| Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic YB Lee, HJ Chen, JN Peres, J Gomez-Deza, J Attig, M Štalekar, ... Cell reports 5 (5), 1178-1186, 2013 | 545 | 2013 |
| Deep homology of arthropod central complex and vertebrate basal ganglia NJ Strausfeld, F Hirth Science 340 (6129), 157-161, 2013 | 371 | 2013 |
| Mechanisms of α-synuclein induced synaptopathy in Parkinson's disease JC Bridi, F Hirth Frontiers in neuroscience 12, 338212, 2018 | 329 | 2018 |
| The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila B Bello, H Reichert, F Hirth Oxford University Press for The Company of Biologists Limited 133 (14), 2639 …, 2006 | 315 | 2006 |
| Drosophila melanogaster in the study of human neurodegeneration F Hirth CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2010 | 274 | 2010 |
| Developmental defects in brain segmentation caused by mutations of the homeobox genes orthodenticle and empty spiracles in Drosophila F Hirth, S Therianos, T Loop, WJ Gehring, H Reichert, ... Neuron 15 (4), 769-778, 1995 | 222 | 1995 |
| An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila F Hirth, L Kammermeier, E Frei, U Walldorf, M Noll, H Reichert Oxford University Press for The Company of Biologists Limited 130 (11), 2365 …, 2003 | 210 | 2003 |
| A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis BC Bello, F Hirth, AP Gould Neuron 37 (2), 209-219, 2003 | 210 | 2003 |
| Conserved genetic programs in insect and mammalian brain development F Hirth, H Reichert BioEssays 21 (8), 677-684, 1999 | 159 | 1999 |
| Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes DC Diaper, Y Adachi, B Sutcliffe, DM Humphrey, CJH Elliott, A Stepto, ... Human molecular genetics 22 (8), 1539-1557, 2013 | 154 | 2013 |
| The dopaminergic system in the aging brain of Drosophila KE White, DM Humphrey, F Hirth Frontiers in neuroscience 4, 7809, 2010 | 154 | 2010 |
| Homeotic gene action in embryonic brain development of Drosophila F Hirth, B Hartmann, H Reichert Development 125 (9), 1579-1589, 1998 | 136 | 1998 |
| Equivalence of the fly orthodenticle gene and the human OTX genes in embryonic brain development of Drosophila S Leuzinger, F Hirth, D Gerlich, D Acampora, A Simeone, WJ Gehring, ... Development 125 (9), 1703-1710, 1998 | 127 | 1998 |
| Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation P Tziortzouda, L Van Den Bosch, F Hirth Nature Reviews Neuroscience 22 (4), 197-208, 2021 | 125 | 2021 |
| Embryonic development of the Drosophila brain: formation of commissural and descending pathways S Therianos, S Leuzinger, F Hirth, CS Goodman, H Reichert Development 121 (11), 3849-3860, 1995 | 101 | 1995 |
| Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD DC Diaper, Y Adachi, L Lazarou, M Greenstein, FA Simoes, ... Human molecular genetics 22 (19), 3883-3893, 2013 | 93 | 2013 |
| A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration DA Solomon, A Stepto, WH Au, Y Adachi, DC Diaper, R Hall, A Rekhi, ... Brain 141 (10), 2908-2924, 2018 | 92 | 2018 |
| C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity YB Lee, P Baskaran, J Gomez-Deza, HJ Chen, AL Nishimura, BN Smith, ... Human molecular genetics 26 (24), 4765-4777, 2017 | 89 | 2017 |
| TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila LV Broeck, M Naval-Sanchez, Y Adachi, D Diaper, P Dourlen, J Chapuis, ... Cell reports 3 (1), 160-172, 2013 | 84 | 2013 |
| Differential expression and function of the Drosophila Pax6 genes eyeless and twin of eyeless in embryonic central nervous system development L Kammermeier, R Leemans, F Hirth, S Flister, U Wenger, U Walldorf, ... Mechanisms of development 103 (1-2), 71-78, 2001 | 80 | 2001 |
Christopher E ShawInstitute of Psychiatry, King's College LondonVerified email at kcl.ac.uk
