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Patrick Tan
Patrick Tan
Duke-NUS Medical School
Verified email at duke-nus.edu.sg
Title
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Cited by
Year
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
R Cristescu, J Lee, M Nebozhyn, KM Kim, JC Ting, SS Wong, J Liu, ...
Nature medicine 21 (5), 449-456, 2015
20092015
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1936*2020
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
S Varambally, Q Cao, RS Mani, S Shankar, X Wang, B Ateeq, B Laxman, ...
science 322 (5908), 1695-1699, 2008
13672008
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
J Tan, X Yang, L Zhuang, X Jiang, W Chen, PL Lee, RKM Karuturi, ...
Genes & development 21 (9), 1050-1063, 2007
10482007
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma
A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ...
Cancer discovery 7 (10), 1116-1135, 2017
8062017
A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets
N Deng, LK Goh, H Wang, K Das, J Tao, IB Tan, S Zhang, M Lee, J Wu, ...
Gut 61 (5), 673-684, 2012
7302012
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
ZJ Zang, I Cutcutache, SL Poon, SL Zhang, JR McPherson, J Tao, ...
Nature genetics 44 (5), 570-574, 2012
7132012
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
KP Ng, AM Hillmer, CTH Chuah, WC Juan, TK Ko, ASM Teo, ...
Nature medicine 18 (4), 521-528, 2012
6802012
" Fluorescent timer": protein that changes color with time
A Terskikh, A Fradkov, G Ermakova, A Zaraisky, P Tan, AV Kajava, X Zhao, ...
Science 290 (5496), 1585-1588, 2000
5632000
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
N Palanisamy, B Ateeq, S Kalyana-Sundaram, D Pflueger, ...
Nature medicine 16 (7), 793-798, 2010
5592010
Exome sequencing of liver fluke–associated cholangiocarcinoma
CK Ong, C Subimerb, C Pairojkul, S Wongkham, I Cutcutache, W Yu, ...
Nature genetics 44 (6), 690-693, 2012
5232012
Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers
W Chan-On, ML Nairismägi, CK Ong, WK Lim, S Dima, C Pairojkul, ...
Nature genetics 45 (12), 1474-1478, 2013
5112013
Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target
Y Wang, ATC Lee, JZI Ma, J Wang, J Ren, Y Yang, E Tantoso, KB Li, ...
Journal of Biological Chemistry 283 (19), 13205-13215, 2008
5042008
Genetics and molecular pathogenesis of gastric adenocarcinoma
P Tan, KG Yeoh
Gastroenterology 149 (5), 1153-1162. e3, 2015
4982015
Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil
Z Lei, IB Tan, K Das, N Deng, H Zouridis, S Pattison, C Chua, Z Feng, ...
Gastroenterology 145 (3), 554-565, 2013
4892013
Oncogenic pathway combinations predict clinical prognosis in gastric cancer
CH Ooi, T Ivanova, J Wu, M Lee, IB Tan, J Tao, L Ward, JH Koo, ...
PLoS genetics 5 (10), e1000676, 2009
4392009
Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy
IB Tan, T Ivanova, KH Lim, CW Ong, N Deng, J Lee, SH Tan, J Wu, ...
Gastroenterology 141 (2), 476-485. e11, 2011
4242011
Paradoxical relationship between chromosomal instability and survival outcome in cancer
NJ Birkbak, AC Eklund, Q Li, SE McClelland, D Endesfelder, P Tan, ...
Cancer research 71 (10), 3447-3452, 2011
4132011
Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes
MK Keck, Z Zuo, A Khattri, TP Stricker, CD Brown, M Imanguli, D Rieke, ...
Clinical cancer research 21 (4), 870-881, 2015
4002015
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia
AWT Ng, SL Poon, MN Huang, JQ Lim, A Boot, W Yu, Y Suzuki, ...
Science translational medicine 9 (412), eaan6446, 2017
3622017
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