|Engineering a humanized bone organ model in mice to study bone metastases|
LC Martine, BM Holzapfel, JA McGovern, F Wagner, VM Quent, P Hesami, ...
Nature protocols 12 (4), 639, 2017
|Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality|
BWC Tse, M Volpert, E Ratther, N Stylianou, M Nouri, K McGowan, ...
Oncogene 36 (24), 3417-3427, 2017
|Animal models for bone tissue engineering and modelling disease|
JA McGovern, M Griffin, DW Hutmacher
Disease models & mechanisms 11 (4), dmm033084, 2018
|Rational design of mouse models for cancer research|
M Landgraf, JA McGovern, P Friedl, DW Hutmacher
Trends in biotechnology 36 (3), 242-251, 2018
|Quantitative comparison of the spreading and invasion of radial growth phase and metastatic melanoma cells in a three-dimensional human skin equivalent model|
P Haridas, JA McGovern, SDL McElwain, MJ Simpson
PeerJ 5, e3754, 2017
|Quantifying rates of cell migration and cell proliferation in co-culture barrier assays reveals how skin and melanoma cells interact during melanoma spreading and invasion|
P Haridas, CJ Penington, JA McGovern, DLS McElwain, MJ Simpson
Journal of theoretical biology 423, 13-25, 2017
|The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome|
EJ Crosbie, NAJ Ryan, MJ Arends, T Bosse, J Burn, JM Cornes, ...
Genetics in Medicine, 1-11, 2019
|Severe hypoxia and malnutrition collectively contribute to scar fibroblast inhibition and cell apoptosis|
EC Lynam, Y Xie, R Dawson, J Mcgovern, Z Upton, XQ Wang
Wound Repair and Regeneration 23 (5), 664-671, 2015
|Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study|
A Shafiee, JA McGovern, CA Lahr, C Meinert, D Moi, F Wagner, ...
International journal of cancer 143 (6), 1470-1482, 2018
|Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma|
F Wagner, BM Holzapfel, JA McGovern, A Shafiee, JG Baldwin, ...
Biomaterials 171, 230-246, 2018
|Stratum basale keratinocyte expression of the cell‐surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration|
JA McGovern, JR Heinemann, LJ Burke, R Dawson, TJ Parker, Z Upton, ...
British Journal of Dermatology 168 (3), 496-503, 2013
|Attenuated kallikrein‐related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models|
JA McGovern, C Meinert, SJ de Veer, BG Hollier, TJ Parker, Z Upton
British Journal of Dermatology 176 (1), 145-158, 2017
|Standard melanoma-associated markers do not identify the MM127 metastatic melanoma cell line|
P Haridas, JA McGovern, AS Kashyap, DLS McElwain, MJ Simpson
Scientific reports 6 (1), 1-6, 2016
|Humanization of the prostate microenvironment reduces homing of PC3 prostate cancer cells to human tissue-engineered bone|
JA McGovern, A Shafiee, F Wagner, CA Lahr, M Landgraf, C Meinert, ...
Cancers 10 (11), 438, 2018
|Targeting insulin-like growth factor-I and extracellular matrix interactions in melanoma progression|
B Murekatete, A Shokoohmand, J McGovern, L Mohanty, C Meinert, ...
Scientific reports 8 (1), 1-12, 2018
|Provisional matrix deposition in hemostasis and venous insufficiency: tissue preconditioning for nonhealing venous ulcers|
TJ Parker, JA Broadbent, JA McGovern, DA Broszczak, CN Parker, ...
Advances in wound care 4 (3), 174-191, 2015
|Menstrual fluid factors facilitate tissue repair: identification and functional action in endometrial and skin repair|
J Evans, G Infusini, J McGovern, L Cuttle, A Webb, T Nebl, L Milla, ...
The FASEB Journal 33 (1), 584-605, 2019
|Three-dimensional experiments and individual based simulations show that cell proliferation drives melanoma nest formation in human skin tissue|
P Haridas, AP Browning, JA McGovern, DLS McElwain, MJ Simpson
BMC systems biology 12 (1), 34, 2018
|Antagonists of IGF: vitronectin interactions inhibit IGF-I–induced breast cancer cell functions|
AS Kashyap, GK Shooter, A Shokoohmand, J McGovern, ...
Molecular cancer therapeutics 15 (7), 1602-1613, 2016
|A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma|
F Wagner, BM Holzapfel, LC Martine, J McGovern, CA Lahr, M Boxberg, ...
Acta biomaterialia 89, 372-381, 2019