| Proteomic screening and lasso regression reveal differential signaling in insulin and insulin-like growth factor I (IGF1) pathways C Erdem, AM Nagle, AJ Casa, BC Litzenburger, Y Wang, DL Taylor, ... Molecular & Cellular Proteomics 15 (9), 3045-3057, 2016 | 29 | 2016 |
| A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses SM Gross, MA Dane, RL Smith, KL Devlin, IC McLean, DS Derrick, ... Communications Biology 5 (1), 1-20, 2022 | 17* | 2022 |
| A scalable, open-source implementation of a large-scale mechanistic model for single cell proliferation and death signaling C Erdem, A Mutsuddy, EM Bensman, WB Dodd, MM Saint-Antoine, ... Nature Communications 13 (1), 1-18, 2022 | 11 | 2022 |
| Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells C Erdem, AV Lee, DL Taylor, TR Lezon PLOS Computational Biology 17 (6), e1009125, 2021 | 4* | 2021 |
| MOBILE pipeline enables identification of context-specific networks and regulatory mechanisms C Erdem, SM Gross, LM Heiser, MR Birtwistle Nature Communications 14 (1), 3991, 2023 | 2* | 2023 |
| MEMMAL: A tool for expanding large-scale mechanistic models with machine learned associations and big datasets C Erdem, MR Birtwistle Frontiers in Systems Biology 3, 1099413, 2023 | 2 | 2023 |
| Mathematical Modeling of Behcet's Disease: A Dynamical Systems Approach C Erdem, Y Bozkurt, B Erman, A GÜL, A Demir Journal of Biological Systems 23 (02), 231-257, 2015 | 1 | 2015 |
| Intracellular negative regulators of RTK-Ras-ERK signaling alter breast cancer perception of metastatic niche-derived growth factors V Murthy, C Erdem, J Copperman, M Birtwistle, A Davies Cancer Research 84 (6_Supplement), 5535-5535, 2024 | | 2024 |
| Computational speed-up of large-scale, single-cell model simulations via a fully integrated SBML-based format A Mutsuddy, C Erdem, JR Huggins, M Salim, D Cook, N Hobbs, FA Feltus, ... Bioinformatics Advances 3 (1), vbad039, 2023 | | 2023 |
| Design, Engineering, and Structural Prediction of Peptides and Proteins D Samanta, C Erdem, P Tamamis 2021 AIChE Annual Meeting, 2021 | | 2021 |
| Big Data+ Machine Learning+ Mechanistic Models= Mechanistic Precision Medicine C Erdem 2021 AIChE Annual Meeting, 2021 | | 2021 |
| Mesowestern Blot: Simultaneous Analysis of Hundreds of Sub-Microliter Lysates CO Zadeh, JR Huggins, BC Westbury, WR Interiano, SA Phillips, C Erdem, ... | | 2021 |
| Towards Integrative Mechanistic Models of Mammalian Cell Responses to Anti-Cancer Drug Combinations C Erdem, A Mutsuddy, W Dodd, MR Birtwistle 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
| Integrating Multi-Omics Datasets and Big Mechanistic Models to Select Experiments Intelligently C Erdem 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
| EMPLOYING QUANTITATIVE SYSTEMS PHARMACOLOGY TO CHARACTERIZE DIFFERENCES IN IGF1 AND INSULIN SIGNALING PATHWAYS IN BREAST CANCER C ERDEM University of Pittsburgh, 2018 | | 2018 |
| Abstract B158: Exploiting IGF1R pathway activation as a therapeutic strategy for E-cadherin deficient breast cancers AM Nagle, C Erdem, K Levine, C Sotiriou, O Metzger, DL Taylor, T Lezon, ... Molecular Cancer Therapeutics 17 (1_Supplement), B158-B158, 2018 | | 2018 |
| Determining the role of E-cadherin in regulating IGF1 signaling in breast cancer: An interaction predicted by large-scale modeling AM Nagle, C Erdem, YF Wang, K Levine, T Katz, DL Taylor, AV Lee, ... Cancer Research 76 (14_Supplement), 1880-1880, 2016 | | 2016 |
| IGF-I and Insulin Repress MAPK Signaling in Her2-Amplified Breast Cancer Cell Lines AM Nagle, C Erdem, YF Wang, S Iadevaia, BC Litzenburger, A Casa, Y Lu, ... Late-breaking Membrane and Intracellular Signaling, LBT-052-LBT-052, 2015 | | 2015 |
| Unraveling novel differential responses to insulin and insulin-like growth factor I in breast cancer by computational modeling C Erdem, AM Nagle, DL Taylor, AV Lee, TR Lezon MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
| Mathematical Modeling of Behçet's Disease C Erdem Koç University, 2012 | | 2012 |
Adrian V. LeeProfessor of Pharmacology, University of PittsburghVerified email at pitt.edu
