| A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera C James, V Ugo, JP Le Couédic, J Staerk, F Delhommeau, C Lacout, ... nature 434 (7037), 1144-1148, 2005 | 4535 | 2005 |
| Mutation in TET2 in Myeloid Cancers F Delhommeau, S Dupont, VD Valle, C James, S Trannoy, A Massé, ... New England Journal of Medicine 360 (22), 2289-2301, 2009 | 2157 | 2009 |
| Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis AG Fraser, C James, GI Evan, MO Hengartner Current Biology 9 (6), 292-302, 1999 | 320 | 1999 |
| The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera S Dupont, A Massé, C James, I Teyssandier, Y Lécluse, F Larbret, V Ugo, ... Blood, The Journal of the American Society of Hematology 110 (3), 1013-1021, 2007 | 231 | 2007 |
| Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets EC Josefsson, C James, KJ Henley, MA Debrincat, KL Rogers, ... Journal of Experimental Medicine 208 (10), 2017-2031, 2011 | 207 | 2011 |
| A JAK2 mutation in myeloproliferative disorders: pathogenesis and therapeutic and scientific prospects C James, V Ugo, N Casadevall, SN Constantinescu, W Vainchenker Trends in molecular medicine 11 (12), 546-554, 2005 | 194 | 2005 |
| Detection of JAK2 V617F as a first intention diagnostic test for erythrocytosis C James, F Delhommeau, C Marzac, I Teyssandier, JP Le Couédic, ... Leukemia 20 (2), 350-353, 2006 | 181 | 2006 |
| Human Bak induces cell death in Schizosaccharomyces pombe with morphological changes similar to those with apoptosis in mammalian cells B Ink, M Zörnig, B Baum, N Hajibagheri, C James, T Chittenden, G Evan Molecular and cellular biology, 1997 | 179 | 1997 |
| CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9 C James, S Gschmeissner, A Fraser, GI Evan Current Biology 7 (4), 246-252, 1997 | 178 | 1997 |
| Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor–induced thrombocytopenia MJ Bishton, SJ Harrison, BP Martin, N McLaughlin, C James, ... Blood, The Journal of the American Society of Hematology 117 (13), 3658-3668, 2011 | 144 | 2011 |
| Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells L Garçon, C Rivat, C James, C Lacout, V Camara-Clayette, V Ugo, ... Blood 108 (5), 1551-1554, 2006 | 141 | 2006 |
| Analysis of the Ten-Eleven Translocation 2 (TET2) gene in familial myeloproliferative neoplasms C Saint-Martin, G Leroy, F Delhommeau, G Panelatti, S Dupont, C James, ... Blood, The Journal of the American Society of Hematology 114 (8), 1628-1632, 2009 | 134 | 2009 |
| Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis R Chaligné, C James, C Tonetti, R Besancenot, JP Le Couédic, F Fava, ... Blood, The Journal of the American Society of Hematology 110 (10), 3735-3743, 2007 | 127 | 2007 |
| The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneity C James, F Mazurier, S Dupont, R Chaligne, I Lamrissi-Garcia, M Tulliez, ... Blood, The Journal of the American Society of Hematology 112 (6), 2429-2438, 2008 | 124 | 2008 |
| Oncogenic mechanisms in myeloproliferative disorders F Delhommeau, DF Pisani, C James, N Casadevall, S Constantinescu, ... Cellular and Molecular Life Sciences CMLS 63, 2939-2953, 2006 | 111 | 2006 |
| Vascular endothelial cell expression of JAK2V617F is sufficient to promote a pro-thrombotic state due to increased P-selectin expression A Guy, V Gourdou-Latyszenok, N Le Lay, C Peghaire, B Kilani, JV Dias, ... Haematologica 104 (1), 70, 2019 | 102 | 2019 |
| Mcl-1 and Bcl-xL coordinately regulate megakaryocyte survival MA Debrincat, EC Josefsson, C James, KJ Henley, S Ellis, M Lebois, ... Blood, The Journal of the American Society of Hematology 119 (24), 5850-5858, 2012 | 90 | 2012 |
| Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function MJ White, SM Schoenwaelder, EC Josefsson, KE Jarman, KJ Henley, ... Blood, The Journal of the American Society of Hematology 119 (18), 4283-4290, 2012 | 85 | 2012 |
| The JAK2V617F mutation in polycythemia vera and other myeloproliferative disorders: one mutation for three diseases? C James ASH Education Program Book 2008 (1), 69-75, 2008 | 76 | 2008 |
| Analysis of 339 pregnancies in 181 women with 13 different forms of inherited thrombocytopenia P Noris, N Schlegel, C Klersy, PG Heller, E Civaschi, N Pujol-Moix, ... Haematologica 99 (8), 1387, 2014 | 73 | 2014 |
