Wouter de Laat

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Elzo de WitNetherlands Cancer InstituteVerified email at nki.nl
Peter Hugo Lodewijk KrijgerHubrecht InstituteVerified email at hubrecht.eu
Geert GeevenHubrecht Institute-KNAW & University Medical Centre UtrechtVerified email at hubrecht.eu
Harmen van de WerkenComputational Biology & Bioinformatics in Immunology and cancer (CBBI), Departments of ImmunologyVerified email at erasmusmc.nl
Bas van SteenselNetherlands Cancer InstituteVerified email at nki.nl
Valerio BianchiEnza ZadenVerified email at enzazaden.nl
Duboule DenisProfessor of Genetics, Collège de France, Paris, EPFL Lausanne and University of GenevaVerified email at unige.ch
Daan NoordermeerUniversity Paris-Saclay - Institute for Integrative Biology of the Cell, Gif-sur-Yvette, FranceVerified email at i2bc.paris-saclay.fr
Wouter MeulemanPrincipal Investigator, Altius Institute for Biomedical SciencesVerified email at altius.org
Lodewyk WesselsProfessor of Computational Cancer BiologyVerified email at nki.nl
Job DekkerUniversity of Massachusetts Medical School, Howard Hughes Medical InstituteVerified email at umassmed.edu
Pieter Van VlierbergheFull Professor, Ghent University, Ghent, BelgiumVerified email at ugent.be
Sónia MeloInstitute for Research and Innovation in Health i3SVerified email at ipatimup.pt
Nicolas LeveilleAcademisch Medisch Centrum (AMC)Verified email at amc.nl
Reuven AgamiVerified email at nki.nl
P BarnettDr. P. Barnett, Heart Failure Research Center, AMC, University of AmsterdamVerified email at amc.uva.nl
Malou van den BoogaardUniversity of AmsterdamVerified email at amsterdamumc.nl
Andrew StubbsAssociate Professor, Erasmus MCVerified email at erasmusmc.nl
Karin Pike-OverzetLeiden University Medical CenterVerified email at lumc.nl
Frank StaalIHB, Molecular Stem Cell Biology LUMC, Universiteit LeidenVerified email at lumc.nl

Wouter de Laat

Unknown affiliation

Verified email at hubrecht.eu


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions L Guelen, L Pagie, E Brasset, W Meuleman, MB Faza, W Talhout, ... Nature 453 (7197), 948-951, 2008	2110	2008
Looping and interaction between hypersensitive sites in the active β-globin locus B Tolhuis, RJ Palstra, E Splinter, F Grosveld, W De Laat Molecular cell 10 (6), 1453-1465, 2002	1701	2002
Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C) M Simonis, P Klous, E Splinter, Y Moshkin, R Willemsen, E De Wit, ... Nature genetics 38 (11), 1348-1354, 2006	1617	2006
Molecular mechanism of nucleotide excision repair WL de Laat, NGJ Jaspers, JHJ Hoeijmakers Genes & development 13 (7), 768-785, 1999	1467	1999
A decade of 3C technologies: insights into nuclear organization E De Wit, W De Laat Genes & development 26 (1), 11-24, 2012	893	2012
CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus E Splinter, H Heath, J Kooren, RJ Palstra, P Klous, F Grosveld, N Galjart, ... Genes & development 20 (17), 2349-2354, 2006	884	2006
Quantitative analysis of chromosome conformation capture assays (3C-qPCR) H Hagege, P Klous, C Braem, E Splinter, J Dekker, G Cathala, W De Laat, ... Nature protocols 2 (7), 1722-1733, 2007	753	2007
A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia S Gröschel, MA Sanders, R Hoogenboezem, E de Wit, BAM Bouwman, ... Cell 157 (2), 369-381, 2014	694	2014
The β-globin nuclear compartment in development and erythroid differentiation RJ Palstra, B Tolhuis, E Splinter, R Nijmeijer, F Grosveld, W de Laat Nature genetics 35 (2), 190-194, 2003	694	2003
Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease AM Sijbers, WL De Laat, RR Ariza, M Biggerstaff, YF Wei, JG Moggs, ... Cell 86 (5), 811-822, 1996	680	1996
CTCF binding polarity determines chromatin looping E de Wit, ESM Vos, SJB Holwerda, C Valdes-Quezada, MJAM Verstegen, ... Molecular cell 60 (4), 676-684, 2015	643	2015
Topology of mammalian developmental enhancers and their regulatory landscapes W De Laat, D Duboule Nature 502 (7472), 499-506, 2013	579	2013
eRNAs are required for p53-dependent enhancer activity and gene transcription CA Melo, J Drost, PJ Wijchers, H van de Werken, E de Wit, JAFO Vrielink, ... Molecular cell 49 (3), 524-535, 2013	568	2013
A regulatory archipelago controls Hox genes transcription in digits T Montavon, N Soshnikova, B Mascrez, E Joye, L Thevenet, E Splinter, ... Cell 147 (5), 1132-1145, 2011	549	2011
Spatial organization of gene expression: the active chromatin hub W de Laat, F Grosveld Chromosome Research 11, 447-459, 2003	473	2003
The dynamic architecture of Hox gene clusters D Noordermeer, M Leleu, E Splinter, J Rougemont, W De Laat, ... Science 334 (6053), 222-225, 2011	471	2011
The active spatial organization of the β-globin locus requires the transcription factor EKLF R Drissen, RJ Palstra, N Gillemans, E Splinter, F Grosveld, S Philipsen, ... Genes & development 18 (20), 2485-2490, 2004	466	2004
DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair WL De Laat, E Appeldoorn, K Sugasawa, E Weterings, NGJ Jaspers, ... Genes & development 12 (16), 2598-2609, 1998	461	1998
Robust 4C-seq data analysis to screen for regulatory DNA interactions HJG Van De Werken, G Landan, SJB Holwerda, M Hoichman, P Klous, ... Nature methods 9 (10), 969-972, 2012	431	2012
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia I Homminga, R Pieters, AW Langerak, JJ de Rooi, A Stubbs, M Verstegen, ... Cancer cell 19 (4), 484-497, 2011	402	2011

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