|Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3′, 5′-monophosphate|
J Castro, AM Harrington, PA Hughes, CM Martin, P Ge, CM Shea, H Jin, ...
Gastroenterology 145 (6), 1334-1346. e11, 2013
|Necrotic volume increase and the early physiology of necrosis|
LF Barros, T Hermosilla, J Castro
Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2001
|Apoptotic and necrotic blebs in epithelial cells display similar neck diameters but different kinase dependency|
LF Barros, T Kanaseki, R Sabirov, S Morishima, J Castro, CX Bittner, ...
Cell death and differentiation 10 (6), 687, 2003
|Enterochromaffin cells are gut chemosensors that couple to sensory neural pathways|
NW Bellono, JR Bayrer, DB Leitch, J Castro, C Zhang, TA O’Donnell, ...
Cell 170 (1), 185-198. e16, 2017
|Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes|
PA Hughes, AM Harrington, J Castro, T Liebregts, B Adam, DJ Grasby, ...
Gut 62 (10), 1456-1465, 2013
|Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain|
JD Osteen, V Herzig, J Gilchrist, JJ Emrick, C Zhang, X Wang, J Castro, ...
Nature 534 (7608), 494, 2016
|A novel role for TRPM8 in visceral afferent function|
AM Harrington, PA Hughes, CM Martin, J Yang, J Castro, NJ Isaacs, ...
Pain® 152 (7), 1459-1468, 2011
|TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity|
SM Brierley, J Castro, AM Harrington, PA Hughes, AJ Page, GY Rychkov, ...
The Journal of physiology 589 (14), 3575-3593, 2011
|Nonselective cation channels as effectors of free radical–induced rat liver cell necrosis|
LF Barros, A Stutzin, A Calixto, M CATALan, J Castro, C Hetz, ...
Hepatology 33 (1), 114-122, 2001
|Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain|
AD De Araujo, M Mobli, J Castro, AM Harrington, I Vetter, Z Dekan, ...
Nature communications 5, 3165, 2014
|Hyperosmotic shock induces both activation and translocation of glucose transporters in mammalian cells|
FL Barros, K Barnes, JC Ingram, J Castro, OH Porras, SA Baldwin
Pflügers Archiv 442 (4), 614-621, 2001
|Mitochondrial uncoupler FCCP activates proton conductance but does not block store-operated Ca2+ current in liver cells|
MS To, EC Aromataris, J Castro, ML Roberts, GJ Barritt, GY Rychkov
Archives of biochemistry and biophysics 495 (2), 152-158, 2010
|α-Conotoxin Vc1. 1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors|
J Castro, AM Harrington, S Garcia-Caraballo, J Maddern, L Grundy, ...
Gut 66 (6), 1083-1094, 2017
|Ion movements in cell death: from protection to execution.|
LF Barros, J Castro, CX Bittner
Biological research 35 (2), 209-214, 2002
|Phospholipase C-γ1 is required for the activation of store-operated Ca2+ channels in liver cells|
T Litjens, T Nguyen, J Castro, EC Aromataris, L Jones, GJ Barritt, ...
Biochemical Journal 405 (2), 269-276, 2007
|Cytosolic [Ca2+] modulates basal GLUT1 activity and plays a permissive role in its activation by metabolic stress and insulin in rat epithelial cells|
RA Quintanilla, OH Porras, J Castro, LF Barros
Cell calcium 28 (2), 97-106, 2000
|Store-operated Ca2+ channels and Stromal Interaction Molecule 1 (STIM1) are targets for the actions of bile acids on liver cells|
EC Aromataris, J Castro, GY Rychkov, GJ Barritt
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (5), 874-885, 2008
|A cytosolic source of calcium unveiled by hydrogen peroxide with relevance for epithelial cell death|
J Castro, CX Bittner, A Humeres, VP Montecinos, JC Vera, LF Barros
Cell death and differentiation 11 (4), 468, 2004
|Increased κ-opioid receptor expression and function during chronic visceral hypersensitivity|
PA Hughes, J Castro, AM Harrington, N Isaacs, M Moretta, GA Hicks, ...
Gut 63 (7), 1199-1200, 2014
|Apelin targets gut contraction to control glucose metabolism via the brain|
A Fournel, A Drougard, T Duparc, A Marlin, SM Brierley, J Castro, ...
Gut 66 (2), 258-269, 2017