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Thomas J. McCorvie
Thomas J. McCorvie
Postdoctoral Research Scientist
Verified email at newcastle.ac.uk
Title
Cited by
Cited by
Year
Structural basis of homologous recombination
ZX Sun S, McCorvie TJ, Yates LA
Cellular and Molecular Life Sciences, 2019
117*2019
Isomerization of BRCA1–BARD1 promotes replication fork protection
M Daza-Martin, K Starowicz, M Jamshad, S Tye, GE Ronson, HL MacKay, ...
Nature 571 (7766), 521-527, 2019
1052019
Structural basis for ligand-dependent dimerization of phenylalanine hydroxylase regulatory domain
D Patel, J Kopec, F Fitzpatrick, TJ McCorvie, WW Yue
Scientific reports 6 (1), 23748, 2016
722016
Structural basis of glycogen branching enzyme deficiency and pharmacologic rescue by rational peptide design
DS Froese, A Michaeli, TJ McCorvie, T Krojer, M Sasi, E Melaev, ...
Human molecular genetics 24 (20), 5667-5676, 2015
712015
Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase
TJ McCorvie, J Kopec, AL Pey, F Fitzpatrick, D Patel, R Chalk, L Shrestha, ...
Human Molecular Genetics 25 (11), 2234-2244, 2016
602016
Inter-domain communication of human cystathionine β-synthase: structural basis of S-adenosyl-L-methionine activation
TJ McCorvie, J Kopec, SJ Hyung, F Fitzpatrick, X Feng, D Termine, ...
Journal of Biological Chemistry 289 (52), 36018-36030, 2014
572014
Misfolding of galactose 1-phosphate uridylyltransferase can result in type I galactosemia
TJ McCorvie, TJ Gleason, JL Fridovich-Keil, DJ Timson
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (8 …, 2013
542013
Structural insights into the MMACHC-MMADHC protein complex involved in vitamin B12 trafficking
DS Froese, J Kopec, F Fitzpatrick, M Schuller, TJ McCorvie, R Chalk, ...
Journal of Biological Chemistry 290 (49), 29167-29177, 2015
462015
Structural and molecular biology of type I galactosemia: Disease‐associated mutations
TJ McCorvie, DJ Timson
IUBMB life 63 (11), 949-954, 2011
392011
Altered cofactor binding affects stability and activity of human UDP-galactose 4′-epimerase: implications for type III galactosemia
TJ McCorvie, Y Liu, A Frazer, TJ Gleason, JL Fridovich-Keil, DJ Timson
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (10 …, 2012
342012
The structural and molecular biology of type I galactosemia: Enzymology of galactose 1‐phosphate uridylyltransferase
TJ McCorvie, DJ Timson
IUBMB life 63 (9), 694-700, 2011
332011
Analysis of UDP‐galactose 4′‐epimerase mutations associated with the intermediate form of type III galactosaemia
JS Chhay, CA Vargas, TJ McCorvie, JL Fridovich‐Keil, DJ Timson
Journal of Inherited Metabolic Disease: Official Journal of the Society for …, 2008
282008
In silico prediction of the effects of mutations in the human UDP-galactose 4′-epimerase gene: towards a predictive framework for type III galactosemia
TJ McCorvie, DJ Timson
Gene 524 (2), 95-104, 2013
262013
In vivo and in vitro function of human UDP-galactose 4′-epimerase variants
TJ McCorvie, J Wasilenko, Y Liu, JL Fridovich-Keil, DJ Timson
Biochimie 93 (10), 1747-1754, 2011
222011
Galactosemia: Towards pharmacological chaperones
S Banford, TJ McCorvie, AL Pey, DJ Timson
Journal of Personalized Medicine 11 (2), 106, 2021
202021
Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism
GA Bezerra, WR Foster, HJ Bailey, KG Hicks, SW Sauer, B Dimitrov, ...
IUCrJ 7 (4), 693-706, 2020
202020
The Molecular Dynamics of Trypanosoma brucei UDP‐Galactose 4′‐Epimerase: A Drug Target for African Sleeping Sickness
AJ Friedman, JD Durrant, LCT Pierce, TJ McCorvie, DJ Timson, ...
Chemical biology & drug design 80 (2), 173-181, 2012
172012
Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate
TJ McCorvie, PM Loria, M Tu, S Han, L Shrestha, DS Froese, IM Ferreira, ...
Nature structural & molecular biology 29 (7), 628-638, 2022
112022
UDP-galactose 4-epimerase (GALE)
T McCorvie, D Timson
Handbook of glycosyltransferases and related genes, 2013
112013
The complex machinery of human cobalamin metabolism
TJ McCorvie, D Ferreira, WW Yue, DS Froese
Journal of Inherited Metabolic Disease 46 (3), 406-420, 2023
92023
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