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Ishna Mistry
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Clinical advances of hypoxia-activated prodrugs in combination with radiation therapy
IN Mistry, M Thomas, EDD Calder, SJ Conway, EM Hammond
International Journal of Radiation Oncology* Biology* Physics 98 (5), 1183-1196, 2017
1462017
CYP450 enzymes effect oxygen-dependent reduction of azide-based fluorogenic dyes
LJ O’Connor, IN Mistry, SL Collins, LK Folkes, G Brown, SJ Conway, ...
ACS Central Science 3 (1), 20-30, 2017
742017
Fluorescent transmembrane anion transporters: shedding light on anionophoric activity in cells
SN Berry, V Soto-Cerrato, ENW Howe, HJ Clarke, I Mistry, A Tavassoli, ...
Chemical Science 7 (8), 5069-5077, 2016
572016
Hypoxia drives the assembly of the multienzyme purinosome complex
C Doigneaux, AM Pedley, IN Mistry, M Papayova, SJ Benkovic, ...
Journal of Biological Chemistry 295 (28), 9551-9566, 2020
322020
Reprogramming the transcriptional response to hypoxia with a chromosomally encoded cyclic peptide HIF-1 inhibitor
IN Mistry, A Tavassoli
ACS Synthetic Biology 6 (3), 518-527, 2017
292017
BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability
LE Jennings, M Schiedel, DS Hewings, S Picaud, CMC Laurin, PA Bruno, ...
Bioorganic & Medicinal Chemistry 26 (11), 2937-2957, 2018
272018
Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor
A Skwarska, EDD Calder, D Sneddon, H Bolland, ML Odyniec, IN Mistry, ...
Cell chemical biology 28 (9), 1258-1270. e13, 2021
252021
Hypoxia-activated pro-drugs of the KDAC inhibitor Vorinostat (SAHA)
EDD Calder, A Skwarska, D Sneddon, LK Folkes, IN Mistry, SJ Conway, ...
Tetrahedron, 131170, 2020
202020
Post-translational control of protein function with light using a LOV-intein fusion protein
DC Jones, IN Mistry, A Tavassoli
Molecular BioSystems 12 (4), 1388-1393, 2016
152016
Probing the epigenetic regulation of HIF-1α transcription in developing tissue
IN Mistry, PJS Smith, DI Wilson, A Tavassoli
Molecular BioSystems 11 (10), 2780-2785, 2015
82015
The design, synthesis, and evaluation of hypoxia-activated prodrugs of the KDAC inhibitor panobinostat
E Calder, A Skwarska, D Sneddon, L Folkes, IN Mistry, EM Hammond, ...
2020
Dataset for: Hypoxia drives the assembly of the multi-enzyme purinosome complex
C Doigneaux, A Pedley, IN Mistry, M Papayova, S Benkovic, A Tavassoli
University of Southampton, 2020
2020
Hypoxia-activated prodrugs of the KDAC inhibitor panobinostat
E Calder, I Mistry, E Hammond, S Conway
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Reprogramming the cellular response to hypoxia
I Mistry
University of Southampton, 2016
2016
Dataset for Fluorescent transmembrane anion transporters: shedding light on anionophoric activity in cells
S Berry, V Soto-Cerrato, ENW HOWE, H Clarke, I Mistry, A Tavassoli, ...
University of Southampton, 2016
2016
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