Nicole La Gruta
Nicole La Gruta
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A question of self‐preservation: immunopathology in influenza virus infection
NL La Gruta, K Kedzierska, J Stambas, PC Doherty
Immunology and cell biology 85 (2), 85-92, 2007
Quantifiable predictive features define epitope-specific T cell receptor repertoires
P Dash, AJ Fiore-Gartland, T Hertz, GC Wang, S Sharma, A Souquette, ...
Nature 547 (7661), 89-93, 2017
A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis
SW Scally, J Petersen, SC Law, NL Dudek, HJ Nel, KL Loh, ...
The Journal of experimental medicine 210 (12), 2569-2582, 2013
Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: correlation of cytokine profile and TCR avidity
NL La Gruta, SJ Turner, PC Doherty
The Journal of Immunology 172 (9), 5553-5560, 2004
A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies
NL La Gruta, K Kedzierska, K Pang, R Webby, M Davenport, W Chen, ...
Proceedings of the National Academy of Sciences 103 (4), 994-999, 2006
Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion
NL La Gruta, WT Rothwell, T Cukalac, NG Swan, SA Valkenburg, ...
The Journal of clinical investigation 120 (6), 1885-1894, 2010
Lack of prominent peptide–major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
SJ Turner, K Kedzierska, H Komodromou, NL La Gruta, MA Dunstone, ...
Nature immunology 6 (4), 382-389, 2005
T cell mediated immunity to influenza: mechanisms of viral control
NL La Gruta, SJ Turner
Trends in immunology 35 (8), 396-402, 2014
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells
JD Ooi, J Petersen, YH Tan, M Huynh, ZJ Willett, SH Ramarathinam, ...
Nature 545 (7653), 243-247, 2017
T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease
J Petersen, V Montserrat, JR Mujico, KL Loh, DX Beringer, M Van Lummel, ...
Nature structural & molecular biology 21 (5), 480-488, 2014
The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues
PY Arnold, NL La Gruta, T Miller, KM Vignali, PS Adams, DL Woodland, ...
The Journal of Immunology 169 (2), 739-749, 2002
Sizing up the key determinants of the CD8+ T cell response
DC Tscharke, NP Croft, PC Doherty, NL La Gruta
Nature Reviews Immunology 15 (11), 705-716, 2015
Age-related decline in primary CD8+ T cell responses is associated with the development of senescence in virtual memory CD8+ T cells
KM Quinn, A Fox, KL Harland, BE Russ, J Li, THO Nguyen, L Loh, ...
Cell Reports 23 (12), 3512-3524, 2018
Understanding the drivers of MHC restriction of T cell receptors
NL La Gruta, S Gras, SR Daley, PG Thomas, J Rossjohn
Nature Reviews Immunology 18 (7), 467-478, 2018
A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo
ZZ Lieu, JG Lock, LA Hammond, NL La Gruta, JL Stow, PA Gleeson
Proceedings of the National Academy of Sciences 105 (9), 3351-3356, 2008
Peripheral T cell expansion in lymphopenic mice results in a restricted T cell repertoire
NLL Gruta, IR Driel, PA Gleeson
European journal of immunology 30 (12), 3380-3386, 2000
The structural basis for autonomous dimerization of the pre-T-cell antigen receptor
SS Pang, R Berry, Z Chen, L Kjer-Nielsen, MA Perugini, GF King, C Wang, ...
Nature 467 (7317), 844-848, 2010
Functional implications of T cell receptor diversity
SJ Turner, NL La Gruta, K Kedzierska, PG Thomas, PC Doherty
Current opinion in immunology 21 (3), 286-290, 2009
Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens
LJ Young, NS Wilson, P Schnorrer, A Mount, RJ Lundie, NL La Gruta, ...
Proceedings of the National Academy of Sciences 104 (45), 17753-17758, 2007
Clonally diverse CD38+ HLA-DR+ CD8+ T cells persist during fatal H7N9 disease
Z Wang, L Zhu, THO Nguyen, Y Wan, S Sant, SM Quiñones-Parra, ...
Nature communications 9 (1), 1-12, 2018
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