| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10675 | 2021 |
| LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development Y Gong, RB Slee, N Fukai, G Rawadi, S Roman-Roman, AM Reginato, ... Cell 107 (4), 513-523, 2001 | 2666 | 2001 |
| OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28 C Alexander, M Votruba, UEA Pesch, DL Thiselton, S Mayer, A Moore, ... Nature genetics 26 (2), 211-215, 2000 | 1560 | 2000 |
| Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function VJ Davies, AJ Hollins, MJ Piechota, W Yip, JR Davies, KE White, ... Human molecular genetics 16 (11), 1307-1318, 2007 | 477 | 2007 |
| Multi-system neurological disease is common in patients with OPA1 mutations P Yu-Wai-Man, PG Griffiths, GS Gorman, CM Lourenco, AF Wright, ... Brain 133 (3), 771-786, 2010 | 437 | 2010 |
| OPA 1 Mutation and Late‐Onset Cardiomyopathy: Mitochondrial Dysfunction and mtDNA Instability L Chen, T Liu, A Tran, X Lu, AA Tomilov, V Davies, G Cortopassi, ... Journal of the American Heart Association 1 (5), e003012, 2012 | 208 | 2012 |
| International consensus statement on the clinical and therapeutic management of Leber hereditary optic neuropathy V Carelli, M Carbonelli, IF De Coo, A Kawasaki, T Klopstock, WA Lagrčze, ... Journal of Neuro-Ophthalmology 37 (4), 371-381, 2017 | 204 | 2017 |
| Clinical features in affected individuals from 21 pedigrees with dominant optic atrophy M Votruba, FW Fitzke, GE Holder, A Carter, SS Bhattacharya, AT Moore Archives of ophthalmology 116 (3), 351-358, 1998 | 189 | 1998 |
| A major marker for normal tension glaucoma: association with polymorphisms in the OPA1 gene T Aung, L Ocaka, ND Ebenezer, AG Morris, M Krawczak, DL Thiselton, ... Human genetics 110, 52-56, 2002 | 173 | 2002 |
| Treatment strategies for inherited optic neuropathies: past, present and future P Yu-Wai-Man, M Votruba, AT Moore, PF Chinnery Eye 28 (5), 521-537, 2014 | 165 | 2014 |
| A neurodegenerative perspective on mitochondrial optic neuropathies P Yu-Wai-Man, M Votruba, F Burté, C La Morgia, P Barboni, V Carelli Acta neuropathologica 132, 789-806, 2016 | 156 | 2016 |
| Clinical features, molecular genetics, and pathophysiology of dominant optic atrophy. M Votruba, AT Moore, SS Bhattacharya Journal of medical genetics 35 (10), 793-800, 1998 | 152 | 1998 |
| A comprehensive survey of mutations in the OPA1 gene in patients with autosomal dominant optic atrophy DL Thiselton, C Alexander, JW Taanman, S Brooks, T Rosenberg, ... Investigative ophthalmology & visual science 43 (6), 1715-1724, 2002 | 128 | 2002 |
| Comparative study of fibrillar collagen arrangement in the corneas of primates and other mammals S Hayes, C Boote, J Lewis, J Sheppard, M Abahussin, AJ Quantock, ... The Anatomical Record: Advances in Integrative Anatomy and Evolutionary …, 2007 | 119 | 2007 |
| Opa1 deficiency in a mouse model of dominant optic atrophy leads to retinal ganglion cell dendropathy PA Williams, JE Morgan, M Votruba Brain 133 (10), 2942-2951, 2010 | 111 | 2010 |
| OPA1 deficiency associated with increased autophagy in retinal ganglion cells in a murine model of dominant optic atrophy KE White, VJ Davies, VE Hogan, MJ Piechota, PP Nichols, DM Turnbull, ... Investigative ophthalmology & visual science 50 (6), 2567-2571, 2009 | 110 | 2009 |
| Retinal ganglion cell dendritic degeneration in a mouse model of Alzheimer's disease PA Williams, RA Thirgood, H Oliphant, A Frizzati, E Littlewood, M Votruba, ... Neurobiology of aging 34 (7), 1799-1806, 2013 | 106 | 2013 |
| Optic disc morphology of patients with OPA1 autosomal dominant optic atrophy M Votruba, D Thiselton, SS Bhattacharya British Journal of Ophthalmology 87 (1), 48-53, 2003 | 106 | 2003 |
| Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction JR Tribble, A Otmani, S Sun, SA Ellis, G Cimaglia, R Vohra, M Jöe, ... Redox biology 43, 101988, 2021 | 104 | 2021 |
| Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations C Liao, N Ashley, A Diot, K Morten, K Phadwal, A Williams, I Fearnley, ... Neurology 88 (2), 131-142, 2017 | 95 | 2017 |
