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Dominic De Nardo
Dominic De Nardo
Group Leader, Monash Biomedicine Discovery Institute, Monash University
Verified email at monash.edu - Homepage
Title
Cited by
Cited by
Year
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
J Xue, SV Schmidt, J Sander, A Draffehn, W Krebs, I Quester, D De Nardo, ...
Immunity 40 (2), 274-288, 2014
16752014
The adaptor ASC has extracellular and'prionoid'activities that propagate inflammation
BS Franklin, L Bossaller, D De Nardo, JM Ratter, A Stutz, G Engels, ...
Nature immunology 15 (8), 727-737, 2014
6622014
Toll-like receptors: activation, signalling and transcriptional modulation
D De Nardo
Cytokine 74 (2), 181-189, 2015
4022015
NLRP3 inflammasomes link inflammation and metabolic disease
D De Nardo, E Latz
Trends in immunology 32 (8), 373-379, 2011
3972011
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3
D De Nardo, LI Labzin, H Kono, R Seki, SV Schmidt, M Beyer, D Xu, ...
Nature immunology 15 (2), 152-160, 2014
3642014
The inflammasomes and autoinflammatory syndromes
L Broderick, D De Nardo, BS Franklin, HM Hoffman, E Latz
Annual Review of Pathology: Mechanisms of Disease 10, 395-424, 2015
2522015
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G Núñez, ...
Proceedings of the National Academy of Sciences 114 (6), E961-E969, 2017
2502017
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
S Zimmer, A Grebe, SS Bakke, N Bode, B Halvorsen, T Ulas, M Skjelland, ...
Science translational medicine 8 (333), 333ra50-333ra50, 2016
2502016
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
SL Masters, V Lagou, I Jéru, PJ Baker, L Van Eyck, DA Parry, D Lawless, ...
Science translational medicine 8 (332), 332ra45-332ra45, 2016
2452016
New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease
D De Nardo, CM De Nardo, E Latz
The American journal of pathology 184 (1), 42-54, 2014
1812014
TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS
CH Yu, S Davidson, CR Harapas, JB Hilton, MJ Mlodzianoski, ...
Cell 183 (3), 636-649. e18, 2020
1662020
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β
ML Kim, JJ Chae, YH Park, D De Nardo, RA Stirzaker, HJ Ko, H Tye, ...
Journal of Experimental Medicine 212 (6), 927-938, 2015
1162015
Signaling crosstalk during sequential TLR4 and TLR9 activation amplifies the inflammatory response of mouse macrophages
D De Nardo, CM De Nardo, T Nguyen, JA Hamilton, GM Scholz
The Journal of Immunology 183 (12), 8110-8118, 2009
1162009
The mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and-7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1β activation
JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ...
Cell reports 25 (9), 2339-2353. e4, 2018
1142018
A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever
F Moghaddas, R Llamas, D De Nardo, H Martinez-Banaclocha, ...
Annals of the rheumatic diseases 76 (12), 2085-2094, 2017
1112017
TBK1 and IKKε act redundantly to mediate STING-induced NF-κB responses in myeloid cells
KR Balka, C Louis, TL Saunders, AM Smith, DJ Calleja, DB D’Silva, ...
Cell reports 31 (1), 107492, 2020
982020
ATF3 is a key regulator of macrophage IFN responses
LI Labzin, SV Schmidt, SL Masters, M Beyer, W Krebs, K Klee, R Stahl, ...
The Journal of Immunology 195 (9), 4446-4455, 2015
872015
Understanding early TLR signaling through the Myddosome
KR Balka, D De Nardo
Journal of leukocyte biology 105 (2), 339-351, 2019
852019
A central role for the Hsp90· Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by Toll-like receptors
D De Nardo, P Masendycz, S Ho, M Cross, AJ Fleetwood, EC Reynolds, ...
Journal of Biological Chemistry 280 (11), 9813-9822, 2005
672005
Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling
D De Nardo, KR Balka, YC Gloria, VR Rao, E Latz, SL Masters
Journal of Biological Chemistry 293 (39), 15195-15207, 2018
652018
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