Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers JR Mayers, ME Torrence, LV Danai, T Papagiannakopoulos, ... Science 353 (6304), 1161-1165, 2016 | 535 | 2016 |
A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway M Mohseni, J Sun, A Lau, S Curtis, J Goldsmith, VL Fox, C Wei, M Frazier, ... Nature Cell Biology 16 (1), 108-117, 2014 | 333 | 2014 |
Aspartate is an endogenous metabolic limitation for tumour growth LB Sullivan, A Luengo, LV Danai, LN Bush, FF Diehl, AM Hosios, AN Lau, ... Nature Cell Biology 20 (7), 782-788, 2018 | 287 | 2018 |
Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia KA Tropea, E Leder, M Aslam, AN Lau, DM Raiser, JH Lee, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 302 (9 …, 2012 | 263 | 2012 |
Tumor‐propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis AN Lau, SJ Curtis, CM Fillmore, SP Rowbotham, M Mohseni, DE Wagner, ... The EMBO journal 33 (5), 468-481, 2014 | 237 | 2014 |
Low glycaemic diets alter lipid metabolism to influence tumour growth EC Lien, AM Westermark, Y Zhang, C Yuan, Z Li, AN Lau, KM Sapp, ... Nature 599 (7884), 302-307, 2021 | 170 | 2021 |
Primary tumor genotype is an important determinant in identification of lung cancer propagating cells SJ Curtis, KW Sinkevicius, D Li, AN Lau, RR Roach, R Zamponi, ... Cell Stem Cell 7 (1), 127-133, 2010 | 160 | 2010 |
Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci SJ Zacharek, CM Fillmore, AN Lau, DW Gludish, A Chou, JWK Ho, ... Cell Stem Cell 9 (3), 272-281, 2011 | 152 | 2011 |
Cytosolic aspartate availability determines cell survival when glutamine is limiting HF Alkan, KE Walter, A Luengo, CT Madreiter-Sokolowski, S Stryeck, ... Cell Metabolism 28 (5), 706-720. e6, 2018 | 148 | 2018 |
Altered exocrine function can drive adipose wasting in early pancreatic cancer LV Danai, A Babic, MH Rosenthal, EA Dennstedt, A Muir, EC Lien, ... Nature 558 (7711), 600-604, 2018 | 129 | 2018 |
Stem cells and regenerative medicine in lung biology and diseases AN Lau, M Goodwin, CF Kim, DJ Weiss Molecular Therapy 20 (6), 1116-1130, 2012 | 115 | 2012 |
Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance S Dalin, MR Sullivan, AN Lau, B Grauman-Boss, HS Mueller, E Kreidl, ... Cancer research 79 (22), 5723-5733, 2019 | 113 | 2019 |
Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression R Francescone, DB Vendramini-Costa, J Franco-Barraza, J Wagner, ... Cancer Discovery 11 (2), 446-479, 2021 | 109 | 2021 |
Horse domestication and conservation genetics of Przewalski's horse inferred from sex chromosomal and autosomal sequences AN Lau, L Peng, H Goto, L Chemnick, OA Ryder, KD Makova Molecular Biology and Evolution 26 (1), 199-208, 2009 | 91 | 2009 |
Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis KW Sinkevicius, C Kriegel, KJ Bellaria, J Lee, AN Lau, KT Leeman, ... Proceedings of the National Academy of Sciences 111 (28), 10299-10304, 2014 | 90 | 2014 |
Metabolism in the tumor microenvironment AN Lau, MG Vander Heiden Annual Review of Cancer Biology 4, 17-40, 2020 | 86 | 2020 |
JAK2/IDH-mutant–driven myeloproliferative neoplasm is sensitive to combined targeted inhibition AS McKenney, AN Lau, AVH Somasundara, B Spitzer, AM Intlekofer, ... The Journal of Clinical Investigation 128 (2), 2018 | 77 | 2018 |
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma AN Lau, Z Li, LV Danai, AM Westermark, AM Darnell, R Ferreira, ... Elife 9, e56782, 2020 | 70 | 2020 |
Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells C Tian, Y Huang, KR Clauser, S Rickelt, AN Lau, SA Carr, ... Nature communications 12 (1), 2328, 2021 | 50 | 2021 |
Isolation and characterization of distal lung progenitor cells B Driscoll, A Kikuchi, AN Lau, J Lee, R Reddy, E Jesudason, CF Kim, ... Somatic Stem Cells: Methods and Protocols, 109-122, 2012 | 44 | 2012 |