| Inhibition of the mitochondrial protease ClpP as a therapeutic strategy for human acute myeloid leukemia A Cole, Z Wang, E Coyaud, V Voisin, M Gronda, Y Jitkova, R Mattson, ... Cancer cell 27 (6), 864-876, 2015 | 328 | 2015 |
| Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and mechanisms of temozolomide sensitivity in glioblastoma stem cells G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ... Cell reports 27 (3), 971-986. e9, 2019 | 194 | 2019 |
| PRMT5 inhibition disrupts splicing and stemness in glioblastoma P Sachamitr, JC Ho, FE Ciamponi, W Ba-Alawi, FJ Coutinho, ... Nature communications 12 (1), 979, 2021 | 87 | 2021 |
| PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1 A Gont, JEL Hanson, SJ Lavictoire, DAE Parolin, M Daneshmand, ... Oncotarget 4 (8), 1266, 2013 | 43 | 2013 |
| Repression of cancer cell senescence by PKCι JA Paget, IJ Restall, M Daneshmand, JA Mersereau, MA Simard, ... Oncogene 31 (31), 3584-3596, 2012 | 41 | 2012 |
| Induction of premature senescence by hsp90 inhibition in small cell lung cancer IJ Restall, IAJ Lorimer PLoS One 5 (6), e11076, 2010 | 31 | 2010 |
| Brain tumor stem cell dependence on glutaminase reveals a metabolic vulnerability through the amino acid deprivation response pathway IJ Restall, O Cseh, LM Richards, TJ Pugh, HA Luchman, S Weiss Cancer Research 80 (24), 5478-5490, 2020 | 15 | 2020 |
| Isolation and culture of glioblastoma brain tumor stem cells C Chesnelong, I Restall, S Weiss Brain Tumor Stem Cells: Methods and Protocols, 11-21, 2019 | 14 | 2019 |
| PKCι depletion initiates mitotic slippage-induced senescence in glioblastoma IJ Restall, DAE Parolin, M Daneshmand, JEL Hanson, MA Simard, ... Cell Cycle 14 (18), 2938-2948, 2015 | 12 | 2015 |
| Live-Cell imaging assays to study glioblastoma brain tumor stem cell migration and invasion I Restall, DA Bozek, C Chesnelong, S Weiss, HA Luchman JoVE (Journal of Visualized Experiments), e58152, 2018 | 11 | 2018 |
| Chemical genomics reveals targetable programs of human cancers rooted in pluripotency L Orlando, YD Benoit, JC Reid, M Nakanishi, AL Boyd, ... Cell chemical biology 30 (7), 780-794. e8, 2023 | 4 | 2023 |
| The functional genomic circuitry of human glioblastoma stem cells G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ... BioRxiv, 358432, 2018 | 3 | 2018 |
| STAT3 is a central regulator of proliferation, invasion and metabolism in GBM tumor initiating cells I Restall, HA Luchman, S Weiss Cancer Research 76 (14_Supplement), 2521-2521, 2016 | 1 | 2016 |
| Repression of cancer cell senescence by PKCι IJ Restall, JA Paget, M Daneshmand, MS Amin, S Islam, IAJ Lorimer Cancer Research 71 (8_Supplement), 1224-1224, 2011 | 1 | 2011 |
| STEM-41. A SUBSET OF GBM BRAIN TUMOR STEM CELL LINES ARE UNIQUELY DEPENDENT ON GLUTAMINE METABOLISM FOR AMINO ACID SYNTHESIS I Restall, HA Luchman, S Weiss Neuro-Oncology 19 (Suppl 6), vi234, 2017 | | 2017 |
| STAT3 IS A CENTRAL REGULATOR OF PROLIFERATION, INVASION, MIGRATION AND METABOLISM IN GBM TUMOR INITIATING CELLS I Restall, HA Luchman, S Weiss NEURO-ONCOLOGY 18, 38-39, 2016 | | 2016 |
| Inactivation of the tumor suppressor Lgl via PTEN loss promotes the invasiveness of glioblastoma multiforme. A Gont, J Hanson, M Soucie, A Kassam, V DaSilva, J Woulfe, G Nicholas, ... Cancer Research 73 (8_Supplement), 1968-1968, 2013 | | 2013 |
| Inducing cellular senescence in cancer IJ Restall Université d'Ottawa/University of Ottawa, 2013 | | 2013 |
