, IL Medintz, JC Scheinost US Patent App. 12/606,766, 2011 | 4 | 2011 |
Role of oxidative stress in protein misfolding and/or amyloid formation JC Scheinost, DP Witter, GE Boldt, P Wentworth Protein Misfolding Diseases: Current and Emerging Principles and Therapies …, 2010 | 4 | 2010 |
Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 but is unnecessary during S phase for establishing cohesion M Srinivasan, NJ Petela, JC Scheinost, J Collier, M Voulgaris, ... bioRxiv, 513960, 2019 | 1 | 2019 |
Protein Misfolding and Disease JC Scheinost, GE Boldt, P Wentworth Chemical Biology: Approaches to Drug Discovery and Development to Targeting …, 2012 | 1 | 2012 |
Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 S Madhusudhan, NJ Petela, JC Scheinost, J Collier, V Menelaos, ... eLife 8, 2019 | | 2019 |
Structurally Guided In Vivo Crosslinking JC Scheinost, TG Gligoris Protein Complex Assembly: Methods and Protocols, 123-132, 2018 | | 2018 |
PMC3215938. P Savitsky, O Gileadi, F von Delft, NR Rose, J Offer, JC Scheinost, ... Biochemistry 52 (24), 4168-83, 2013 | | 2013 |