|The β-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation|
MD Castellone, V De Falco, DM Rao, R Bellelli, M Muthu, F Basolo, ...
Cancer research 69 (5), 1867-1876, 2009
|Ponatinib (AP24534) is a novel potent inhibitor of oncogenic RET mutants associated with thyroid cancer|
V De Falco, P Buonocore, M Muthu, L Torregrossa, F Basolo, M Billaud, ...
The Journal of Clinical Endocrinology & Metabolism 98 (5), E811-E819, 2013
|A novel de novo germ‐line V292M mutation in the extracellular region of RET in a patient with phaeochromocytoma and medullary thyroid carcinoma: functional …|
MD Castellone, A Verrienti, D Magendra Rao, M Sponziello, D Fabbro, ...
Clinical endocrinology 73 (4), 529-534, 2010
|Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis|
VT Cheriyan, Y Wang, M Muthu, S Jamal, D Chen, H Yang, LA Polin, ...
PloS one 9 (4), e93711, 2014
|CARP-1/CCAR1: a biphasic regulator of cancer cell growth and apoptosis|
M Muthu, VT Cheriyan, AK Rishi
Oncotarget 6 (9), 6499, 2015
|Identification and testing of novel CARP-1 functional mimetic compounds as inhibitors of non-small cell lung and triple negative breast cancers|
M Muthu, J Somagoni, VT Cheriyan, S Munie, E Levi, AE Ashour, ...
Journal of biomedical nanotechnology 11 (9), 1608-1627, 2015
|CARP-1 functional mimetics: A novel class of small molecule inhibitors of medulloblastoma cell growth|
AE Ashour, S Jamal, VT Cheryan, M Muthu, KMA Zoheir, AM Alafeefy, ...
PLoS One 8 (6), e66733, 2013
|CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells|
S Jamal, VT Cheriyan, M Muthu, S Munie, E Levi, AE Ashour, HI Pass, ...
PLoS One 9 (3), e89146, 2014
|A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma|
VT Cheriyan, HO Alsaab, S Sekhar, C Stieber, P Kesharwani, S Sau, ...
Oncotarget 8 (62), 104928, 2017
|CARP-1 functional mimetics are novel inhibitors of drug-resistant triple negative breast cancers|
RAK Cheriyan VT, Muthu M, Patel K, Sekhar S, Rajeswaran W, Larsen SD, Polin ...
|Mechanisms of neuroblastoma cell growth inhibition by CARP-1 functional mimetics|
M Muthu, VT Cheriyan, S Munie, E Levi, J Frank, AE Ashour, M Singh, ...
PLoS One 9 (7), e102567, 2014
|Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism—Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and …|
M Muthu, A Nordström
International journal of molecular sciences 20 (6), 1385, 2019
|A H2AX–CARP-1 Interaction Regulates Apoptosis Signaling Following DNA Damage|
SC Sekhar, J Venkatesh, VT Cheriyan, M Muthu, E Levi, H Assad, ...
Cancers 11 (2), 221, 2019
|A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers|
VT Cheriyan, H Alsaab, S Sekhar, J Venkatesh, A Mondal, I Vhora, S Sau, ...
Oncotarget 9 (51), 29680, 2018
|Antagonizing binding of cell cycle and apoptosis regulatory protein 1 (CARP-1) to the NEMO/IKKγ protein enhances the anticancer effect of chemotherapy|
J Venkatesh, SC Sekhar, VT Cheriyan, M Muthu, P Meister, E Levi, ...
Journal of Biological Chemistry 295 (11), 3532-3552, 2020
|GLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism|
M Muthu, R Kumar, AS Syed Khaja, JD Gilthorpe, JL Persson, ...
Cancers 11 (12), 1945, 2019
|Doctorate Program in Molecular Oncology and Endocrinology Doctorate School in Molecular Medicine|