Jessica Holien
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Oncogenic protein interfaces: small molecules, big challenges
TL Nero, CJ Morton, JK Holien, J Wielens, MW Parker
Nature Reviews Cancer 14 (4), 248-262, 2014
A Systematic and Functional Classification of Streptococcus pyogenes That Serves as a New Tool for Molecular Typing and Vaccine Development
M Sanderson-Smith, DMP De Oliveira, J Guglielmini, DJ McMillan, T Vu, ...
The Journal of infectious diseases 210 (8), 1325-1338, 2014
Zanamivir-resistant influenza viruses with a novel neuraminidase mutation
AC Hurt, JK Holien, M Parker, A Kelso, IG Barr
Journal of virology 83 (20), 10366-10373, 2009
Improvements, trends, and new ideas in molecular docking: 2012–2013 in review
E Yuriev, J Holien, PA Ramsland
Journal of Molecular Recognition 28 (10), 581-604, 2015
Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses
AC Hurt, JK Holien, MW Parker, IG Barr
Drugs 69, 2523-2531, 2009
In vitro generation of neuraminidase inhibitor resistance in A (H5N1) influenza viruses
AC Hurt, JK Holien, IG Barr
Antimicrobial agents and chemotherapy 53 (10), 4433-4440, 2009
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ...
Nature communications 6 (1), 6442, 2015
Mitochondrial fission–a drug target for cytoprotection or cytodestruction?
AA Rosdah, J K. Holien, LMD Delbridge, GJ Dusting, SY Lim
Pharmacology research & perspectives 4 (3), e00235, 2016
TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members
JL Bell, A Malyukova, JK Holien, J Koach, MW Parker, M Kavallaris, ...
PloS one 7 (5), e37470, 2012
Identification and development of specific inhibitors for insulin‐regulated aminopeptidase as a new class of cognitive enhancers
AL Albiston, S Diwakarla, RN Fernando, SJ Mountford, HR Yeatman, ...
British journal of pharmacology 164 (1), 37-47, 2011
Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor
N Etemadi, JK Holien, D Chau, G Dewson, JM Murphy, WS Alexander, ...
The FEBS journal 280 (21), 5283-5297, 2013
Crystal structure of human insulin‐regulated aminopeptidase with specificity for cyclic peptides
SJ Hermans, DB Ascher, NC Hancock, JK Holien, BJ Michell, SY Chai, ...
Protein Science 24 (2), 190-199, 2015
Direct involvement of the TEN domain at the active site of human telomerase
J Jurczyluk, AS Nouwens, JK Holien, TE Adams, GO Lovrecz, MW Parker, ...
Nucleic acids research 39 (5), 1774-1788, 2011
Synthesis, structure–activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase
SJ Mountford, AL Albiston, WN Charman, L Ng, JK Holien, MW Parker, ...
Journal of medicinal chemistry 57 (4), 1368-1377, 2014
Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity
SC Feil, S Lawrence, TD Mulhern, JK Holien, EM Hotze, S Farrand, ...
Structure 20 (2), 248-258, 2012
A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution
BP Paudel, AL Moye, H Abou Assi, R El-Khoury, SB Cohen, JK Holien, ...
Elife 9, e56428, 2020
Role of nicotinic acetylcholine receptor subunits in the mode of action of neonicotinoid, sulfoximine and spinosyn insecticides in Drosophila melanogaster
T Perry, W Chen, R Ghazali, YT Yang, D Christesen, F Martelli, C Lumb, ...
Insect Biochemistry and Molecular Biology 131, 103547, 2021
New perspectives on the role of Drp1 isoforms in regulating mitochondrial pathophysiology
AA Rosdah, WJ Smiles, JS Oakhill, JW Scott, CG Langendorf, ...
Pharmacology & Therapeutics 213, 107594, 2020
Mechanistic scrutiny identifies a kinetic role for cytochrome b5 regulation of human cytochrome P450c17 (CYP17A1, P450 17A1)
AN Simonov, JK Holien, JCI Yeung, AD Nguyen, CJ Corbin, J Zheng, ...
PLoS One 10 (11), e0141252, 2015
Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission
SB Kalkhoran, J Kriston-Vizi, S Hernandez-Resendiz, GE Crespo-Avilan, ...
Cardiovascular Research 118 (1), 282-294, 2022
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