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Aaron Fleming
Aaron Fleming
Research Scientist, University of Utah
Verified email at chem.utah.edu - Homepage
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Cited by
Year
Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair
AM Fleming, Y Ding, CJ Burrows
Proceedings of the National Academy of Sciences 114 (10), 2604-2609, 2017
3622017
Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution
V Khoddami, A Yerra, TL Mosbruger, AM Fleming, CJ Burrows, BR Cairns
Proceedings of the National Academy of Sciences 116 (14), 6784-6789, 2019
2132019
Sequencing the mouse genome for the oxidatively modified base 8-oxo-7, 8-dihydroguanine by OG-Seq
Y Ding, AM Fleming, CJ Burrows
Journal of the American Chemical Society 139 (7), 2569-2572, 2017
1672017
The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures
J Zhou, AM Fleming, AM Averill, CJ Burrows, SS Wallace
Nucleic acids research 43 (8), 4039-4054, 2015
1662015
G-quadruplex folds of the human telomere sequence alter the site reactivity and reaction pathway of guanine oxidation compared to duplex DNA
AM Fleming, CJ Burrows
Chemical research in toxicology 26 (4), 593-607, 2013
1542013
A role for the fifth G-track in G-quadruplex forming oncogene promoter sequences during oxidative stress: Do these “spare tires” have an evolved function?
AM Fleming, J Zhou, SS Wallace, CJ Burrows
ACS central science 1 (5), 226-233, 2015
1412015
8-Oxo-7, 8-dihydroguanine, friend and foe: Epigenetic-like regulator versus initiator of mutagenesis
AM Fleming, CJ Burrows
DNA repair 56, 75-83, 2017
1392017
Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context
J Zhou, M Liu, AM Fleming, CJ Burrows, SS Wallace
Journal of Biological Chemistry 288 (38), 27263-27272, 2013
1362013
Zika virus genomic RNA possesses conserved G-quadruplexes characteristic of the flaviviridae family
AM Fleming, Y Ding, A Alenko, CJ Burrows
ACS infectious diseases 2 (10), 674-681, 2016
1352016
Interplay of guanine oxidation and G-quadruplex folding in gene promoters
AM Fleming, CJ Burrows
Journal of the American Chemical Society 142 (3), 1115-1136, 2019
1252019
Nanopore detection of 8-oxo-7, 8-dihydro-2′-deoxyguanosine in immobilized single-stranded DNA via adduct formation to the DNA damage site
AEP Schibel, N An, Q Jin, AM Fleming, CJ Burrows, HS White
Journal of the American Chemical Society 132 (51), 17992-17995, 2010
1222010
4n–1 Is a “Sweet Spot” in DNA i-Motif Folding of 2′-Deoxycytidine Homopolymers
AM Fleming, Y Ding, RA Rogers, J Zhu, J Zhu, AD Burton, CB Carlisle, ...
Journal of the American Chemical Society 139 (13), 4682-4689, 2017
1192017
Formation and processing of DNA damage substrates for the hNEIL enzymes
AM Fleming, CJ Burrows
Free Radical Biology and Medicine 107, 35-52, 2017
1172017
Crown ether–electrolyte interactions permit nanopore detection of individual DNA abasic sites in single molecules
N An, AM Fleming, HS White, CJ Burrows
Proceedings of the National Academy of Sciences 109 (29), 11504-11509, 2012
1162012
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
Y Sejersted, GA Hildrestrand, D Kunke, V Rolseth, SZ Krokeide, ...
Proceedings of the National Academy of Sciences 108 (46), 18802-18807, 2011
1122011
Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin
SZ Krokeide, JK Laerdahl, M Salah, L Luna, FH Cederkvist, AM Fleming, ...
DNA repair 12 (12), 1159-1164, 2013
1092013
8-Oxo-7, 8-dihydroguanine in the context of a gene promoter G-quadruplex is an on–off switch for transcription
AM Fleming, J Zhu, Y Ding, CJ Burrows
ACS chemical biology 12 (9), 2417-2426, 2017
992017
Unzipping kinetics of duplex DNA containing oxidized lesions in an α-hemolysin nanopore
Q Jin, AM Fleming, CJ Burrows, HS White
Journal of the American Chemical Society 134 (26), 11006-11011, 2012
962012
Structural context effects in the oxidation of 8-oxo-7, 8-dihydro-2′-deoxyguanosine to hydantoin products: electrostatics, base stacking, and base pairing
AM Fleming, JG Muller, AC Dlouhy, CJ Burrows
Journal of the American Chemical Society 134 (36), 15091-15102, 2012
932012
Nanopore detection of 8-oxoguanine in the human telomere repeat sequence
N An, AM Fleming, HS White, CJ Burrows
ACS nano 9 (4), 4296-4307, 2015
922015
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