Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia CN Hahn, CE Chong, CL Carmichael, EJ Wilkins, PJ Brautigan, XC Li, ... Nature genetics 43 (10), 1012-1017, 2011 | 681 | 2011 |
Integrative analysis of RUNX1 downstream pathways and target genes J Michaud, KM Simpson, R Escher, K Buchet-Poyau, T Beissbarth, ... BMC genomics 9, 1-17, 2008 | 145 | 2008 |
Genomic subtyping and therapeutic targeting of acute erythroleukemia I Iacobucci, J Wen, M Meggendorfer, JK Choi, L Shi, SB Pounds, ... Nature genetics 51 (4), 694-704, 2019 | 116 | 2019 |
RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML AL Brown, P Arts, CL Carmichael, M Babic, J Dobbins, CE Chong, ... Blood advances 4 (6), 1131-1144, 2020 | 115 | 2020 |
Novel RUNX1 mutations in familial platelet disorder with enhanced risk for acute myeloid leukemia: clues for improved identification of the FPD/AML syndrome MCJ Jongmans, RP Kuiper, CL Carmichael, EJ Wilkins, N Dors, ... Leukemia 24 (1), 242-246, 2010 | 100 | 2010 |
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling S Goossens, E Radaelli, O Blanchet, K Durinck, J Van der Meulen, ... Nature communications 6 (1), 5794, 2015 | 88 | 2015 |
Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome AP Ng, CD Hyland, D Metcalf, CL Carmichael, SJ Loughran, L Di Rago, ... Blood, The Journal of the American Society of Hematology 115 (19), 3966-3969, 2010 | 77 | 2010 |
ETO2-GLIS2 hijacks transcriptional complexes to drive cellular identity and self-renewal in pediatric acute megakaryoblastic leukemia C Thirant, C Ignacimouttou, CK Lopez, L Le Mouël, C Thiollier, A Siret, ... Cancer cell 31 (3), 452-465, 2017 | 75 | 2017 |
Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing A Keniry, LJ Gearing, N Jansz, J Liu, AZ Holik, PF Hickey, SA Kinkel, ... Epigenetics & chromatin 9, 1-20, 2016 | 70 | 2016 |
Hematopoietic defects in the Ts1Cje mouse model of Down syndrome CL Carmichael, IJ Majewski, WS Alexander, D Metcalf, DJ Hilton, ... Blood, The Journal of the American Society of Hematology 113 (9), 1929-1937, 2009 | 61 | 2009 |
Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia CL Carmichael, D Metcalf, KJ Henley, EA Kruse, L Di Rago, S Mifsud, ... Proceedings of the National Academy of Sciences 109 (38), 15437-15442, 2012 | 51 | 2012 |
The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1 CL Carmichael, J Wang, T Nguyen, O Kolawole, A Benyoucef, ... Blood, The Journal of the American Society of Hematology 136 (8), 957-973, 2020 | 42 | 2020 |
Low-fouling and biodegradable protein-based particles for thrombus imaging T Bonnard, A Jayapadman, JA Putri, J Cui, Y Ju, C Carmichael, ... ACS nano 12 (7), 6988-6996, 2018 | 35 | 2018 |
Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice M Takiguchi, LE Dow, JE Prier, CL Carmichael, BT Kile, SJ Turner, ... PloS one 8 (1), e54009, 2013 | 34 | 2013 |
Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers A Fagnan, FO Bagger, MR Piqué-Borràs, C Ignacimouttou, A Caulier, ... Blood, The Journal of the American Society of Hematology 136 (6), 698-714, 2020 | 32 | 2020 |
Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia S Goossens, S Peirs, W Van Loocke, J Wang, M Takawy, F Matthijssens, ... Blood, The Journal of the American Society of Hematology 129 (8), 981-990, 2017 | 25 | 2017 |
Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia JZ Tang, CL Carmichael, W Shi, D Metcalf, AP Ng, CD Hyland, ... Proceedings of the National Academy of Sciences 110 (15), 6091-6096, 2013 | 23 | 2013 |
Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity J Wang, C Farkas, A Benyoucef, C Carmichael, K Haigh, N Wong, ... PLoS biology 19 (9), e3001394, 2021 | 22 | 2021 |
GATA2 is a new predisposition gene for familial myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) HS Scott, CN Hahn, CL Carmichael, EJ Wilkins, CE Chong, PJ Brautigan, ... Blood 116 (21), LBA-3, 2010 | 21 | 2010 |
Poor prognosis in familial acute myeloid leukaemia with combined biallelic CEBPA mutations and downstream events affecting the ATM, FLT3 and CDX2 genes CL Carmichael, EJ Wilkins, H Bengtsson, MS Horwitz, TP Speed, ... British journal of haematology 150 (3), 382, 2010 | 18 | 2010 |