| Enterochromaffin cells are gut chemosensors that couple to sensory neural pathways NW Bellono, JR Bayrer, DB Leitch, J Castro, C Zhang, TA O’Donnell, ... Cell 170 (1), 185-198. e16, 2017 | 691 | 2017 |
| Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3′, 5′-monophosphate J Castro, AM Harrington, PA Hughes, CM Martin, P Ge, CM Shea, H Jin, ... Gastroenterology 145 (6), 1334-1346. e11, 2013 | 283 | 2013 |
| Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain JD Osteen, V Herzig, J Gilchrist, JJ Emrick, C Zhang, X Wang, J Castro, ... Nature 534 (7608), 494-499, 2016 | 276 | 2016 |
| Necrotic volume increase and the early physiology of necrosis LF Barros, T Hermosilla, J Castro Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2001 | 204 | 2001 |
| Apoptotic and necrotic blebs in epithelial cells display similar neck diameters but different kinase dependency LF Barros, T Kanaseki, R Sabirov, S Morishima, J Castro, CX Bittner, ... Cell Death & Differentiation 10 (6), 687-697, 2003 | 198 | 2003 |
| Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes PA Hughes, AM Harrington, J Castro, T Liebregts, B Adam, DJ Grasby, ... Gut 62 (10), 1456-1465, 2013 | 197 | 2013 |
| A novel role for TRPM8 in visceral afferent function AM Harrington, PA Hughes, CM Martin, J Yang, J Castro, NJ Isaacs, ... Pain® 152 (7), 1459-1468, 2011 | 164 | 2011 |
| Pain in endometriosis J Maddern, L Grundy, J Castro, SM Brierley Frontiers in cellular neuroscience 14, 590823, 2020 | 158 | 2020 |
| TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity SM Brierley, J Castro, AM Harrington, PA Hughes, AJ Page, GY Rychkov, ... The Journal of physiology 589 (14), 3575-3593, 2011 | 154 | 2011 |
| Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome NN Jimenez-Vargas, LA Pattison, P Zhao, TM Lieu, R Latorre, DD Jensen, ... Proceedings of the National Academy of Sciences 115 (31), E7438-E7447, 2018 | 149 | 2018 |
| Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain AD De Araujo, M Mobli, J Castro, AM Harrington, I Vetter, Z Dekan, ... Nature communications 5 (1), 3165, 2014 | 132 | 2014 |
| Nonselective cation channels as effectors of free radical-induced rat liver cell necrosis LF Barros, A Stutzin, A Calixto, M CATALan, J Castro, C Hetz, ... Hepatology 33 (1), 114-122, 2001 | 102 | 2001 |
| α-Conotoxin Vc1. 1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors J Castro, AM Harrington, S Garcia-Caraballo, J Maddern, L Grundy, ... Gut 66 (6), 1083-1094, 2017 | 91 | 2017 |
| Apelin targets gut contraction to control glucose metabolism via the brain A Fournel, A Drougard, T Duparc, A Marlin, SM Brierley, J Castro, ... Gut 66 (2), 258-269, 2017 | 89 | 2017 |
| Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1 MC Inserra, MR Israel, A Caldwell, J Castro, JR Deuis, AM Harrington, ... Scientific reports 7 (1), 42810, 2017 | 83 | 2017 |
| Mitochondrial uncoupler FCCP activates proton conductance but does not block store-operated Ca2+ current in liver cells MS To, EC Aromataris, J Castro, ML Roberts, GJ Barritt, GY Rychkov Archives of biochemistry and biophysics 495 (2), 152-158, 2010 | 74 | 2010 |
| Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity J Castro, AM Harrington, TM Lieu, S Garcia-Caraballo, J Maddern, ... JCI insight 4 (20), 2019 | 67 | 2019 |
| Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction L Grundy, AM Harrington, J Castro, S Garcia-Caraballo, A Deiteren, ... JCI insight 3 (19), 2018 | 65 | 2018 |
| Hyperosmotic shock induces both activation and translocation of glucose transporters in mammalian cells FL Barros, K Barnes, JC Ingram, J Castro, OH Porras, SA Baldwin Pflügers Archiv 442, 614-621, 2001 | 61 | 2001 |
| Structure–Activity Studies of Cysteine‐Rich α‐Conotoxins that Inhibit High‐Voltage‐Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal … BB Carstens, G Berecki, JT Daniel, HS Lee, KAV Jackson, HS Tae, ... Angewandte Chemie International Edition 55 (15), 4692-4696, 2016 | 60 | 2016 |
Stuart M. BrierleyDirector, Visceral Pain Group & Hopwood Centre for Neurobiology. Co-leader Lifelong Health, SAHMRIVerified email at sahmri.com
