John D. Wade
John D. Wade
Professor of Chemical Biology
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Cited by
Cited by
Mammalian Grb2 couple the EGF receptor to the Ras
M Rozakis-Adcock, R Fernley, J Wade, T Pawson, D Bowtell
Nature 363, 83-86, 1993
INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent
J Kumagai, SY Hsu, H Matsumi, JS Roh, P Fu, JD Wade, RAD Bathgate, ...
Journal of Biological Chemistry 277 (35), 31283-31286, 2002
Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene Novel members of the relaxin peptide family
RAD Bathgate, CS Samuel, TCD Burazin, S Layfield, AA Claasz, ...
Journal of Biological Chemistry 277 (2), 1148-1157, 2002
Paracrine regulation of mammalian oocyte maturation and male germ cell survival
K Kawamura, J Kumagai, S Sudo, SY Chun, M Pisarska, H Morita, ...
Proceedings of the National Academy of Sciences 101 (19), 7323-7328, 2004
Amyloid-β peptide (Aβ) neurotoxicity is modulated by the rate of peptide aggregation: Aβ dimers and trimers correlate with neurotoxicity
LW Hung, GD Ciccotosto, E Giannakis, DJ Tew, K Perez, CL Masters, ...
Journal of Neuroscience 28 (46), 11950-11958, 2008
Neurotoxic, redox-competent Alzheimer's β-amyloid is released from lipid membrane by methionine oxidation
KJ Barnham, GD Ciccotosto, AK Tickler, FE Ali, DG Smith, NA Williamson, ...
Journal of Biological Chemistry 278 (44), 42959-42965, 2003
Vasopressin secretion: osmotic and hormonal regulation by the lamina terminalis
MJ McKinley, ML Mathai, RM McAllen, RC McClear, RR Miselis, ...
Journal of neuroendocrinology 16 (4), 340-347, 2004
Copper-mediated amyloid-β toxicity is associated with an intermolecular histidine bridge
DP Smith, DG Smith, CC Curtain, JF Boas, JR Pilbrow, GD Ciccotosto, ...
Journal of Biological Chemistry 281 (22), 15145-15154, 2006
Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones
L Deng, C De la Fuente, P Fu, L Wang, R Donnelly, JD Wade, P Lambert, ...
Virology 277 (2), 278-295, 2000
Current challenges in peptide-based drug discovery
L Otvos Jr, JD Wade
Frontiers in Chemistry 2, 62, 2014
DBU as an N alpha-deprotecting reagent for the fluorenylmethoxycarbonyl group in continuous flow solid-phase peptide synthesis.
JD Wade, J Bedford, RC Sheppard, GW Tregear
Peptide research 4 (3), 194-199, 1991
Alzheimer disease β-amyloid activity mimics cholesterol oxidase
L Puglielli, AL Friedlich, KDR Setchell, S Nagano, C Opazo, RA Cherny, ...
The Journal of clinical investigation 115 (9), 2556-2563, 2005
Peptide thioester preparation by Fmoc solid phase peptide synthesis for use in native chemical ligation
AB Clippingdale, CJ Barrow, JD Wade
Journal of peptide science: an official publication of the European Peptide …, 2000
Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo
RAD Bathgate, F Lin, NF Hanson, L Otvos, A Guidolin, C Giannakis, ...
Biochemistry 45 (3), 1043-1053, 2006
The amyloid‐β peptide and its role in Alzheimer's disease
AB Clippingdale, JD Wade, CJ Barrow
Journal of peptide science: an official publication of the European Peptide …, 2001
Design and development of a peptide-based adiponectin receptor agonist for cancer treatment
L Otvos, E Haspinger, F La Russa, F Maspero, P Graziano, I Kovalszky, ...
BMC biotechnology 11 (1), 90, 2011
Methylation of the imidazole side chains of the Alzheimer disease amyloid-β peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity
AK Tickler, DG Smith, GD Ciccotosto, DJ Tew, CC Curtain, D Carrington, ...
Journal of Biological Chemistry 280 (14), 13355-13363, 2005
R3 (BΔ23–27) R/I5 Chimeric Peptide, a Selective Antagonist for GPCR135 and GPCR142 over Relaxin Receptor LGR7 IN VITRO AND IN VIVO CHARACTERIZATION
C Kuei, S Sutton, P Bonaventure, C Pudiak, J Shelton, J Zhu, ...
Journal of Biological Chemistry 282 (35), 25425-25435, 2007
Amphipathic α-helical peptide, HP (2–20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions
SC Park, MH Kim, MA Hossain, SY Shin, Y Kim, L Stella, JD Wade, Y Park, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1778 (1), 229-241, 2008
Physiological and pathophysiological influences on thirst
MJ McKinley, MJ Cairns, DA Denton, G Egan, ML Mathai, A Uschakov, ...
Physiology & behavior 81 (5), 795-803, 2004
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