Paul J Groot-Kormelink
Paul J Groot-Kormelink
Verified email at novartis.com
TitleCited byYear
Single-channel behavior of heteromeric α1β glycine receptors: an attempt to detect a conformational change before the channel opens
V Burzomato, M Beato, PJ Groot-Kormelink, D Colquhoun, LG Sivilotti
Journal of Neuroscience 24 (48), 10924-10940, 2004
1852004
Galantamine is an allosterically potentiating ligand of the human α4/β2 nAChR
M Samochocki, M Zerlin, R Jostock, PJ Groot Kormelink, W Luyten, ...
Acta Neurologica Scandinavica 102, 68-73, 2000
1792000
A reporter mutation approach shows incorporation of the “orphan” subunit β3 into a functional nicotinic receptor
PJ Groot-Kormelink, WHML Luyten, D Colquhoun, LG Sivilotti
Journal of Biological Chemistry 273 (25), 15317-15320, 1998
1171998
Pentameric concatenated (α4)2(β2)3 and (α4)3(β2)2 nicotinic acetylcholine receptors: subunit arrangement determines functional expression
AL Carbone, M Moroni, PJ Groot‐Kormelink, I Bermudez
British journal of pharmacology 156 (6), 970-981, 2009
1062009
The activation mechanism of α1 homomeric glycine receptors
M Beato, PJ Groot-Kormelink, D Colquhoun, LG Sivilotti
Journal of Neuroscience 24 (4), 895-906, 2004
1042004
Openings of the rat recombinant α1 homomeric glycine receptor as a function of the number of agonist molecules bound
M Beato, PJ Groot-Kormelink, D Colquhoun, LG Sivilotti
The Journal of general physiology 119 (5), 443-466, 2002
812002
Formation of functional α3β4α5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach
PJ Groot‐Kormelink, JP Boorman, LG Sivilotti
British journal of pharmacology 134 (4), 789-796, 2001
652001
Cholinergic drugs potentiate human nicotinic α4β2 acetylcholine receptors by a competitive mechanism
CJGM Smulders, R Zwart, I Bermudez, RGDM van Kleef, ...
European journal of pharmacology 509 (2-3), 97-108, 2005
632005
Incorporation of the β3 subunit has a dominant-negative effect on the function of recombinant central-type neuronal nicotinic receptors
S Broadbent, PJ Groot-Kormelink, PA Krashia, PC Harkness, NS Millar, ...
Molecular pharmacology 70 (4), 1350-1357, 2006
592006
Cloning and sequence of full‐length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits β3 and β4 and expression of seven nAChR subunits in the …
PJ Groot Kormelink, WHML Luyten
FEBS letters 400 (3), 309-314, 1997
581997
Human α3β4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells
P Krashia, M Moroni, S Broadbent, G Hofmann, S Kracun, M Beato, ...
PloS one 5 (10), e13611, 2010
562010
Proprotein processing activity and cleavage site selectivity of the Kex2‐like endoprotease PACE4
JWM Creemers, PJG Kormelink, AJM Roebroek, K Nakayama, ...
FEBS letters 336 (1), 65-69, 1993
531993
Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation
V Burzomato, PJ Groot-Kormelink, LG Sivilotti, M Beato
Receptors and Channels 9 (6), 353-361, 2003
512003
Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors
PJ Groot-Kormelink, SD Broadbent, JP Boorman, LG Sivilotti
The Journal of general physiology 123 (6), 697-708, 2004
472004
Constraining the expression of nicotinic acetylcholine receptors by using pentameric constructs
PJ Groot-Kormelink, S Broadbent, M Beato, LG Sivilotti
Molecular pharmacology 69 (2), 558-563, 2006
442006
Single‐channel study of the spasmodic mutation α1A52S in recombinant rat glycine receptors
AJR Plested, PJ Groot‐Kormelink, D Colquhoun, LG Sivilotti
The Journal of physiology 581 (1), 51-73, 2007
432007
Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of α1 glycine receptors in HEK293 cells
PJ Groot-Kormelink, M Beato, C Finotti, RJ Harvey, LG Sivilotti
Journal of neuroscience methods 113 (2), 207-214, 2002
392002
US Food and Drug Administration Approval Summary: Atezolizumab for metastatic non–small cell lung cancer
C Weinstock, S Khozin, D Suzman, L Zhang, S Tang, S Wahby, ...
Clinical Cancer Research 23 (16), 4534-4539, 2017
372017
The effects of β3 subunit incorporation on the pharmacology and single channel properties of oocyte-expressed human α3β4 neuronal nicotinic receptors
JP Boorman, M Beato, PJ Groot-Kormelink, SD Broadbent, LG Sivilotti
Journal of Biological Chemistry 278 (45), 44033-44040, 2003
342003
Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates
PJ Groot-Kormelink, L Fawcett, PD Wright, M Gosling, TC Kent
BMC immunology 13 (1), 57, 2012
312012
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