Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin AL Cogen, K Yamasaki, KM Sanchez, RA Dorschner, Y Lai, DT MacLeod, ... Journal of Investigative Dermatology 130 (1), 192-200, 2010 | 491 | 2010 |
Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections Y Lai, AL Cogen, KA Radek, HJ Park, DT MacLeod, A Leichtle, AF Ryan, ... Journal of Investigative Dermatology 130 (9), 2211-2221, 2010 | 482 | 2010 |
TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes K Yamasaki, K Kanada, DT Macleod, AW Borkowski, S Morizane, ... Journal of Investigative Dermatology 131 (3), 688-697, 2011 | 413 | 2011 |
Integration of a CD19 CAR into the TCR alpha chain locus streamlines production of allogeneic gene-edited CAR T cells DT MacLeod, J Antony, AJ Martin, RJ Moser, A Hekele, KJ Wetzel, ... Molecular Therapy 25 (4), 949-961, 2017 | 298 | 2017 |
Early antibody lineage diversification and independent limb maturation lead to broad HIV-1 neutralization targeting the Env high-mannose patch DT MacLeod, NM Choi, B Briney, F Garces, LS Ver, E Landais, B Murrell, ... Immunity 44 (5), 1215-1226, 2016 | 134 | 2016 |
Reinforcement of reproductive isolation between adjacent populations in the Park Grass Experiment J Silvertown, C Servaes, P Biss, D Macleod Heredity 95 (3), 198-205, 2005 | 118 | 2005 |
Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides Z Wang, Y Lai, JJ Bernard, DT MacLeod, AL Cogen, B Moss, A Di Nardo The Journal of Immunology 188 (1), 345-357, 2012 | 105 | 2012 |
Commensal bacteria lipoteichoic acid increases skin mast cell antimicrobial activity against vaccinia viruses Z Wang, DT MacLeod, A Di Nardo The Journal of Immunology 189 (4), 1551-1558, 2012 | 95 | 2012 |
Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene D Jantz, JJ Smith, MG Nicholson, DT MacLeod, V Bartsevich, J Antony US Patent 9,889,160, 2018 | 50 | 2018 |
HSV-1 exploits the innate immune scavenger receptor MARCO to enhance epithelial adsorption and infection DT MacLeod, T Nakatsuji, K Yamasaki, L Kobzik, RL Gallo Nature communications 4 (1), 1963, 2013 | 48 | 2013 |
Bcl-3 acts as an innate immune modulator by controlling antimicrobial responses in keratinocytes AS Büchau, DT MacLeod, S Morizane, PF Kotol, T Hata, RL Gallo Journal of investigative dermatology 129 (9), 2148-2155, 2009 | 45 | 2009 |
Vaccinia virus binds to the scavenger receptor MARCO on the surface of keratinocytes DT MacLeod, T Nakatsuji, Z Wang, A Di Nardo, RL Gallo Journal of Investigative Dermatology 135 (1), 142-150, 2015 | 39 | 2015 |
Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene D Jantz, JJ Smith, MG Nicholson, DT MacLeod, V Bartsevich, J Antony US Patent 9,889,161, 2018 | 23 | 2018 |
Kosakovsky Pond SL, Wilson IA, Burton DR, Poignard P. 2016. Early antibody lineage diversification and independent limb maturation lead to broad HIV-1 neutralization targeting … DT MacLeod, NM Choi, B Briney, F Garces, LS Ver, E Landais, B Murrell, ... Immunity 44 (5), 1215-1226, 0 | 22 | |
Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene D Jantz, JJ Smith, MG Nicholson, DT MacLeod, J Antony, V Bartsevich US Patent 9,993,502, 2018 | 14 | 2018 |
Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene D Jantz, JJ Smith, MG Nicholson, DT MacLeod, J Antony, V Bartsevich US Patent 10,093,900, 2018 | 13 | 2018 |
Engineered meganucleases with recognition sequences found in the human T cell receptor alpha constant region gene MG Nicholson, JJ Smith, D Jantz, V Bartsevich, DT MacLeod, J Antony US Patent 10,799,535, 2020 | 11 | 2020 |
Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene D Jantz, JJ Smith, MG Nicholson, DT MacLeod, J Antony, V Bartsevich US Patent 9,969,975, 2018 | 10 | 2018 |
Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene D Jantz, JJ Smith, MG Nicholson, DT MacLeod, J Antony, V Bartsevich US Patent 9,950,010, 2018 | 10 | 2018 |
Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene D Jantz, JJ Smith, MG Nicholson, DT MacLeod, J Antony, V Bartsevich US Patent 9,950,011, 2018 | 10 | 2018 |