Seth Lucian Masters

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Daniel KastnerScientific Director, National Human Genome Research Institute, NIHVerified email at mail.nih.gov
Ben A CrokerUC San DiegoVerified email at ucsd.edu
Professor Kate SchroderClarivate Highly Cited Researcher; Lab Head, Institute for Molecular Bioscience, University of QLDVerified email at imb.uq.edu.au
Eicke LatzInstitute of Innate Immunity, University of Bonn and University of Massachusetts Medical SchoolVerified email at umassmed.edu
Gabriel NuñezPaul de Kruif Professor of Pathology, University of Michigan Medical SchoolVerified email at umich.edu
Ivona AksentijevichNational Human Genome Research Institute, BethesdaVerified email at mail.nih.gov
Kingston MillsTrinity College DublinVerified email at tcd.ie
Kate E LawlorGroup Head, Cell Death and Inflammatory Signalling, Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research and Adjunct Research Fellow, Department of Molecular and Translational Science, Monash UniversityVerified email at hudson.org.au
Andrew MurphyBaker Heart, Baker IDI, Columbia UniversityVerified email at bakeridi.edu.au
Benjamin KileUniversity of AdelaideVerified email at adelaide.edu.au
Lisa Mielke, PhDLaboratory Head, Olivia Newton-John Cancer Research InstituteVerified email at onjcri.org.au
Sandra NicholsonThe Walter and Eliza Hall InstituteVerified email at wehi.edu.au
Chien-Hsiung YuThe Walter and Eliza Hall Institute of Medical ResearchVerified email at wehi.edu.au
Fiona MoghaddasThe Walter and Eliza Hall Institute of Medical Research, The Royal Melbourne HospitalVerified email at wehi.edu.au
Richard FerreroHudson Institute of Medical Research & Monash University (Professor)Verified email at hudson.org.au
Axel KalliesUniversity of MelbourneVerified email at unimelb.edu.au
Ed C LavelleSchool of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College DublinVerified email at tcd.ie
Elizabeth HartlandHudson Institute of Medical ResearchVerified email at hudson.org.au
Franklin ZhongNTU, SingaporeVerified email at ntu.edu.sg
Prof. Dr. Bruno REVERSADEGIS & IMCB, A*STAR, SingaporeVerified email at reversade.com

Seth Lucian Masters

The Walter and Eliza Hall Institute

Verified email at wehi.edu.au - Homepage

Inflammasome Autoinflammatory Disease Inflammation


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Succinate is an inflammatory signal that induces IL-1β through HIF-1α GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ... Nature 496 (7444), 238-242, 2013	2551	2013
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases RC Coll, AAB Robertson, JJ Chae, SC Higgins, R Muñoz-Planillo, ... Nature medicine 21 (3), 248-255, 2015	1724	2015
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ... Nature immunology 11 (10), 897-904, 2010	1256	2010
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus EF Remmers, RM Plenge, AT Lee, RR Graham, G Hom, TW Behrens, ... New England Journal of Medicine 357 (10), 977-986, 2007	1218	2007
Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease SL Masters, A Simon, I Aksentijevich, DL Kastner Annual review of immunology 27, 621, 2009	1189	2009
An autoinflammatory disease with deficiency of the interleukin-1–receptor antagonist I Aksentijevich, SL Masters, PJ Ferguson, P Dancey, J Frenkel, ... New England Journal of Medicine 360 (23), 2426-2437, 2009	925	2009
The B30. 2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β production JJ Chae, G Wood, SL Masters, K Richard, G Park, BJ Smith, DL Kastner Proceedings of the National Academy of Sciences 103 (26), 9982-9987, 2006	640	2006
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice AR Mridha, A Wree, AAB Robertson, MM Yeh, CD Johnson, ... Journal of hepatology 66 (5), 1037-1046, 2017	574	2017
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ... Cell 157 (5), 1175-1188, 2014	495	2014
The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells A Vasanthakumar, K Moro, A Xin, Y Liao, R Gloury, S Kawamoto, ... Nature immunology 16 (3), 276-285, 2015	463	2015
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL KE Lawlor, N Khan, A Mildenhall, M Gerlic, BA Croker, AA D’Cruz, C Hall, ... Nature communications 6 (1), 1-19, 2015	459	2015
Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production M Haneklaus, M Gerlic, M Kurowska-Stolarska, AA Rainey, D Pich, ... The Journal of Immunology 189 (8), 3795-3799, 2012	408	2012
Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity PR Nagareddy, M Kraakman, SL Masters, RA Stirzaker, DJ Gorman, ... Cell metabolism 19 (5), 821-835, 2014	386	2014
miR‐223: infection, inflammation and cancer M Haneklaus, M Gerlic, LAJ O'Neill, SL Masters Journal of internal medicine 274 (3), 215-226, 2013	360	2013
Familial mediterranean fever with a single MEFV mutation: Where is the second hit? MG Booty, JJ Chae, SL Masters, EF Remmers, B Barham, JM Le, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009	284	2009
NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells SL Masters, M Gerlic, D Metcalf, S Preston, M Pellegrini, JA O’Donnell, ... Immunity 37 (6), 1009-1023, 2012	276	2012
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation FL Zhong, O Mamaï, L Sborgi, L Boussofara, R Hopkins, K Robinson, ... Cell 167 (1), 187-202. e17, 2016	265	2016
Evidence that TLR4 is not a receptor for saturated fatty acids but mediates lipid-induced inflammation by reprogramming macrophage metabolism GI Lancaster, KG Langley, NA Berglund, HL Kammoun, S Reibe, ... Cell metabolism 27 (5), 1096-1110. e5, 2018	263	2018
Homeostasis-altering molecular processes as mechanisms of inflammasome activation A Liston, SL Masters Nature Reviews Immunology 17 (3), 208-214, 2017	263	2017
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G Núñez, ... Proceedings of the National Academy of Sciences 114 (6), E961-E969, 2017	258	2017

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