|GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation|
J Xu, TR Kimball, JN Lorenz, DA Brown, AR Bauskin, R Klevitsky, ...
Circulation research 98 (3), 342-350, 2006
|Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum|
JB Welsh, LM Sapinoso, SG Kern, DA Brown, T Liu, AR Bauskin, RL Ward, ...
Proceedings of the National Academy of Sciences 100 (6), 3410-3415, 2003
|Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1|
H Johnen, S Lin, T Kuffner, DA Brown, VWW Tsai, AR Bauskin, L Wu, ...
Nature medicine 13 (11), 1333-1340, 2007
|Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study|
DA Brown, SN Breit, J Buring, WD Fairlie, AR Bauskin, T Liu, PM Ridker
The Lancet 359 (9324), 2159-2163, 2002
|Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer|
AR Bauskin, DA Brown, T Kuffner, H Johnen, XW Luo, M Hunter, SN Breit
Cancer research 66 (10), 4983-4986, 2006
|Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers|
J Koopmann, P Buckhaults, DA Brown, ML Zahurak, N Sato, N Fukushima, ...
Clinical Cancer Research 10 (7), 2386-2392, 2004
|MIC-1 Serum Level and Genotype Associations with Progress and Prognosis of Colorectal Carcinoma|
DA Brown, RL Ward, P Buckhaults, T Liu, KE Romans, NJ Hawkins, ...
Clinical Cancer Research 9 (7), 2642-2650, 2003
|Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9|
J Koopmann, CNW Rosenzweig, Z Zhang, MI Canto, DA Brown, M Hunter, ...
Clinical Cancer Research 12 (2), 442-446, 2006
|Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells|
T Liu, AR Bauskin, J Zaunders, DA Brown, S Pankurst, PJ Russell, ...
Cancer research 63 (16), 5034-5040, 2003
|The transforming growth factor-β superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women|
DA Brown, AG Moore, WD Fairlie, AR Bauskin, PK Brown, MLC Munier, ...
Journal of Clinical Endocrinology & Metabolism 85 (12), 4781, 2000
|The TGF-β superfamily cytokine, MIC-1/GDF15: A pleotrophic cytokine with roles in inflammation, cancer and metabolism|
SN Breit, H Johnen, AD Cook, VWW Tsai, MG Mohammad, T Kuffner, ...
Growth factors 29 (5), 187-195, 2011
|Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis|
DA Brown, PE Sawchenko
Journal of Comparative Neurology 502 (2), 236-260, 2007
|Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation|
H Yang, Z Filipovic, D Brown, SN Breit, LT Vassilev
Molecular Cancer Therapeutics 2 (10), 1023-1029, 2003
|Macrophage inhibitory cytokine‐1 (MIC‐1/GDF15): a new marker of all‐cause mortality|
FE Wiklund, AM Bennet, PKE Magnusson, UK Eriksson, F Lindmark, L Wu, ...
Aging cell 9 (6), 1057-1064, 2010
|The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome|
AR Bauskin, DA Brown, S Junankar, KK Rasiah, S Eggleton, M Hunter, ...
Cancer research 65 (6), 2330-2336, 2005
|The propeptide of macrophage inhibitory cytokine (MIC‐1), a TGF‐β superfamily member, acts as a quality control determinant for correctly folded MIC‐1|
AR Bauskin, HP Zhang, WD Fairlie, XY He, PK Russell, AG Moore, ...
The EMBO journal 19 (10), 2212-2220, 2000
|Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer|
DA Brown, F Lindmark, P Stattin, K Bälter, HO Adami, SL Zheng, J Xu, ...
Clinical Cancer Research 15 (21), 6658-6664, 2009
|Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis|
DA Brown, C Stephan, RL Ward, M Law, M Hunter, AR Bauskin, J Amin, ...
Clinical Cancer Research 12 (1), 89-96, 2006
|Macrophage Inhibitory Cytokine 1 (MIC-1/GDF15) Decreases Food Intake, Body Weight and Improves Glucose Tolerance in Mice on Normal & Obesogenic Diets|
L Macia, VWW Tsai, AD Nguyen, H Johnen, T Kuffner, YC Shi, S Lin, ...
PLoS ONE 7 (4), e34868, 2012
|TGF-b Superfamily Cytokine MIC-1/GDF15 Is a Physiological Appetite and Body Weight Regulator|
VWW Tsai, L Macia, H Johnen, T Kuffner, R Manadhar, SB Jørgensen, ...
PLOS ONE 8 (2), e55174, 2013