Targeting TGF-β mediated SMAD signaling for the prevention of fibrosis KL Walton, KE Johnson, CA Harrison Frontiers in pharmacology 8, 461, 2017 | 532 | 2017 |
Antagonists of activin signaling: mechanisms and potential biological applications CA Harrison, PC Gray, WW Vale, DM Robertson Trends in Endocrinology & Metabolism 16 (2), 73-78, 2005 | 290 | 2005 |
Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin CE Winbanks, KL Weeks, RE Thomson, PV Sepulveda, C Beyer, H Qian, ... Journal of Cell Biology 197 (7), 997-1008, 2012 | 248 | 2012 |
Elevated expression of activins promotes muscle wasting and cachexia JL Chen, KL Walton, CE Winbanks, KT Murphy, RE Thomson, Y Makanji, ... The FASEB Journal 28 (4), 1711-1723, 2014 | 225 | 2014 |
The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass CE Winbanks, JL Chen, H Qian, Y Liu, BC Bernardo, C Beyer, KI Watt, ... Journal of Cell Biology 203 (2), 345-357, 2013 | 225 | 2013 |
Cripto forms a complex with activin and type II activin receptors and can block activin signaling PC Gray, CA Harrison, W Vale Proceedings of the National Academy of Sciences 100 (9), 5193-5198, 2003 | 204 | 2003 |
Cumulin, an oocyte-secreted heterodimer of the transforming growth factor-β family, is a potent activator of granulosa cells and improves oocyte quality DG Mottershead, S Sugimura, SL Al-Musawi, JJ Li, D Richani, MA White, ... Journal of Biological Chemistry 290 (39), 24007-24020, 2015 | 169 | 2015 |
Oxidation regulates the inflammatory properties of the murine S100 protein S100A8 CA Harrison, MJ Raftery, J Walsh, P Alewood, SE Iismaa, S Thliveris, ... Journal of Biological Chemistry 274 (13), 8561-8569, 1999 | 168 | 1999 |
Inhibin and premature ovarian failure AL Chand, CA Harrison, AN Shelling Human reproduction update 16 (1), 39-50, 2010 | 165 | 2010 |
Prodomains regulate the synthesis, extracellular localisation and activity of TGF-β superfamily ligands CA Harrison, SL Al-Musawi, KL Walton Growth factors 29 (5), 174-186, 2011 | 155 | 2011 |
Induction of the S100 chemotactic protein, CP-10, in murine microvascular endothelial cells by proinflammatory stimuli T Yen, CA Harrison, JM Devery, S Leong, SE Iismaa, T Yoshimura, ... Blood, The Journal of the American Society of Hematology 90 (12), 4812-4821, 1997 | 140 | 1997 |
An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors CA Harrison, PC Gray, WH Fischer, C Donaldson, S Choe, W Vale Journal of Biological Chemistry 279 (27), 28036-28044, 2004 | 137 | 2004 |
Structural basis for potency differences between GDF8 and GDF11 RG Walker, M Czepnik, EJ Goebel, JC McCoy, A Vujic, M Cho, J Oh, ... BMC biology 15, 1-22, 2017 | 131 | 2017 |
Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease JL Chen, KL Walton, A Hagg, TD Colgan, K Johnson, H Qian, ... Proceedings of the National Academy of Sciences 114 (26), E5266-E5275, 2017 | 126 | 2017 |
A distinct cohort of the TGFβ superfamily members expressed in human endometrium regulate decidualization CJ Stoikos, CA Harrison, LA Salamonsen, E Dimitriadis Human reproduction 23 (6), 1447-1456, 2008 | 123 | 2008 |
New insights into the mechanisms of activin action and inhibition KL Walton, Y Makanji, CA Harrison Molecular and cellular endocrinology 359 (1-2), 2-12, 2012 | 116 | 2012 |
Two distinct regions of latency-associated peptide coordinate stability of the latent transforming growth factor-β1 complex KL Walton, Y Makanji, J Chen, MC Wilce, KL Chan, DM Robertson, ... Journal of Biological Chemistry 285 (22), 17029-17037, 2010 | 116 | 2010 |
Induction of the chemotactic S100 protein, CP-10, in monocyte/macrophages by lipopolysaccharide SP Hu, C Harrison, K Xu, CJ Cornish, CL Geczy | 113 | 1996 |
A common biosynthetic pathway governs the dimerization and secretion of inhibin and related transforming growth factor β (TGFβ) ligands KL Walton, Y Makanji, MC Wilce, KL Chan, DM Robertson, CA Harrison Journal of Biological Chemistry 284 (14), 9311-9320, 2009 | 110 | 2009 |
Activins and inhibins and their signaling W Vale, E Wiater, P Gray, C Harrison, L Bilezikjian, S Choe Annals of the New York Academy of Sciences 1038 (1), 142-147, 2004 | 110 | 2004 |