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Richard W Birkinshaw
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T-cell activation by transitory neo-antigens derived from distinct microbial pathways
AJ Corbett, SBG Eckle, RW Birkinshaw, L Liu, O Patel, J Mahony, Z Chen, ...
Nature 509 (7500), 361-365, 2014
7852014
Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells
R Reantragoon, AJ Corbett, IG Sakala, NA Gherardin, JB Furness, Z Chen, ...
Journal of Experimental Medicine 210 (11), 2305-2320, 2013
5802013
Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia
P Blombery, MA Anderson, J Gong, R Thijssen, RW Birkinshaw, ...
Cancer discovery 9 (3), 342-353, 2019
3762019
Recognition of vitamin B metabolites by mucosal-associated invariant T cells
O Patel, L Kjer-Nielsen, J Le Nours, SBG Eckle, R Birkinshaw, T Beddoe, ...
Nature communications 4 (1), 2142, 2013
2922013
A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells
SBG Eckle, RW Birkinshaw, L Kostenko, AJ Corbett, HEG McWilliam, ...
Journal of Experimental Medicine 211 (8), 1585-1600, 2014
2792014
The BCL-2 family of proteins and mitochondrial outer membrane permeabilisation
RW Birkinshaw, PE Czabotar
Seminars in cell & developmental biology 72, 152-162, 2017
2522017
Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells
AN Keller, SBG Eckle, W Xu, L Liu, VA Hughes, JYW Mak, BS Meehan, ...
Nature immunology 18 (4), 402-411, 2017
2172017
Diversity of T cells restricted by the MHC class I-related molecule MR1 facilitates differential antigen recognition
NA Gherardin, AN Keller, RE Woolley, J Le Nours, DS Ritchie, PJ Neeson, ...
Immunity 44 (1), 32-45, 2016
1962016
CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens
A De Jong, TY Cheng, S Huang, S Gras, RW Birkinshaw, AG Kasmar, ...
Nature immunology 15 (2), 177-185, 2014
1682014
Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations
RW Birkinshaw, J Gong, CS Luo, D Lio, CA White, MA Anderson, ...
Nature communications 10 (1), 2385, 2019
1622019
Multiple BCL2 mutations cooccurring with Gly101Val emerge in chronic lymphocytic leukemia progression on venetoclax
P Blombery, ER Thompson, T Nguyen, RW Birkinshaw, J Gong, X Chen, ...
Blood, The Journal of the American Society of Hematology 135 (10), 773-777, 2020
1352020
αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands
RW Birkinshaw, DG Pellicci, TY Cheng, AN Keller, M Sandoval-Romero, ...
Nature immunology 16 (3), 258-266, 2015
1332015
Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex
W Wong, R Huang, S Menant, C Hong, JJ Sandow, RW Birkinshaw, ...
Nature 565 (7737), 118-121, 2019
832019
MAITs, MR1 and vitamin B metabolites
RW Birkinshaw, L Kjer-Nielsen, SBG Eckle, J McCluskey, J Rossjohn
Current opinion in immunology 26, 7-13, 2014
832014
Cutting edge: CD1a tetramers and dextramers identify human lipopeptide–specific T cells ex vivo
AG Kasmar, I Van Rhijn, KG Magalhaes, DC Young, TY Cheng, ...
The Journal of Immunology 191 (9), 4499-4503, 2013
812013
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
EJ Petrie, RW Birkinshaw, A Koide, E Denbaum, JM Hildebrand, ...
Proceedings of the National Academy of Sciences 117 (15), 8468-8475, 2020
622020
Conversion of Bim-BH3 from activator to inhibitor of Bak through structure-based design
JM Brouwer, P Lan, AD Cowan, JP Bernardini, RW Birkinshaw, ...
Molecular cell 68 (4), 659-672. e9, 2017
582017
MR1 presentation of vitamin B-based metabolite ligands
HEG McWilliam, RW Birkinshaw, JA Villadangos, J McCluskey, ...
Current opinion in immunology 34, 28-34, 2015
542015
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues
KA Davies, C Fitzgibbon, SN Young, SE Garnish, W Yeung, D Coursier, ...
Nature Communications 11 (1), 3060, 2020
482020
Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes
J Healer, W Wong, JK Thompson, W He, RW Birkinshaw, K Miura, ...
Cellular microbiology 21 (7), e13030, 2019
432019
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