Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production H Chun, H Im, YJ Kang, Y Kim, JH Shin, W Won, J Lim, Y Ju, YM Park, ... Nature neuroscience 23 (12), 1555-1566, 2020 | 182 | 2020 |
Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer’s disease JH Park, YH Ju, JW Choi, HJ Song, BK Jang, J Woo, H Chun, HJ Kim, ... Science advances 5 (3), eaav0316, 2019 | 134 | 2019 |
Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion TY Kim, S Jeon, Y Jang, L Gotina, J Won, YH Ju, S Kim, MW Jang, W Won, ... Experimental & molecular medicine 53 (5), 956-972, 2021 | 59 | 2021 |
Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease YH Ju, M Bhalla, SJ Hyeon, JE Oh, S Yoo, U Chae, J Kwon, W Koh, J Lim, ... Cell Metabolism 34 (8), 1104-1120. e8, 2022 | 47 | 2022 |
Activation of astrocytic μ-opioid receptor elicits fast glutamate release through TREK-1-containing K2P channel in hippocampal astrocytes DH Woo, JY Bae, MH Nam, H An, YH Ju, J Won, JH Choi, EM Hwang, ... Frontiers in cellular neuroscience 12, 319, 2018 | 43 | 2018 |
Revisiting the role of astrocytic MAOB in Parkinson’s disease MH Nam, M Sa, YH Ju, MG Park, CJ Lee International Journal of Molecular Sciences 23 (8), 4453, 2022 | 20 | 2022 |
Visualizing reactive astrocyte-neuron interaction in Alzheimer’s disease using 11C-acetate and 18F-FDG MH Nam, HY Ko, D Kim, S Lee, YM Park, SJ Hyeon, W Won, JI Chung, ... Brain 146 (7), 2957-2974, 2023 | 18 | 2023 |
Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis W Won, HJ Choi, JY Yoo, D Kim, TY Kim, YH Ju, KD Park, H Lee, SY Jung, ... Experimental & Molecular Medicine 54 (8), 1188-1200, 2022 | 11 | 2022 |
Opto-vTrap, an optogenetic trap for reversible inhibition of vesicular release, synaptic transmission, and behavior J Won, Y Pankratov, MW Jang, S Kim, YH Ju, S Lee, SE Lee, A Kim, ... Neuron 110 (3), 423-435. e4, 2022 | 9 | 2022 |
PyrPeg, a blood–brain-barrier-penetrating two-photon imaging probe, selectively detects Neuritic Plaques, Not Tau Aggregates JW Choi, YH Ju, Y Choi, SJ Hyeon, CG Gadhe, JH Park, MS Kim, S Baek, ... ACS Chemical Neuroscience 11 (12), 1801-1810, 2020 | 8 | 2020 |
Platycodin D prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection in vitro by hindering membrane fusion TY Kim, S Jeon, Y Jang, L Gotina, J Won, YH Ju, S Kim, MW Jang, W Won, ... BioRxiv, 2020.12. 22.423909, 2020 | 6 | 2020 |
Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer’s disease. Sci Adv. 2019; 5: eaav0316 JH Park, YH Ju, JW Choi, HJ Song, BK Jang, J Woo, H Chun, HJ Kim, ... | 5 | |
Visualization of reactive astrocytes in living brain of Alzheimer’s disease patient MH Nam, HY Ko, S Lee, YM Park, SJ Hyeon, W Won, SY Kim, HH Jo, ... BioRxiv, 2021.04. 13.439744, 2021 | 4 | 2021 |
Visualizing cancer-originating acetate uptake through MCT1 in reactive astrocytes in the glioblastoma tumor microenvironment D Kim, HY Ko, JI Chung, YM Park, S Lee, SY Kim, J Kim, JH Chun, ... Neuro-oncology, 2023 | 2 | 2023 |
DDC-Promoter-Driven Chemogenetic Activation of SNpc Dopaminergic Neurons Alleviates Parkinsonian Motor Symptoms DC Seo, YH Ju, JJ Seo, SJ Oh, CJ Lee, SE Lee, MH Nam International Journal of Molecular Sciences 24 (3), 2491, 2023 | 2 | 2023 |
Molecular identification of ALDH1A1 and SIRT2 in the astrocytic putrescine-to-GABA metabolic pathway M Bhalla, JI Shin, YH Ju, YM Park, S Yoo, HB Lee, CJ Lee bioRxiv, 2023.01. 11.523573, 2023 | 2 | 2023 |
Visualizing reactive astrogliosis extends survival in glioblastoma patients HY Ko, JI Chung, D Kim, YM Park, HH Jo, S Lee, SY Kim, J Kim, JH Chun, ... BioRxiv [preprint]. April 14, 2021 | 2 | 2021 |
Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting D Barnett, K Bohmbach, V Grelot, A Charlet, G Dallérac, YH Ju, J Nagai, ... Journal of Neuroscience 43 (45), 7463-7471, 2023 | 1 | 2023 |
Visualizing cancer-originated acetate uptake through MCT1 in reactive astrocytes demarcates tumor border and extends survival in glioblastoma patients HY Ko, JI Chung, D Kim, YM Park, HH Jo, S Lee, SY Kim, J Kim, JH Chun, ... BioRxiv, 2021.04. 13.439750, 2021 | 1 | 2021 |
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via excessive H2O2-production H Chun, Y Kim, YJ Kang, H Im, JH Shin, Y Ju, W Won, YM Park, J Lim, ... IBRO Reports 6, S118, 2019 | 1 | 2019 |