Stefan Mann
Stefan Mann
GAMS Development Corp
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hERG K+ channels: structure, function, and clinical significance
JI Vandenberg, MD Perry, MJ Perrin, SA Mann, Y Ke, AP Hill
Physiological reviews, 2012
R222Q SCN5A Mutation Is Associated With Reversible Ventricular Ectopy and Dilated Cardiomyopathy
SA Mann, ML Castro, M Ohanian, G Guo, P Zodgekar, A Sheu, ...
Journal of the American College of Cardiology 60 (16), 1566-1573, 2012
Monitoring cell movements and volume changes with pulse‐mode scanning ion conductance microscopy
P Happel, G Hoffmann, SA Mann, ID Dietzel
Journal of microscopy 212 (2), 144-151, 2003
Pulse-mode scanning ion conductance microscopy—a method to investigate cultured hippocampal cells
SA Mann, G Hoffmann, A Hengstenberg, W Schuhmann, ID Dietzel
Journal of neuroscience methods 116 (2), 113-117, 2002
Epistatic effects of potassium channel variation on cardiac repolarization and atrial fibrillation risk
SA Mann, R Otway, G Guo, M Soka, L Karlsdotter, G Trivedi, M Ohanian, ...
Journal of the American College of Cardiology 59 (11), 1017-1025, 2012
Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis
B Liang, M Soka, AH Christensen, MS Olesen, AP Larsen, FK Knop, ...
Journal of Molecular and Cellular Cardiology 67, 69-76, 2014
Constant-distance mode scanning potentiometry. 1. Visualization of calcium carbonate dissolution in aqueous solution
M Etienne, A Schulte, S Mann, G Jordan, ID Dietzel, W Schuhmann
Analytical chemistry 76 (13), 3682-3688, 2004
Mapping the sequence of conformational changes underlying selectivity filter gating in the Kv11.1 potassium channel
DT Wang, AP Hill, SA Mann, PS Tan, JI Vandenberg
Nature structural & molecular biology 18 (1), 35-41, 2011
Natural products modulating the hERG channel: heartaches and hope
JM Kratz, U Grienke, O Scheel, SA Mann, JM Rollinger
Natural product reports 34 (8), 957-980, 2017
A transgenic zebrafish model of a human cardiac sodium channel mutation exhibits bradycardia, conduction-system abnormalities and early death
IG Huttner, G Trivedi, A Jacoby, SA Mann, JI Vandenberg, D Fatkin
Journal of molecular and cellular cardiology 61, 123-132, 2013
Corticosteroids reverse cytokine-induced block of survival and differentiation of oligodendrocyte progenitor cells from rats
SA Mann, B Versmold, R Marx, S Stahlhofen, ID Dietzel, R Heumann, ...
Journal of Neuroinflammation 5, 1-17, 2008
Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2
A Sadrieh, L Domanski, J Pitt-Francis, SA Mann, EC Hodkinson, CA Ng, ...
Nature communications 5 (1), 5069, 2014
Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain–domain interactions
Y Ke, CA Ng, MJ Hunter, SA Mann, J Heide, AP Hill, JI Vandenberg
Biochemical Journal 454 (1), 69-77, 2013
Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes
SA Mann, M Imtiaz, A Winbo, A Rydberg, MD Perry, JP Couderc, ...
Journal of molecular and cellular cardiology 100, 25-34, 2016
Getting to the heart of hERG K+ channel gating
MD Perry, CA Ng, SA Mann, A Sadrieh, M Imtiaz, AP Hill, JI Vandenberg
The Journal of physiology 593 (12), 2575-2585, 2015
Rescue of protein expression defects may not be enough to abolish the pro‐arrhythmic phenotype of long QT type 2 mutations
MD Perry, CA Ng, K Phan, E David, K Steer, MJ Hunter, SA Mann, ...
The Journal of physiology 594 (14), 4031-4049, 2016
In silico assessment of kinetics and state dependent binding properties of drugs causing acquired LQTS
W Lee, SA Mann, MJ Windley, MS Imtiaz, JI Vandenberg, AP Hill
Progress in biophysics and molecular biology 120 (1-3), 89-99, 2016
Kinetics of drug interaction with the Kv11. 1 potassium channel
AP Hill, MJ Perrin, J Heide, TJ Campbell, SA Mann, JI Vandenberg
Molecular pharmacology 85 (5), 769-776, 2014
The schizophrenia-associated Kv11. 1-3.1 isoform results in reduced current accumulation during repetitive brief depolarizations
J Heide, SA Mann, JI Vandenberg
Public Library of Science 7 (9), e45624, 2012
Evolution of mathematical models of cardiomyocyte electrophysiology
B Amuzescu, R Airini, FB Epureanu, SA Mann, T Knott, BM Radu
Mathematical Biosciences 334, 108567, 2021
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