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Arun Parupudi
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Mechanism of reversible self-association of a monoclonal antibody: role of electrostatic and hydrophobic interactions
R Esfandiary, A Parupudi, J Casas-Finet, D Gadre, H Sathish
Journal of pharmaceutical sciences 104 (2), 577-586, 2015
1102015
A systematic multitechnique approach for detection and characterization of reversible self-association during formulation development of therapeutic antibodies
R Esfandiary, DB Hayes, A Parupudi, J Casas-Finet, S Bai, HS Samra, ...
Journal of pharmaceutical sciences 102 (9), 3089-3099, 2013
632013
Effects of salt-induced reversible self-association on the elution behavior of a monoclonal antibody in cation exchange chromatography
H Luo, N Macapagal, K Newell, A Man, A Parupudi, Y Li, Y Li
Journal of Chromatography A 1362, 186-193, 2014
572014
High-throughput self-interaction chromatography: applications in protein formulation prediction
DH Johnson, A Parupudi, WW Wilson, LJ DeLucas
Pharmaceutical research 26, 296-305, 2009
432009
Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions
PS Sarangapani, J Weaver, A Parupudi, TMD Besong, GG Adams, ...
Journal of pharmaceutical sciences 105 (12), 3496-3506, 2016
272016
Determination of interaction parameters for reversibly self-associating antibodies: a comparative analysis
MM Hopkins, CL Lambert, JS Bee, A Parupudi, DL Bain
Journal of Pharmaceutical Sciences 107 (7), 1820-1830, 2018
182018
Electrostatically driven protein–protein interactions: quantitative prediction of second osmotic virial coefficients to aid antibody design
H Shahfar, Q Du, A Parupudi, L Shan, R Esfandiary, CJ Roberts
The Journal of Physical Chemistry Letters 13 (5), 1366-1372, 2022
152022
Practical considerations for detection and characterization of sub-micron particles in protein solutions by nanoparticle tracking analysis
F Gruia, A Parupudi, A Polozova
PDA Journal of Pharmaceutical Science and Technology 69 (3), 427-439, 2015
152015
Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions
SK Chaturvedi, A Parupudi, K Juul-Madsen, A Nguyen, T Vorup-Jensen, ...
MAbs 12 (1), 1810488, 2020
132020
Biophysical characterization of influenza A virions
A Parupudi, F Gruia, SA Korman, S Dragulin-Otto, K Sra, RL Remmele Jr, ...
Journal of Virological Methods 247, 91-98, 2017
92017
Monoclonal antibody based in vitro potency assay as a predictor of antigenic integrity and in vivo immunogenicity of a Respiratory Syncytial Virus post-fusion F-protein based …
MD Djagbare, L Yu, A Parupudi, J Sun, ML Coughlin, BS Rush, G Sanyal
Vaccine 36 (12), 1673-1680, 2018
82018
Global multi-method analysis of interaction parameters for reversibly self-associating macromolecules at high concentrations
A Parupudi, SK Chaturvedi, R Adão, RW Harkness, S Dragulin-Otto, ...
Scientific Reports 11 (1), 5741, 2021
62021
Deamidation in moxetumomab pasudotox leading to conformational change and immunotoxin activity loss
X Lu, S Lin, N De Mel, A Parupudi, J Delmar, M Pandey, X Wang, J Wang
Journal of Pharmaceutical Sciences 109 (9), 2676-2683, 2020
52020
Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies
A Dippel, A Gallegos, V Aleti, A Barnes, X Chen, E Christian, J Delmar, ...
Mabs 15 (1), 2152526, 2023
42023
Impact of mutations on the higher order structure and activity of a recombinant uricase
F Gruia, A Parupudi, M Baca, C Ward, A Nyborg, RL Remmele Jr, JS Bee
Journal of Pharmaceutical Sciences 106 (4), 1018-1024, 2017
42017
Energetic dissection of Mab-specific reversible self-association reveals unique thermodynamic signatures
MM Hopkins, A Parupudi, JS Bee, DL Bain
Pharmaceutical Research 38, 243-255, 2021
32021
Comparative thermodynamics of the reversible self-association of therapeutic mAbs reveal opposing roles for linked proton-and ion-binding events
MM Hopkins, IH Antonopoulos, A Parupudi, JS Bee, DL Bain
Pharmaceutical Research 40 (6), 1383-1397, 2023
12023
Formulations of anti-il-33 antibodies
S Ekizoglou, MSM Ahmed, R Esfandiary, A Parupudi
US Patent App. 17/998,388, 2023
2023
Formulation of Bispecific Antibodies
A Parupudi
WO Patent 2016036678A1, 2016
2016
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Articles 1–19