Prof Gregory L Challis
Prof Gregory L Challis
Dept of Chemistry, Univ of Warwick; Dept of Biochemistry and Molecular Biology, Monash Univ
Verified email at warwick.ac.uk - Homepage
TitleCited byYear
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3 (2)
SD Bentley, KF Chater, AM Cerdeño-Tárraga, GL Challis, NR Thomson, ...
Nature 417 (6885), 141-147, 2002
32182002
PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
B Gust, GL Challis, K Fowler, T Kieser, KF Chater
Proceedings of the National Academy of Sciences 100 (4), 1541-1546, 2003
13702003
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ...
Natural product reports 30 (1), 108-160, 2013
10472013
Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains
GL Challis, J Ravel, CA Townsend
Chemistry & biology 7 (3), 211-224, 2000
7792000
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei
MTG Holden, RW Titball, SJ Peacock, AM Cerdeño-Tárraga, T Atkins, ...
Proceedings of the National Academy of Sciences 101 (39), 14240-14245, 2004
7292004
Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species
GL Challis, DA Hopwood
Proceedings of the National Academy of Sciences 100 (suppl 2), 14555-14561, 2003
6482003
Discovery of microbial natural products by activation of silent biosynthetic gene clusters
PJ Rutledge, GL Challis
Nature reviews microbiology 13 (8), 509-523, 2015
4062015
Discovery of a new peptide natural product by Streptomyces coelicolor genome mining
S Lautru, RJ Deeth, LM Bailey, GL Challis
Nature chemical biology 1 (5), 265-269, 2005
3582005
Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens
MW Silby, AM Cerdeño-Tárraga, GS Vernikos, SR Giddens, RW Jackson, ...
Genome biology 10 (5), R51, 2009
3432009
A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases
GL Challis
Chembiochem 6 (4), 601-611, 2005
2862005
Strategies for the discovery of new natural products by genome mining
M Zerikly, GL Challis
ChemBioChem 10 (4), 625-633, 2009
2832009
Mining microbial genomes for new natural products and biosynthetic pathways
GL Challis
Microbiology 154 (6), 1555-1569, 2008
2692008
Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
L Laureti, L Song, S Huang, C Corre, P Leblond, GL Challis, B Aigle
Proceedings of the National Academy of Sciences 108 (15), 6258-6263, 2011
2652011
The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081
NR Thomson, S Howard, BW Wren, MTG Holden, L Crossman, GL Challis, ...
PLoS genetics 2 (12), 2006
2242006
Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3 (2): new mechanisms for chain initiation and termination in modular multienzymes
AM Cerdeño, MJ Bibb, GL Challis
Chemistry & biology 8 (8), 817-829, 2001
1972001
Genome mining for novel natural product discovery
GL Challis
Journal of medicinal chemistry 51 (9), 2618-2628, 2008
1932008
Identification of a Cluster of Genes that Directs Desferrioxamine Biosynthesis in Streptomyces c oelicolor M145
F Barona-Gómez, U Wong, AE Giannakopulos, PJ Derrick, GL Challis
Journal of the American Chemical Society 126 (50), 16282-16283, 2004
1922004
Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide …
GL Challis, J Ravel
FEMS microbiology letters 187 (2), 111-114, 2000
1912000
Type III Polyketide Synthase β-Ketoacyl-ACP Starter Unit and Ethylmalonyl-CoA Extender Unit Selectivity Discovered by Streptomyces coelicolor Genome Mining
L Song, F Barona-Gomez, C Corre, L Xiang, DW Udwary, MB Austin, ...
Journal of the American Chemical Society 128 (46), 14754-14755, 2006
1552006
The dynamic architecture of the metabolic switch in Streptomyces coelicolor
K Nieselt, F Battke, A Herbig, P Bruheim, A Wentzel, ØM Jakobsen, ...
BMC genomics 11 (1), 10, 2010
1532010
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Articles 1–20