| Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells A Le, AN Lane, M Hamaker, S Bose, A Gouw, J Barbi, T Tsukamoto, ... Cell metabolism 15 (1), 110-121, 2012 | 1165 | 2012 |
| Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1 MJ Seltzer, BD Bennett, AD Joshi, P Gao, AG Thomas, DV Ferraris, ... Cancer research 70 (22), 8981-8987, 2010 | 581 | 2010 |
| Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1, 2, 4-thiadiazol-2-yl) ethyl sulfide (BPTES) MM Robinson, SJ Mcbryant, T Tsukamoto, C Rojas, DV Ferraris, ... Biochemical Journal 406 (3), 407-414, 2007 | 364 | 2007 |
| Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic … SY Cho, KL Gage, RC Mease, S Senthamizhchelvan, DP Holt, ... Journal of Nuclear Medicine 53 (12), 1883-1891, 2012 | 329 | 2012 |
| Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor C Rojas, M Stathis, AG Thomas, EB Massuda, J Alt, J Zhang, ... Anesthesia & Analgesia 107 (2), 469-478, 2008 | 285 | 2008 |
| Glutamate carboxypeptidase II in diagnosis and treatment of neurologic disorders and prostate cancer C Barinka, C Rojas, B Slusher, M Pomper Current medicinal chemistry 19 (6), 856-870, 2012 | 241 | 2012 |
| Palonosetron triggers 5-HT3 receptor internalization and causes prolonged inhibition of receptor function C Rojas, AG Thomas, J Alt, M Stathis, J Zhang, EB Rubenstein, ... European journal of pharmacology 626 (2-3), 193-199, 2010 | 231 | 2010 |
| Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1, 2, 4-thiadiazol-2-yl) ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors K Shukla, DV Ferraris, AG Thomas, M Stathis, B Duvall, G Delahanty, J Alt, ... Journal of medicinal chemistry 55 (23), 10551-10563, 2012 | 229 | 2012 |
| Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer A Elgogary, Q Xu, B Poore, J Alt, SC Zimmermann, L Zhao, J Fu, B Chen, ... Proceedings of the National Academy of Sciences 113 (36), E5328-E5336, 2016 | 216 | 2016 |
| Molecular mechanisms of 5-HT3 and NK1 receptor antagonists in prevention of emesis C Rojas, M Raje, T Tsukamoto, BS Slusher European journal of pharmacology 722, 26-37, 2014 | 175 | 2014 |
| Pharmacological mechanisms of 5-HT3 and tachykinin NK1 receptor antagonism to prevent chemotherapy-induced nausea and vomiting C Rojas, BS Slusher European journal of pharmacology 684 (1-3), 1-7, 2012 | 162 | 2012 |
| Synthesis and Biological Evaluation of d-Amino Acid Oxidase Inhibitors D Ferraris, B Duvall, YS Ko, AG Thomas, C Rojas, P Majer, K Hashimoto, ... Journal of medicinal chemistry 51 (12), 3357-3359, 2008 | 160 | 2008 |
| Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II C Barinka, M Rinnová, P Šácha, C Rojas, P Majer, BS Slusher, ... Journal of neurochemistry 80 (3), 477-487, 2002 | 156 | 2002 |
| Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor P Majer, PF Jackson, G Delahanty, BS Grella, YS Ko, W Li, Q Liu, ... Journal of medicinal chemistry 46 (10), 1989-1996, 2003 | 155 | 2003 |
| The antiemetic 5-HT3 receptor antagonist Palonosetron inhibits substance P-mediated responses in vitro and in vivo C Rojas, Y Li, J Zhang, M Stathis, J Alt, AG Thomas, S Cantoreggi, ... Journal of pharmacology and experimental therapeutics 335 (2), 362-368, 2010 | 151 | 2010 |
| Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models GD Ghadge, BS Slusher, A Bodner, MD Canto, K Wozniak, AG Thomas, ... Proceedings of the National Academy of Sciences 100 (16), 9554-9559, 2003 | 143 | 2003 |
| High-affinity near-infrared fluorescent small-molecule contrast agents for in vivo imaging of prostate-specific membrane antigen V Humblet, R Lapidus, LR Williams, T Tsukamoto, C Rojas, P Majer, B Hin, ... Molecular imaging 4 (4), 7290.2005. 05163, 2005 | 142 | 2005 |
| Synthesis and biological evaluation of low molecular weight fluorescent imaging agents for the prostate-specific membrane antigen Y Chen, M Pullambhatla, SR Banerjee, Y Byun, M Stathis, C Rojas, ... Bioconjugate chemistry 23 (12), 2377-2385, 2012 | 135 | 2012 |
| Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma R Rais, A Jancarik, L Tenora, M Nedelcovych, J Alt, J Englert, C Rojas, ... Journal of medicinal chemistry 59 (18), 8621-8633, 2016 | 115 | 2016 |
| Targeting the glutamatergic system for the treatment of HIV-associated neurocognitive disorders MC Potter, M Figuera-Losada, C Rojas, BS Slusher Journal of Neuroimmune Pharmacology 8, 594-607, 2013 | 115 | 2013 |
