| Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis DM Hutt, D Herman, APC Rodrigues, S Noel, JM Pilewski, J Matteson, ... Nature chemical biology 6 (1), 25-33, 2010 | 283 | 2010 |
| Cystic fibrosis: insight into CFTR pathophysiology and pharmacotherapy B Lubamba, B Dhooghe, S Noel, T Leal Clinical biochemistry 45 (15), 1132-1144, 2012 | 211 | 2012 |
| Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the α-glucosidase inhibitor miglustat C Norez, S Noel, M Wilke, M Bijvelds, H Jorna, P Melin, H DeJonge, ... FEBS letters 580 (8), 2081-2086, 2006 | 202 | 2006 |
| In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities BZ Schmidt, M Lehmann, S Gutbier, E Nembo, S Noel, L Smirnova, ... Archives of toxicology 91 (1), 1-33, 2017 | 138 | 2017 |
| Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis J Simonin, E Bille, G Crambert, S Noel, E Dreano, A Edwards, A Hatton, ... Scientific reports 9 (1), 1-11, 2019 | 83 | 2019 |
| Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectives BZ Schmidt, JB Haaf, T Leal, S Noel Clinical pharmacology: advances and applications 8, 127, 2016 | 78 | 2016 |
| A cystic fibrosis respiratory epithelial cell chronically treated by miglustat acquires a non-cystic fibrosis-like phenotype C Norez, F Antigny, S Noel, C Vandebrouck, F Becq American journal of respiratory cell and molecular biology 41 (2), 217, 2010 | 77 | 2010 |
| Lung inflammation in cystic fibrosis: Pathogenesis and novel therapies B Dhooghe, S Noël, F Huaux, T Leal Clinical biochemistry 47 (7), 539-546, 2014 | 72 | 2014 |
| Parallel improvement of sodium and chloride transport defects by miglustat (n-butyldeoxynojyrimicin) in cystic fibrosis epithelial cells S Noel, M Wilke, AGM Bot, HR De Jonge, F Becq Journal of Pharmacology and Experimental Therapeutics 325 (3), 1016-1023, 2008 | 55 | 2008 |
| Discovery of pyrrolo [2, 3-b] pyrazines derivatives as submicromolar affinity activators of wild type, G551D, and F508del cystic fibrosis transmembrane conductance regulator … S Noel, C Faveau, C Norez, C Rogier, Y Mettey, F Becq Journal of Pharmacology and Experimental Therapeutics 319 (1), 349-359, 2006 | 49 | 2006 |
| Dysregulated proinflammatory and fibrogenic phenotype of fibroblasts in cystic fibrosis F Huaux, S Noel, B Dhooghe, N Panin, SL Re, D Lison, P Wallemacq, ... PloS one 8 (5), e64341, 2013 | 40 | 2013 |
| PDE5 Inhibitors as Potential Tools in the Treatment of Cystic Fibrosis S Noel, B Dhooghe, T Leal Frontiers in Pharmacology 3, 167, 2012 | 39 | 2012 |
| Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del‐CFTR by a CDK‐independent mechanism C Norez, C Vandebrouck, J Bertrand, S Noel, E Durieu, N Oumata, ... British journal of pharmacology 171 (21), 4831-4849, 2014 | 36 | 2014 |
| Strategies in early clinical development for the treatment of basic defects of cystic fibrosis B Dhooghe, JB Haaf, S Noel, T Leal Expert opinion on investigational drugs 25 (4), 423-436, 2016 | 30 | 2016 |
| Correction of Chloride Transport and Mislocalization of CFTR Protein by Vardenafil in the Gastrointestinal Tract of Cystic Fibrosis Mice B Dhooghe, S Noël, C Bouzin, G Behets-Wydemans, T Leal PloS one 8 (10), e77314, 2013 | 25 | 2013 |
| Lung immunoglobulin A immunity dysregulation in cystic fibrosis AM Collin, M Lecocq, S Noel, B Detry, FM Carlier, FA Nana, C Bouzin, ... EBioMedicine 60, 102974, 2020 | 24 | 2020 |
| Evaluation of eluforsen, a novel RNA oligonucleotide for restoration of CFTR function in in vitro and murine models of p.Phe508del cystic fibrosis W Beumer, J Swildens, T Leal, S Noel, H Anthonijsz, G van der Horst, ... PloS one 14 (6), e0219182, 2019 | 22 | 2019 |
| Discovery of α-aminoazaheterocycle-methylglyoxal adducts as a new class of high-affinity inhibitors of cystic fibrosis transmembrane conductance regulator chloride channels C Routaboul, C Norez, P Melin, MC Molina, B Boucherle, F Bossard, ... Journal of Pharmacology and Experimental Therapeutics 322 (3), 1023-1035, 2007 | 22 | 2007 |
| Discovery of α-aminoazaheterocycle-methylglyoxal adducts as a new class of high-affinity inhibitors of cystic fibrosis transmembrane conductance regulator chloride channels C Routaboul, C Norez, P Melin, MC Molina, B Boucherle, F Bossard, ... Journal of Pharmacology and Experimental Therapeutics 322 (3), 1023-1035, 2007 | 22 | 2007 |
| Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice B Dhooghe, C Bouckaert, A Capron, P Wallemacq, T Leal, S Noel Biology open 4 (7), 929-936, 2015 | 19 | 2015 |
barbara dhoogheUniversité Catholique de LouvainVerified email at uclouvain.be
