CD103+ Tumor-Resident CD8+ T Cells Are Associated with Improved Survival in Immunotherapy-Naïve Melanoma Patients and Expand Significantly During Anti–PD-1 Treatment J Edwards, JS Wilmott, J Madore, TN Gide, C Quek, A Tasker, A Ferguson, ... Clinical Cancer Research 24 (13), 3036-3045, 2018 | 349 | 2018 |
Targeting the vasculature in hepatocellular carcinoma treatment: Starving versus normalizing blood supply K Liu, X Zhang, W Xu, J Chen, J Yu, JR Gamble, GW McCaughan Clinical and translational gastroenterology 8 (6), e98, 2017 | 89 | 2017 |
Loss of sphingosine kinase 1 predisposes to the onset of diabetes via promoting pancreatic β-cell death in diet-induced obese mice Y Qi, J Chen, A Lay, A Don, M Vadas, P Xia The FASEB Journal 27 (10), 4294-4304, 2013 | 80 | 2013 |
Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation M Calao, EO Sekyere, HJ Cui, BB Cheung, WD Thomas, J Keating, ... Oncogene 32 (31), 3616-3626, 2013 | 75 | 2013 |
Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell–Mediated Immunotherapy Y Zhao, KK Ting, J Li, VC Cogger, J Chen, A Johansson-Percival, ... Cancer research 77 (16), 4434-4447, 2017 | 60 | 2017 |
Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression WD Thomas*, J Chen*, YR Gao, B Cheung, J Koach, E Sekyere, ... Oncogene 28 (13), 1605-1615 (*Co-first), 2009 | 59 | 2009 |
Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1β induction of early growth response 1 transcription B Wang, J Chen, FS Santiago, M Janes, MM Kavurma, BH Chong, ... Arteriosclerosis, thrombosis, and vascular biology 30 (3), 536-545, 2010 | 55 | 2010 |
Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ J Chen, W Wang, Y Qi, D Kaczorowski, GW McCaughan, JR Gamble, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 54 | 2016 |
骨碎补总黄酮对成骨细胞体外培养作用的机制研究 谢雁鸣, 秦林林, 邓文龙, 陈金标, 赵晋宁 中华中医药杂志 20 (3), 161-162, 2005 | 54 | 2005 |
Analysis of bone mineral density and relevant factors in 781 healthy people aged 15 to 50 L Qin, J Chen, C Ge, H Ma, W Zhang, Y Xiao, A Bao Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 33 …, 1999 | 54* | 1999 |
体重体成分与骨密度的关系 陈金标, 秦林林, 张卫, 葛崇华, 马海波, 肖艳霞 中国骨质疏松杂志 3 (2), 15-18, 1997 | 53 | 1997 |
Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2 G Aji, Y Huang, ML Ng, W Wang, T Lan, M Li, Y Li, Q Chen, R Li, S Yan, ... Proceedings of the National Academy of Sciences 117 (39), 24434-24442, 2020 | 39 | 2020 |
Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways J Li, Y Zhao, P Coleman, J Chen, KK Ting, JP Choi, X Zheng, MA Vadas, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (11), 165519, 2019 | 38 | 2019 |
Sphingosine kinase (SphK) 1 and SphK2 play equivalent roles in mediating insulin's mitogenic action L Dai, Y Qi, J Chen, D Kaczorowski, W Di, W Wang, P Xia Molecular Endocrinology 28 (2), 197-207, 2014 | 34 | 2014 |
Nuclear import of early growth response-1 involves importin-7 and the novel nuclear localization signal serine-proline-serine J Chen, MY Liu, CR Parish, BH Chong, L Khachigian The International Journal of Biochemistry & Cell Biology 43 (6), 905-912, 2011 | 33 | 2011 |
Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression Y Qi, W Wang, J Chen, L Dai, D Kaczorowski, X Gao, P Xia Journal of Biological Chemistry 290 (38), 23282-23290, 2015 | 31 | 2015 |
Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice J Li, Y Zhao, J Choi, KK Ting, P Coleman, J Chen, VC Cogger, L Wan, ... PLOS Biology 18 (6), e3000734, 2020 | 30 | 2020 |
不同月龄雌性大鼠骨质疏松模型研究 秦林林, 陈金标, 龚海洋, 马海波, 葛崇华, 张卫 中日友好医院学报 11 (1), 6-9, 1997 | 30 | 1997 |
BMP‐7 and CBFA1 in allograft bone in vivo bone formation and the influence of γ‐irradiation JB Chen, Y Yu, JL Yang, DAF Morgan, WR Walsh Journal of Biomedical Materials Research Part A 80 (2), 435-443, 2007 | 29 | 2007 |
Multiple liver insults synergize to accelerate experimental hepatocellular carcinoma JM Henderson, N Polak, J Chen, B Roediger, W Weninger, JG Kench, ... Scientific reports 8 (1), 10283, 2018 | 27 | 2018 |