| Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension CD Cox, C Bae, L Ziegler, S Hartley, V Nikolova-Krstevski, PR Rohde, ... Nature communications 7 (1), 1-13, 2016 | 303 | 2016 |
| The N–terminal tail of hERG contains an amphipathic α–helix that regulates channel deactivation CA Ng, MJ Hunter, MD Perry, M Mobli, Y Ke, PW Kuchel, GF King, D Stock, ... PloS one 6 (1), e16191, 2011 | 95 | 2011 |
| Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels PS Tan, MD Perry, CA Ng, JI Vandenberg, AP Hill Journal of General Physiology 140 (3), 293-306, 2012 | 51 | 2012 |
| The S4–S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating CA Ng, MD Perry, PS Tan, AP Hill, PW Kuchel, JI Vandenberg PloS one 7 (2), e31640, 2012 | 47 | 2012 |
| Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11. 1 channels CA Ng, K Phan, AP Hill, JI Vandenberg, MD Perry Journal of Biological Chemistry 289 (37), 25822-25832, 2014 | 43 | 2014 |
| Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2 A Sadrieh, L Domanski, J Pitt-Francis, SA Mann, EC Hodkinson, CA Ng, ... Nature communications 5 (1), 1-11, 2014 | 42 | 2014 |
| Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain–domain interactions Y Ke, CA Ng, MJ Hunter, SA Mann, J Heide, AP Hill, JI Vandenberg Biochemical Journal 454 (1), 69-77, 2013 | 39 | 2013 |
| Getting to the heart of hERG K+ channel gating MD Perry, CA Ng, SA Mann, A Sadrieh, M Imtiaz, AP Hill, JI Vandenberg The Journal of physiology 593 (12), 2575-2585, 2015 | 36 | 2015 |
| High-throughput phenotyping of heteromeric human ether-a-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants CA Ng, MD Perry, W Liang, NJ Smith, B Foo, A Shrier, GL Lukacs, AP Hill, ... Heart rhythm 17 (3), 492-500, 2020 | 35 | 2020 |
| Rescue of protein expression defects may not be enough to abolish the pro‐arrhythmic phenotype of long QT type 2 mutations MD Perry, CA Ng, K Phan, E David, K Steer, MJ Hunter, SA Mann, ... The Journal of physiology 594 (14), 4031-4049, 2016 | 28 | 2016 |
| Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11. 1 channels MD Perry, S Wong, CA Ng, JI Vandenberg Journal of General Physiology 142 (3), 275-288, 2013 | 21 | 2013 |
| Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11. 1 channels Y Ke, MJ Hunter, CA Ng, MD Perry, JI Vandenberg Journal of Biological Chemistry 289 (20), 13782-13791, 2014 | 20 | 2014 |
| Pore helices play a dynamic role as integrators of domain motion during Kv11. 1 channel inactivation gating MD Perry, CA Ng, JI Vandenberg Journal of Biological Chemistry 288 (16), 11482-11491, 2013 | 17 | 2013 |
| High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KV11. 1 KA Kozek, AM Glazer, CA Ng, D Blackwell, CL Egly, LR Vanags, M Blair, ... Heart Rhythm 17 (12), 2180-2189, 2020 | 15 | 2020 |
| Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization MD Perry, CA Ng, MM Mangala, TYM Ng, AD Hines, W Liang, MJO Xu, ... Cardiovascular research 116 (8), 1434-1445, 2020 | 14 | 2020 |
| Insights into hERG K+ channel structure and function from NMR studies CA Ng, AM Torres, PW Kuchel, JI Vandenberg European Biophysics Journal 42 (1), 71-79, 2013 | 12 | 2013 |
| Structural characterisation of PinA WW domain and a comparison with other group IV WW domains, Pin1 and Ess1 CA Ng, Y Kato, M Tanokura, RTC Brownlee Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (9), 1208-1214, 2008 | 9 | 2008 |
| C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11. 1 channels CA Ng, Y Ke, MD Perry, PS Tan, AP Hill, JI Vandenberg PloS one 8 (10), e77032, 2013 | 8 | 2013 |
| The S1 helix critically regulates the finely tuned gating of Kv11. 1 channels K Phan, CA Ng, E David, D Shishmarev, PW Kuchel, JI Vandenberg, ... Journal of Biological Chemistry 292 (18), 7688-7705, 2017 | 7 | 2017 |
| Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations JV Li, CA Ng, D Cheng, Z Zhou, M Yao, Y Guo, ZY Yu, Y Ramaswamy, ... Communications biology 4 (1), 1-17, 2021 | 5 | 2021 |
Jamie VandenbergProfessor, Victor Chang Cardiac Research InstituteVerified email at victorchang.edu.au
