| Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis SE Garnish, Y Meng, A Koide, JJ Sandow, E Denbaum, AV Jacobsen, ... Nature communications 12 (1), 2211, 2021 | 67 | 2021 |
| Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis Y Meng, KA Davies, C Fitzgibbon, SN Young, SE Garnish, CR Horne, ... Nature Communications 12 (1), 6783, 2021 | 59 | 2021 |
| A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells AL Samson, C Fitzgibbon, KM Patel, JM Hildebrand, LW Whitehead, ... Cell Death & Differentiation 28 (7), 2126-2144, 2021 | 47 | 2021 |
| “Just a spoonful of sugar...”: import of sialic acid across bacterial cell membranes RA North, CR Horne, JS Davies, DM Remus, AC Muscroft-Taylor, P Goyal, ... Biophysical Reviews 10, 219-227, 2018 | 40 | 2018 |
| Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL A Sethi, CR Horne, C Fitzgibbon, K Wilde, KA Davies, SE Garnish, ... Cell Death & Differentiation 29 (9), 1804-1815, 2022 | 26 | 2022 |
| The web of death: the expanding complexity of necroptotic signaling CR Horne, AL Samson, JM Murphy Trends in Cell Biology 33 (2), 162-174, 2023 | 25 | 2023 |
| Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism CR Horne, H Venugopal, S Panjikar, DM Wood, A Henrickson, E Brookes, ... Nature communications 12 (1), 1988, 2021 | 22 | 2021 |
| Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus JS Davies, D Coombes, CR Horne, FG Pearce, R Friemann, RA North, ... FEBS letters 593 (1), 52-66, 2019 | 20 | 2019 |
| Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker BC Lechtenberg, MP Gehring, TP Light, CR Horne, MW Matsumoto, ... Nature communications 12 (1), 7047, 2021 | 18 | 2021 |
| On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism CR Horne, L Kind, JS Davies, RCJ Dobson Proteins: Structure, Function, and Bioinformatics 88 (5), 654-668, 2020 | 16 | 2020 |
| Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2 AV Peskin, FC Meotti, KM Kean, C Göbl, AS Peixoto, PE Pace, CR Horne, ... Journal of Biological Chemistry 296, 2021 | 15 | 2021 |
| The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus D Coombes, JS Davies, MC Newton-Vesty, CR Horne, TG Setty, ... Journal of Biological Chemistry 295 (10), 3301-3315, 2020 | 15 | 2020 |
| The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs LY Liang, M Roy, CR Horne, JJ Sandow, M Surudoi, LF Dagley, ... Biochemical Journal 478 (17), 3351-3371, 2021 | 14 | 2021 |
| Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling Y Meng, CR Horne, AL Samson, LF Dagley, SN Young, JJ Sandow, ... Cell Death & Disease 13 (6), 565, 2022 | 13 | 2022 |
| Multi-wavelength analytical ultracentrifugation as a tool to characterise protein–DNA interactions in solution CR Horne, A Henrickson, B Demeler, RCJ Dobson European Biophysics Journal 49 (8), 819-827, 2020 | 13 | 2020 |
| Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL T Sadras, FB Jalud, HJ Kosasih, CR Horne, LM Brown, S El-Kamand, ... Leukemia 37 (4), 905-909, 2023 | 7 | 2023 |
| Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix MR Oliver, CR Horne, S Shrestha, JR Keown, LY Liang, SN Young, ... Nature Communications 12 (1), 1002, 2021 | 7 | 2021 |
| Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation DM Wood, RCJ Dobson, CR Horne Biochemical Society Transactions 49 (6), 2711-2726, 2021 | 6 | 2021 |
| N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization MJ Currie, L Manjunath, CR Horne, PM Rendle, R Subramanian, ... Journal of Biological Chemistry 297 (4), 2021 | 6 | 2021 |
| A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation SE Garnish, KR Martin, M Kauppi, VE Jackson, R Ambrose, VV Eng, ... Nature Communications 14 (1), 6046, 2023 | 5 | 2023 |
James M. MurphyHead of Inflammation Division, Walter and Eliza Hall Institute of Medical ResearchVerified email at wehi.edu.au
