| K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates J Straimer, NF Gnädig, B Witkowski, C Amaratunga, V Duru, ... Science 347 (6220), 428-431, 2015 | 767 | 2015 |
| Artemisinin action and resistance in Plasmodium falciparum L Tilley, J Straimer, NF Gnädig, SA Ralph, DA Fidock Trends in parasitology 32 (9), 682-696, 2016 | 379 | 2016 |
| Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance C Dogovski, SC Xie, G Burgio, J Bridgford, S Mok, JM McCaw, ... PLoS biology 13 (4), e1002132, 2015 | 341 | 2015 |
| Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies MI Veiga, SK Dhingra, PP Henrich, J Straimer, N Gnädig, AC Uhlemann, ... Nature communications 7 (1), 11553, 2016 | 264 | 2016 |
| Dihydroartemisinin–piperaquine failure in Cambodia DL Saunders, P Vanachayangkul, C Lon New England Journal of Medicine 371 (5), 484-485, 2014 | 231 | 2014 |
| Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ... Science 359 (6372), 191-199, 2018 | 217 | 2018 |
| Coxsackievirus B3 mutator strains are attenuated in vivo NF Gnädig, S Beaucourt, G Campagnola, AV Bordería, M Sanz-Ramos, ... Proceedings of the National Academy of Sciences 109 (34), E2294-E2303, 2012 | 154 | 2012 |
| Group selection and contribution of minority variants during virus adaptation determines virus fitness and phenotype AV Bordería, O Isakov, G Moratorio, R Henningsson, S Agüera-González, ... PLoS pathogens 11 (5), e1004838, 2015 | 125 | 2015 |
| Plasmodium falciparum K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness In Vitro J Straimer, NF Gnädig, BH Stokes, M Ehrenberger, AA Crane, DA Fidock MBio 8 (2), 10.1128/mbio. 00172-17, 2017 | 115 | 2017 |
| A broad analysis of resistance development in the malaria parasite VC Corey, AK Lukens, ES Istvan, MCS Lee, V Franco, P Magistrado, ... Nature communications 7 (1), 11901, 2016 | 115 | 2016 |
| Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness BH Stokes, SK Dhingra, K Rubiano, S Mok, J Straimer, NF Gnädig, I Deni, ... Elife 10, e66277, 2021 | 103 | 2021 |
| Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival S Mok, BH Stokes, NF Gnädig, LS Ross, T Yeo, C Amaratunga, E Allman, ... Nature communications 12 (1), 530, 2021 | 95 | 2021 |
| Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds LI Levi, NF Gnädig, S Beaucourt, MJ McPherson, B Baron, JJ Arnold, ... PLoS pathogens 6 (10), e1001163, 2010 | 93 | 2010 |
| Transcytosis of HTLV-1 across a tight human epithelial barrier and infection of subepithelial dendritic cells S Martin-Latil, NF Gnädig, A Mallet, M Desdouits, F Guivel-Benhassine, ... Blood, The Journal of the American Society of Hematology 120 (3), 572-580, 2012 | 79 | 2012 |
| Mutational robustness of an RNA virus influences sensitivity to lethal mutagenesis JD Graci, NF Gnädig, JE Galarraga, C Castro, M Vignuzzi, CE Cameron Journal of virology 86 (5), 2869-2873, 2012 | 76 | 2012 |
| Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria DK Raj, A Das Mohapatra, A Jnawali, J Zuromski, A Jha, G Cham-Kpu, ... Nature 582 (7810), 104-108, 2020 | 72 | 2020 |
| A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance PM O’Neill, RK Amewu, SA Charman, S Sabbani, NF Gnädig, J Straimer, ... Nature Communications 8 (1), 15159, 2017 | 67 | 2017 |
| Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13 NF Gnädig, BH Stokes, RL Edwards, GF Kalantarov, KC Heimsch, ... PLoS pathogens 16 (4), e1008482, 2020 | 66 | 2020 |
| The antimalarial natural product salinipostin A identifies essential α/β serine hydrolases involved in lipid metabolism in P. falciparum parasites E Yoo, CJ Schulze, BH Stokes, O Onguka, T Yeo, S Mok, NF Gnädig, ... Cell chemical biology 27 (2), 143-157. e5, 2020 | 54 | 2020 |
| Isolation of fidelity variants of RNA viruses and characterization of virus mutation frequency S Beaucourt, AV Bordería, LL Coffey, NF Gnädig, M Sanz-Ramos, ... JoVE (Journal of Visualized Experiments), e2953, 2011 | 49 | 2011 |
