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Shoni Bruell
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The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1
A Sethi, S Bruell, N Patil, MA Hossain, DJ Scott, EJ Petrie, RAD Bathgate, ...
Nature communications 7 (1), 11344, 2016
532016
Familial bilateral cryptorchidism is caused by recessive variants in RXFP2
K Ayers, R Kumar, G Robevska, S Bruell, K Bell, MA Malik, RA Bathgate, ...
Journal of medical genetics 56 (11), 727-733, 2019
382019
Chimeric RXFP1 and RXFP2 receptors highlight the similar mechanism of activation utilizing their N-terminal low-density lipoprotein class A modules
S Bruell, RCK Kong, EJ Petrie, B Hoare, JD Wade, DJ Scott, PR Gooley, ...
Frontiers in Endocrinology 4, 171, 2013
262013
Multi-component mechanism of H2 Relaxin binding to RXFP1 through NanoBRET kinetic analysis
BL Hoare, S Bruell, A Sethi, PR Gooley, MJ Lew, MA Hossain, A Inoue, ...
IScience 11, 93-113, 2019
192019
Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation
RCK Kong, RAD Bathgate, S Bruell, JD Wade, PR Gooley, EJ Petrie
Biochemistry 53 (28), 4537-4548, 2014
182014
Conformational changes in tyrosine 11 of neurotensin are required to activate the neurotensin receptor 1
F Bumbak, T Thomas, BJ Noonan-Williams, TM Vaid, F Yan, ...
ACS Pharmacology & Translational Science 3 (4), 690-705, 2020
172020
Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin
S Bruell, A Sethi, N Smith, DJ Scott, MA Hossain, QP Wu, ZY Guo, ...
Scientific reports 7 (1), 3294, 2017
172017
Using the novel HiBiT tag to label cell surface relaxin receptors for BRET proximity analysis
BL Hoare, M Kocan, S Bruell, DJ Scott, RAD Bathgate
Pharmacology Research & Perspectives 7 (4), e00513, 2019
112019
Structural insights into the unique modes of relaxin-binding and tethered-agonist mediated activation of RXFP1 and RXFP2
A Sethi, S Bruell, T Ryan, F Yan, MH Tanipour, YF Mok, C Draper-Joyce, ...
Journal of Molecular Biology 433 (21), 167217, 2021
72021
Structural insights into the modes of relaxin-binding and tethered-agonist activation of RXFP1 and RXFP2
A Sethi, S Bruell, T Ryan, F Yan, M Tanipour, YF Mok, C Draper-Joyce, ...
bioRxiv, 2021.06. 06.446989, 2021
2021
Mechanism of activation of the relaxin family peptide receptors RXFP1 and RXFP2
SDR Bruell
The University of Melbourne, 2019
2019
Vibrational Medicine: A Closer Look at Homeopathics
SDR Bruell
PIERS Online 3 (1), 87-90, 2007
2007
Reduced hip bone mineral density is associated with high levels of calciprotein particles in patients with Fabry disease
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