Palmitic acid is an intracellular signaling molecule involved in disease development S Fatima, X Hu, RH Gong, C Huang, M Chen, HLX Wong, Z Bian, ... Cellular and Molecular Life Sciences 76, 2547-2557, 2019 | 121 | 2019 |
Saturated long-chain fatty acid-producing bacteria contribute to enhanced colonic motility in rats L Zhao, Y Huang, L Lu, W Yang, T Huang, Z Lin, C Lin, H Kwan, ... Microbiome 6, 1-16, 2018 | 105 | 2018 |
MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis HLX Wong, G Jin, R Cao, S Zhang, Y Cao, Z Zhou Nature communications 7 (1), 10824, 2016 | 82 | 2016 |
MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis KM Chan, HLX Wong, G Jin, B Liu, R Cao, Y Cao, K Lehti, K Tryggvason, ... Developmental cell 22 (6), 1176-1190, 2012 | 82 | 2012 |
Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials DT Rubin, I Dotan, A DuVall, Y Bouhnik, G Radford-Smith, PDR Higgins, ... The lancet Gastroenterology & hepatology 7 (1), 17-27, 2022 | 71 | 2022 |
MT1‐MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B‐cell development G Jin, F Zhang, KM Chan, HL Xavier Wong, B Liu, KSE Cheah, X Liu, ... The EMBO journal 30 (11), 2281-2293, 2011 | 60 | 2011 |
Safety and efficacy of non‐steroidal anti‐inflammatory drugs to reduce ileus after colorectal surgery EuroSurg Collaborative, SJ Chapman, D Clerc, R Blanco‐Colino, A Otto, ... British Journal of Surgery 107 (2), e161-e169, 2020 | 55 | 2020 |
Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling HLX Wong, H Qin, SW Tsang, X Zuo, S Che, CFW Chow, X Li, H Xiao, ... Nature Communications 10 (1), 1745, 2019 | 53 | 2019 |
High-fat diet feeding and palmitic acid increase CRC growth in β2AR-dependent manner S Fatima, X Hu, C Huang, W Zhang, J Cai, M Huang, RH Gong, M Chen, ... Cell death & disease 10 (10), 711, 2019 | 46 | 2019 |
Comparison of range of motion after standard and high-flexion posterior stabilised total knee replacement FY Ng, HL Wong, WP Yau, KY Chiu, WM Tang International orthopaedics 32, 795-798, 2008 | 40 | 2008 |
Gut-microbial metabolites, probiotics and their roles in type 2 diabetes L Zhai, J Wu, YY Lam, HY Kwan, ZX Bian, HLX Wong International Journal of Molecular Sciences 22 (23), 12846, 2021 | 39 | 2021 |
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis L Zhai, C Huang, Z Ning, Y Zhang, M Zhuang, W Yang, X Wang, J Wang, ... Cell Host & Microbe 31 (1), 33-44. e5, 2023 | 34 | 2023 |
Baicalein is a novel TLR4‐targeting therapeutics agent that inhibits TLR4/HIF‐1α/VEGF signaling pathway in colorectal cancer M Chen, K Zhong, J Tan, M Meng, CM Liu, B Chen, C Huang, HLX Wong, ... Clinical and translational medicine 11 (11), 2021 | 28 | 2021 |
When MT1-MMP meets ADAMs HLX Wong, R Cao, G Jin, K Ming Chan, Y Cao, Z Zhou Cell Cycle 11 (15), 2793-2798, 2012 | 27 | 2012 |
Berberine suppresses colonic inflammation in dextran sulfate sodium–induced murine colitis through inhibition of cytosolic phospholipase A2 activity L Zhai, T Huang, H Xiao, P Wu, C Lin, Z Ning, L Zhao, HYA Kwan, X Hu, ... Frontiers in Pharmacology 11, 576496, 2020 | 26 | 2020 |
Signal transducer and activator of transcription-3 drives the high-fat diet-associated prostate cancer growth HY Kwan, B Liu, C Huang, S Fatima, T Su, X Zhao, AHM Ho, Q Han, X Hu, ... Cell death & disease 10 (9), 637, 2019 | 24 | 2019 |
Klotho an autophagy stimulator as a potential therapeutic target for Alzheimer’s disease: A review TY Fung, A Iyaswamy, SG Sreenivasmurthy, S Krishnamoorthi, XJ Guan, ... Biomedicines 10 (3), 705, 2022 | 22 | 2022 |
Body weight regulation via MT1-MMP-mediated cleavage of GFRAL CFW Chow, X Guo, P Asthana, S Zhang, SKK Wong, S Fallah, S Che, ... Nature metabolism 4 (2), 203-212, 2022 | 22 | 2022 |
Safety of hospital discharge before return of bowel function after elective colorectal surgery Journal of British Surgery 107 (5), 552-559, 2020 | 21 | 2020 |
Enterochromaffin cell hyperplasia in the gut: factors, mechanism and therapeutic clues H Qin, HLX Wong, K Zang, X Li, Z Bian Life sciences 239, 116886, 2019 | 20 | 2019 |