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Sarah Alexandrou
Sarah Alexandrou
Verified email at garvan.org.au
Title
Cited by
Cited by
Year
The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer
TE Hickey, LA Selth, KM Chia, G Laven-Law, HH Milioli, D Roden, ...
Nature medicine 27 (2), 310-320, 2021
1512021
Overcoming CDK4/6 inhibitor resistance in ER-positive breast cancer
N Portman, S Alexandrou, E Carson, S Wang, E Lim, CE Caldon
Endocrine-related cancer 26 (1), R15-R30, 2019
1322019
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer
N Portman, HH Milioli, S Alexandrou, R Coulson, A Yong, KJ Fernandez, ...
Breast Cancer Research 22, 1-17, 2020
422020
The proliferative and apoptotic landscape of basal-like breast cancer
S Alexandrou, SM George, CJ Ormandy, E Lim, SR Oakes, CE Caldon
International journal of molecular sciences 20 (3), 667, 2019
272019
Cyclin E1 and cyclin E2 in ER+ breast cancer: prospects as biomarkers and therapeutic targets
HH Milioli, S Alexandrou, E Lim, CE Caldon
Endocrine-related cancer 27 (5), R93-R112, 2020
232020
Cyclin E2 promotes whole genome doubling in breast cancer
C Lee, KJ Fernandez, S Alexandrou, CM Sergio, N Deng, S Rogers, ...
Cancers 12 (8), 2268, 2020
202020
Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition
D Aziz, N Portman, KJ Fernandez, C Lee, S Alexandrou, A Llop-Guevara, ...
NPJ Breast Cancer 7 (1), 111, 2021
82021
miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma
H Holliday, J Yang, E Dodson, I Nikolic, A Kamili, M Wheatley, N Deng, ...
Molecular Therapy 30 (3), 1119-1134, 2022
52022
Abstract PD2-02: Combination CDK4/6 inhibition and AR agonism suppresses the growth of CDK4/6 inhibitor resistant breast cancers
A Freelander, G Laven-Law, L Eshraghi, KM Chia, M Pickering, A Yong, ...
Cancer Research 82 (4_Supplement), PD2-02-PD2-02, 2022
32022
Cyclin E1 protein is stabilized in BRCA1 mutated breast cancers leading to synergy between CDK2 and PARP inhibitors
D Aziz, N Portman, KJ Fernandez, C Lee, S Alexandrou, A Llop-Guevara, ...
bioRxiv, 2020.01. 29.911883, 2020
32020
The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer
J Achinger-Kawecka, C Stirzaker, N Portman, E Campbell, KM Chia, Q Du, ...
Nature Structural & Molecular Biology, 1-15, 2024
12024
Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer
J Achinger-Kawecka, C Stirzaker, N Portman, E Campbell, K Chia, Q Du, ...
12021
Abstract P4-04-12: Therapeutic targeting of CDK4/6 inhibitor resistant breast cancer
E Lim, N Portman, S Alexandrou, S Haupt, Y Haupt, E Caldon
Cancer Research 78 (4_Supplement), P4-04-12-P4-04-12, 2018
12018
Abstract P4-08-16: Selective Androgen Receptor Modulators in combination with CDK4/6 inhibitors demonstrate anti-cancer activity in preclinical treatment resistant ER+ AR+ …
A Freelander, G laven-Law, L Eshraghi, N Geetha, P Somerville, ...
Cancer Research 83 (5_Supplement), P4-08-16-P4-08-16, 2023
2023
Abstract PS18-17: Mdm2 inhibition synergises with endocrine therapy or cdk4/6 inhibition for the treatment of estrogen receptor-positive breast cancer
N Portman, H Milioli, S Alexandrou, R Coulson, A Yong, K Fernandez, ...
Cancer Research 81 (4_Supplement), PS18-17-PS18-17, 2021
2021
Mdm2 inhibition synergises with endocrine therapy or cdk4/6 inhibition for the treatment of estrogen receptor-positive breast cancer
N Portman, H Milioli, S Alexandrou, R Coulson, A Yong, K Fernandez, ...
CANCER RESEARCH 81 (4), 2021
2021
Elucidating the mechanisms of resistance to CDK4/6 inhibitors and endocrine therapy in ER+ breast cancer
S Alexandrou
UNSW Sydney, 2021
2021
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer
E Lim, HH Milioli, S Alexandrou, R Coulson, A Yong, KJ Fernandez, ...
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 16, 110-110, 2020
2020
Mechanisms underlying uncontrolled genome doubling in breast cancer
CS Lee, S Rogers, K Fernandez, S Alexandrou, N Deng, CM Sergio, ...
Oncology Abstracts, 2019
2019
Supplementary Materials: Cyclin E2 Promotes Whole Genome Doubling in Breast Cancer
C Lee, K Fernandez, S Alexandrou, CM Sergio, N Deng, S Rogers, ...
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