Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity D Chessman, L Kostenko, T Lethborg, AW Purcell, NA Williamson, ... Immunity 28 (6), 822-832, 2008 | 372 | 2008 |
T cell allorecognition via molecular mimicry WA Macdonald, Z Chen, S Gras, JK Archbold, FE Tynan, CS Clements, ... Immunity 31 (6), 897-908, 2009 | 296 | 2009 |
A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition WA Macdonald, AW Purcell, NA Mifsud, LK Ely, DS Williams, L Chang, ... The Journal of experimental medicine 198 (5), 679-691, 2003 | 229 | 2003 |
The CDR3 regions of an immunodominant T cell receptor dictate the'energetic landscape'of peptide-MHC recognition NA Borg, LK Ely, T Beddoe, WA Macdonald, HH Reid, CS Clements, ... Nature immunology 6 (2), 171-180, 2005 | 205 | 2005 |
Crossreactive T cells spotlight the germline rules for αβ T cell-receptor interactions with MHC molecules S Dai, ES Huseby, K Rubtsova, J Scott-Browne, F Crawford, ... Immunity 28 (3), 324-334, 2008 | 195 | 2008 |
Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion D Zernich, AW Purcell, WA Macdonald, L Kjer-Nielsen, LK Ely, N Laham, ... The Journal of experimental medicine 200 (1), 13-24, 2004 | 184 | 2004 |
Antigen ligation triggers a conformational change within the constant domain of the αβ T cell receptor T Beddoe, Z Chen, CS Clements, LK Ely, SR Bushell, JP Vivian, ... Immunity 30 (6), 777-788, 2009 | 144 | 2009 |
Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition JK Archbold, WA Macdonald, S Gras, LK Ely, JJ Miles, MJ Bell, ... Journal of Experimental Medicine 206 (1), 209-219, 2009 | 113 | 2009 |
Dissecting the role of peptides in the immune response: theory, practice and the application to vaccine design AW Purcell, W Zeng, NA Mifsud, LK Ely, WA Macdonald, DC Jackson Journal of Peptide Science: An Official Publication of the European Peptide …, 2003 | 74 | 2003 |
Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry JK Archbold, WA Macdonald, JJ Miles, RM Brennan, L Kjer-Nielsen, ... Journal of biological chemistry 281 (45), 34324-34332, 2006 | 73 | 2006 |
T-cell allorecognition: a case of mistaken identity or déjà vu? JK Archbold, WA Macdonald, SR Burrows, J Rossjohn, J McCluskey Trends in immunology 29 (5), 220-226, 2008 | 66 | 2008 |
T cell allorecognition and MHC restriction—A case of Jekyll and Hyde? JK Archbold, LK Ely, L Kjer-Nielsen, SR Burrows, J Rossjohn, ... Molecular immunology 45 (3), 583-598, 2008 | 66 | 2008 |
The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state CS Clements, L Kjer-Nielsen, WA MacDonald, AG Brooks, AW Purcell, ... Acta Crystallographica Section D: Biological Crystallography 58 (12), 2131-2134, 2002 | 65 | 2002 |
Specificity on a knife-edge: the αβ T cell receptor CS Clements, MA Dunstone, WA Macdonald, J McCluskey, J Rossjohn Current opinion in structural biology 16 (6), 787-795, 2006 | 46 | 2006 |
Identification of a dominant self‐ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex W Macdonald, DS Williams, CS Clements, JJ Gorman, L Kjer-Nielsen, ... FEBS letters 527 (1-3), 27-32, 2002 | 42 | 2002 |
HLA molecules of the major histocompatibility complex J McCluskey, S Gras, M Bharadwaj, L Kjer-Nielsen, WA Macdonald, ... The HLA Complex in Biology and Medicine: A Resource Book, 86-118, 2010 | 4 | 2010 |
Impact of natural HLA class I polymorphism and the pathway of antigen presentation D Zernich, AW Purcell, WA Macdonald, L Kjer-Nielsen, LK Ely, N Laham, ... GENES AND IMMUNITY 5, S63-S63, 2004 | 1 | 2004 |
Antigen ligation triggers a conformational change within the constant domain of the alpha/beta T-cell receptor J McCluskey, T Beddoe, CS Clements, Z Chen, LK Ely, SR Bushell, ... TISSUE ANTIGENS 71 (4), 284-284, 2008 | | 2008 |
The crystal structure of HLA-B* 5701: Implications for abacavir hypersensitivity JK Archbold, WA Macdonald, AW Purcell, D Chessman, J McCluskey, ... TISSUE ANTIGENS 66 (5), 351-352, 2005 | | 2005 |
The CDR3 regions of an immunodominant T cell receptor dictate the'energetic landscape'of peptide-MHC recognition T Beddoe, N Borg, L Ely, W Macdonald, H Reid, C Clements, A Purcell, ... FEBS JOURNAL 272, 400-400, 2005 | | 2005 |