Single-channel behavior of heteromeric α1β glycine receptors: an attempt to detect a conformational change before the channel opens V Burzomato, M Beato, PJ Groot-Kormelink, D Colquhoun, LG Sivilotti Journal of Neuroscience 24 (48), 10924-10940, 2004 | 223 | 2004 |
Galantamine is an allosterically potentiating ligand of the human α4/β2 nAChR M Samochocki, M Zerlin, R Jostock, PJ Groot Kormelink, W Luyten, ... Acta Neurologica Scandinavica 102, 68-73, 2000 | 204 | 2000 |
Pentameric concatenated (α4)2(β2)3 and (α4)3(β2)2 nicotinic acetylcholine receptors: subunit arrangement determines functional expression AL Carbone, M Moroni, PJ Groot‐Kormelink, I Bermudez British journal of pharmacology 156 (6), 970-981, 2009 | 147 | 2009 |
A reporter mutation approach shows incorporation of the “orphan” subunit β3 into a functional nicotinic receptor PJ Groot-Kormelink, WHML Luyten, D Colquhoun, LG Sivilotti Journal of Biological Chemistry 273 (25), 15317-15320, 1998 | 132 | 1998 |
The activation mechanism of α1 homomeric glycine receptors M Beato, PJ Groot-Kormelink, D Colquhoun, LG Sivilotti Journal of Neuroscience 24 (4), 895-906, 2004 | 115 | 2004 |
Openings of the rat recombinant α1 homomeric glycine receptor as a function of the number of agonist molecules bound M Beato, PJ Groot-Kormelink, D Colquhoun, LG Sivilotti The Journal of general physiology 119 (5), 443-466, 2002 | 92 | 2002 |
Formation of functional α3β4α5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach PJ Groot‐Kormelink, JP Boorman, LG Sivilotti British journal of pharmacology 134 (4), 789-796, 2001 | 84 | 2001 |
Human α3β4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells P Krashia, M Moroni, S Broadbent, G Hofmann, S Kracun, M Beato, ... PloS one 5 (10), e13611, 2010 | 83 | 2010 |
Cholinergic drugs potentiate human nicotinic α4β2 acetylcholine receptors by a competitive mechanism CJGM Smulders, R Zwart, I Bermudez, RGDM van Kleef, ... European journal of pharmacology 509 (2-3), 97-108, 2005 | 70 | 2005 |
Incorporation of the β3 subunit has a dominant-negative effect on the function of recombinant central-type neuronal nicotinic receptors S Broadbent, PJ Groot-Kormelink, PA Krashia, PC Harkness, NS Millar, ... Molecular pharmacology 70 (4), 1350-1357, 2006 | 69 | 2006 |
Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits β3 and β4 and expression of seven nAChR subunits in the … PJG Kormelink, WHML Luyten FEBS letters 400 (3), 309-314, 1997 | 69 | 1997 |
Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation V Burzomato, PJ Groot-Kormelink, LG Sivilotti, M Beato Receptors and Channels 9 (6), 353-361, 2003 | 66 | 2003 |
Proprotein processing activity and cleavage site selectivity of the Kex2‐like endoprotease PACE4 JWM Creemers, PJG Kormelink, AJM Roebroek, K Nakayama, ... FEBS letters 336 (1), 65-69, 1993 | 61 | 1993 |
Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors PJ Groot-Kormelink, SD Broadbent, JP Boorman, LG Sivilotti The Journal of general physiology 123 (6), 697-708, 2004 | 53 | 2004 |
Single‐channel study of the spasmodic mutation α1A52S in recombinant rat glycine receptors AJR Plested, PJ Groot‐Kormelink, D Colquhoun, LG Sivilotti The Journal of physiology 581 (1), 51-73, 2007 | 52 | 2007 |
Constraining the expression of nicotinic acetylcholine receptors by using pentameric constructs PJ Groot-Kormelink, S Broadbent, M Beato, LG Sivilotti Molecular pharmacology 69 (2), 558-563, 2006 | 50 | 2006 |
Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates PJ Groot-Kormelink, L Fawcett, PD Wright, M Gosling, TC Kent BMC immunology 13, 1-9, 2012 | 49 | 2012 |
Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of α1 glycine receptors in HEK293 cells PJ Groot-Kormelink, M Beato, C Finotti, RJ Harvey, LG Sivilotti Journal of neuroscience methods 113 (2), 207-214, 2002 | 48 | 2002 |
The effects of β3 subunit incorporation on the pharmacology and single channel properties of oocyte-expressed human α3β4 neuronal nicotinic receptors JP Boorman, M Beato, PJ Groot-Kormelink, SD Broadbent, LG Sivilotti Journal of Biological Chemistry 278 (45), 44033-44040, 2003 | 34 | 2003 |
Variomics screen identifies the re-entrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation A Bill, MO Popa, MT van Diepen, A Gutierrez, S Lilley, M Velkova, ... Journal of Biological Chemistry 290 (2), 889-903, 2015 | 33 | 2015 |