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Eugene Valkov
Eugene Valkov
Stadtman Investigator, NCI/NIH
Verified email at nih.gov - Homepage
Title
Cited by
Cited by
Year
Retroviral intasome assembly and inhibition of DNA strand transfer
S Hare, SS Gupta, E Valkov, A Engelman, P Cherepanov
Nature 464 (7286), 232-236, 2010
7902010
A molecular mechanism for bacterial susceptibility to zinc
CA McDevitt, AD Ogunniyi, E Valkov, MC Lawrence, B Kobe, AG McEwan, ...
PLoS pathogens 7 (11), e1002357, 2011
4562011
Structural and functional analysis of a plant resistance protein TIR domain reveals interfaces for self-association, signaling, and autoregulation
M Bernoux, T Ve, S Williams, C Warren, D Hatters, E Valkov, X Zhang, ...
Cell host & microbe 9 (3), 200-211, 2011
3872011
Improved molecular replacement by density-and energy-guided protein structure optimization
F DiMaio, TC Terwilliger, RJ Read, A Wlodawer, G Oberdorfer, U Wagner, ...
Nature 473 (7348), 540-543, 2011
2642011
A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75
S Hare, MC Shun, SS Gupta, E Valkov, A Engelman, P Cherepanov
PLoS pathogens 5 (1), e1000259, 2009
1802009
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
E Valkov, A Stamp, F DiMaio, D Baker, B Verstak, P Roversi, S Kellie, ...
Proceedings of the National Academy of Sciences 108 (36), 14879-14884, 2011
1542011
Functional and structural characterization of the integrase from the prototype foamy virus
E Valkov, SS Gupta, S Hare, A Helander, P Roversi, M McClure, ...
Nucleic acids research 37 (1), 243-255, 2009
1512009
The structures of eIF4E-eIF4G complexes reveal an extended interface to regulate translation initiation
S Grüner, D Peter, R Weber, L Wohlbold, MY Chung, O Weichenrieder, ...
Molecular cell 64 (3), 467-479, 2016
1232016
Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery.
E Valkov, T Sharpe, M Marsh, S Greive, M Hyvönen
Topics in current chemistry, 2011
1222011
Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation
T Raisch, CT Chang, Y Levdansky, S Muthukumar, S Raunser, E Valkov
Nature Communications 10 (1), 3173, 2019
812019
Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export
D Jani, E Valkov, M Stewart
Nucleic acids research 42 (10), 6686-6697, 2014
812014
GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression
D Peter, R Weber, F Sandmeir, L Wohlbold, S Helms, P Bawankar, ...
Genes & Development 31 (11), 1147-1161, 2017
802017
Structural basis for P an3 binding to P an2 and its function in mRNA recruitment and deadenylation
J Wolf, E Valkov, MD Allen, B Meineke, Y Gordiyenko, SH McLaughlin, ...
The EMBO journal 33 (14), 1514-1526, 2014
762014
Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB
M Alaidarous, T Ve, LW Casey, E Valkov, DJ Ericsson, MO Ullah, ...
Journal of Biological Chemistry 289 (2), 654-668, 2014
742014
VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins
JD Swarbrick, DJ Shaw, S Chhabra, R Ghai, E Valkov, SJ Norwood, ...
PLoS One 6 (5), e20420, 2011
702011
De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans
CA Morrow, E Valkov, A Stamp, EWL Chow, IR Lee, A Wronski, ...
Public Library of Science 8 (10), e1002957, 2012
692012
Distinct modes of recruitment of the CCR4–NOT complex by Drosophila and vertebrate Nanos
T Raisch, D Bhandari, K Sabath, S Helms, E Valkov, O Weichenrieder, ...
The EMBO journal 35 (9), 974-990, 2016
652016
Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation
E Valkov, S Muthukumar, CT Chang, S Jonas, O Weichenrieder, ...
Nature structural & molecular biology 23 (6), 574-579, 2016
582016
The principal mRNA nuclear export factor NXF1: NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA
S Aibara, J Katahira, E Valkov, M Stewart
Nucleic acids research 43 (3), 1883-1893, 2015
542015
4EHP and GIGYF1/2 mediate translation-coupled messenger RNA decay
R Weber, MY Chung, C Keskeny, U Zinnall, M Landthaler, E Valkov, ...
Cell reports 33 (2), 2020
472020
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