Jan Claesen
Jan Claesen
Assistant Professor, Lerner Research Institute, Cleveland Clinic
Verified email at ccf.org - Homepage
Cited by
Cited by
Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters
P Cimermancic, MH Medema, J Claesen, K Kurita, LCW Brown, ...
Cell 158 (2), 412-421, 2014
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
Synthetic biology to access and expand nature's chemical diversity
MJ Smanski, H Zhou, J Claesen, B Shen, MA Fischbach, CA Voigt
Nature Reviews Microbiology 14 (3), 135-149, 2016
Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights
Y Goto, B Li, J Claesen, Y Shi, MJ Bibb, WA van der Donk
PLoS biology 8 (3), e1000339, 2010
Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides
J Claesen, M Bibb
Proceedings of the National Academy of Sciences 107 (37), 16297-16302, 2010
Synthetic microbes as drug delivery systems
J Claesen, MA Fischbach
ACS synthetic biology 4 (4), 358-364, 2015
Contextual control of skin immunity and inflammation by Corynebacterium
VK Ridaura, N Bouladoux, J Claesen, YE Chen, AL Byrd, ...
Journal of Experimental Medicine 215 (3), 785-799, 2018
Propionibacterium-Produced Coproporphyrin III Induces Staphylococcus aureus Aggregation and Biofilm Formation
MS Wollenberg, J Claesen, IF Escapa, KL Aldridge, MA Fischbach, ...
MBio 5 (4), e01286-14, 2014
Biosynthesis and regulation of grisemycin, a new member of the linaridin family of ribosomally synthesized peptides produced by Streptomyces griseus IFO 13350
J Claesen, MJ Bibb
Journal of bacteriology 193 (10), 2510-2516, 2011
Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut
A Bell, J Brunt, E Crost, L Vaux, R Nepravishta, CD Owen, D Latousakis, ...
Nature microbiology 4 (12), 2393-2404, 2019
A Streptomyces coelicolor host for the heterologous expression of Type III polyketide synthase genes
A Thanapipatsiri, J Claesen, JP Gomez-Escribano, M Bibb, ...
Microbial cell factories 14 (1), 1-11, 2015
A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles
J Claesen, JB Spagnolo, SF Ramos, KL Kurita, AL Byrd, AA Aksenov, ...
Science Translational Medicine 12 (570), 2020
Gut symbionts Lactobacillus reuteri R2lc and 2010 encode a polyketide synthase cluster that activates the mammalian aryl hydrocarbon receptor
M zam, R Tocmo, JH Oh, A Afrazi, JD Mezrich, S Roos, J Claesen, ...
Applied and environmental microbiology 85 (10), e01661-18, 2019
Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation
I Johnston, LJ Osborn, RL Markley, EA McManus, A Kadam, KB Schultz, ...
bioRxiv, 2020.04. 22.055939, 2021
Topical antiseptics and the skin microbiota
J Claesen
Journal of Investigative Dermatology 138 (10), 2106-2107, 2018
Microbial Flavonoid Metabolism: A Cardiometabolic Disease Perspective
LJ Osborn, J Claesen, JM Brown
Annual Review of Nutrition 41, 433-454, 2021
A surgical method for continuous intraportal infusion of gut microbial metabolites in mice
D Orabi, LJ Osborn, K Fung, W Massey, AJ Horak, F Aucejo, I Choucair, ...
JCI insight 6 (9), 2021
Disruption of the gut microbiota attenuates epithelial ovarian cancer sensitivity to cisplatin therapy
L Chambers, EL Esakov, C Braley, L Trestan, Z Alali, D Bayik, J Lathia, ...
bioRxiv, 2020
Cloning and analysis of the cypemycin biosynthetic gene cluster
J Claesen
University of East Anglia, 2010
A Single Human-Relevant Fast Food Meal Rapidly Reorganizes Metabolomic and Transcriptomic Signatures in a Gut Microbiota-Dependent Manner
LJ Osborn, D Orabi, M Goudzari, N Sangwan, R Banerjee, AL Brown, ...
Immunometabolism 3 (3), 2021
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